Gene Therapy And Its Effects

Gene therapy is a very controversial topic that has been discussed in the last five years and is being heavily studied to help cure cancer. Gene therapy is a technique aimed at treating genetic disorders by introducing the correct form of the defective gene into the patient’s genome (Dunlop et al., 2010).

Fifty years after the idea of gene therapy was first proposed, gene therapy has become a possible treatment for a couple different diseases. Before this treatment was approved, some serious unfavorable effects were found in clinical trials. However, these effects fueled more basic research in order to improve, in efficiency and safety. Gene therapy has been used for patients with blindness, neuromuscular disease, hemophilia, immunodeficiencies, and cancer.

The gene therapy was discovered in 1972 by authors who are advice the any author to make sure and study the gene carefully, the first try was unsuccessfully, also the first case for transfer gene in the human not count of transplantation of organ, for example it was done by Martin in 1980 , and Cline who is sad that gene was active in his patients after six months, although he did not publish this data, or it has been verified, Even if it is true, it is unlikely that it produced

Human gene therapy is when genetic material is introduced into human cells to treat a genetic disease. Instead of traditionally treating the symptoms, gene therapy aims to treat the disease’s root cause by directly altering genes and correcting defects. Therefore, gene therapy is only viable for certain diseases. Disorders from mutations in single genes are the most treatable, whereas disorders that involve many genes and environmental factors are trickier.

Since 1990, gene therapy had been tested in human clinical trials for treating such diseases as severe combined immunodeficiency disease (SCID), cystic fibrosis, Canavan's disease, and Gaucher's disease. ("Gene Therapy," n.d.). In the United States, gene therapy is only available in a research setting.

The era of scientific advancement in the twentieth century has encouraged several scientific fields to merge into a new, futuristic science called Biotechnology. One idea behind Biotechnical science is taking advantage of molecular biology. At the forefront of this advancement is gene therapy which " attempts to treat disease at its origin on the molecular level"(Kreeger,1996). "Essentially, this therapy deliberately introduces genes into the human cells to compensate for aberrant genes that cause genetic disease" (Beese, 1996). This therapy can be administered in two ways. One is germ-line therapy which not only treats the cells of that individual but these treated cells could be passed onto

Gene therapy is a technique that uses new genes to treat or prevent disease by replacing or adding new effective genes. This technique is aimed to allow doctors to treat genetic disorders without the prescribing drugs or scheduling surgery to correct the disorder. Gene therapy isn’t a fully effective method as of today. It is still undergoing tests. Several of the most common tests include introducing a new gene into the body to fight against a disease or disorder, replacing a mutated gene with a healthy gene, and removing a mutated gene in the body that is not functioning as it should be. Gene therapy is seen to be a fair treatment to diseases or disorders that have no other form of cure. It is sometimes used for inherited disorders, certain viral infections, and certain cancers. But Gene Therapy is not a certain option for treatment as of today. It is still under study as success rates are low. Genetic disorders affect one out ten people. Symptoms vary with each disease or disorder as some can appear early in a person’s life, while others appear at an older age. Genetic disorders cannot be prevented as they are passed on through a family’s genes and is within the DNA unlike a regular disease is caused by bacteria or a virus. There are two possible ways a genetic disorder can be passed on to the offspring, or child. One way is caused by dominant genes in which only one gene is altered resulting in the disorder or disease. The second way is caused by recessive genes in

Gene therapy is an amazing advance in science and medicine, but it does have its drawbacks. Since a gene cannot be directly inserted into a cell a vector is used as a carrier for this gene. Usually a virus is used as a vector because it can more easily recognize certain cells. The most common issues are unwanted immune system reactions, vectors targeting the wrong cells, infection caused by the virus, and the possibility of creating a tumor if the genes get inserted in the wrong spot in your DNA3.

Modern science is advancing perpetually each year, aiding millions of people with thousands of diseases or disorders. New discoveries happen each day. Steadily advancing the modern science front, and gene therapy is no exception. Genetic therapy can be defined as a form of transplantation of nucleic acids into a foreign subject with hopes that it will improve or even cure certain diseases or symptoms. (Dexi Lui, 1997) Medicinal practices in countries that practice western medicine seem to be directly related to technological advances. As technological understanding increases, medical practices and knowledge has the opportunity to be increased. Some of these advances are undergoing a lengthy trial period, mostly due to possible side effects, or until the proper method of administration is determined.

Gene is a relatively new but rapidly developing way to treat or cure people of certain diseases. Instead of using a drug or surgery to cure or treat someone they are using gene therapy as a way to insert a gene into the patients cells. If this technique works then it can be an amazing option for someone with a disease with otherwise no cure. Along with this new technique come many risks and dangers that question the ethics involved in doing this. Even though it is only still being tested it can be seen as a promising treatment option for many people.

Ralph Waldo Emerson once said, “to be yourself in a world that is constantly trying to make you something else is the greatest accomplishment.” While his quote offers a typical accepted cliche seen throughout modern day society, new advancements of science might be proving otherwise. Gene therapy is a new technique that allows physicians to alter one’s genetic code, effectively treating and preventing disease. Though still in an experimental stage, gene therapy has been successful in treating a variety of diseases including cancer and neurodegenerative disorders. The benefits of gene therapy are clear to the scientific community, while the limits to place on the practice are ambiguous. Specialists in the field are trying to decide how far

Gene therapy is a relatively new concept, it is an experimental technique that uses genes to theoretically treat and prevent various types of Illnesses/Genetic Disorders such as Haemophilia, Cancer, Chronic Granulomatous Disorder and Cystic Fibrosis. The process of gene therapy involves the use of a Viral Vector (Most Common Form) other forms of delivery which are non-viral include the injection of naked DNA, sonoporation and magnetofection.

Gene therapy is a field of study that focuses on the correction of mutations in DNA sequences. The ultimate goal of Gene Therapy is to prevent the inheritance of mutations that cause genetic disorders. In the medical community this is called Germ-line Gene Therapy. While this is the least ventured area of gene therapy, its has been proven to be the most promising in reference to advancing medicine to new heights when the ethical situation changes. The second  goal of Gene Therapy is to cure the patients with the genetic

For countless generations, genetic diseases have been ruining people’s lives with these abnormal conditions being able to severely mutilate, disable or kill them. Genetic illnesses are most commonly due to mutations in the DNA sequence that occurs during replication or due to environmental factors such as radiation. [10] Though an affected patient might not have to live with their illness for their whole life as the human genome has the ability to be changed [10], therefore, allowing an opportunity for treatment. Research and advancements in technology have allowed numerous different methods of treatment for affected patients to be discovered which have dramatically changed our

revolutionizing medicine and treating disease. It is believed that Gene Therapy holds the key to