Genetic Disorders: Down Syndrome

Down syndrome (also known as trisomy 21) is a disorder that makes you physically and mentally more challenged than everyone else but you are still able to grow develop and live a partially normal life. The major causes of Down syndrome are first just getting unlucky and having the 21st chromosome be irregular. But if you have a child when you are older than 35 you have a highly increased chance of getting down syndrome also if you have a sibling with Down syndrome or another kid with-it that can also increase the chance of getting down syndrome. Some symptoms of this disorder are, you can be physically less capable than others can and can have a hard time remembering things and can possibly not be able to achieve what seems to be easy things to do daily. However, most important, they only live to about 80. In addition, they can have a hard time reproducing but can still can reproduce.

Down syndrome (Trisomy of Chromosome 21) occurs when there is a defect during meiosis, typically after a mother’s egg cells have remained in suspension for a prolonged period of time (risk increases with age) or during translocation errors during early embryonic development. Individuals with Down Syndrome present physical findings of a low nasal bridge, hypotonia, lowered ears, and short stature. Patients with Down syndrome may present signs of Alzheimer’s disease around 40 years of age.

Down Syndrome is a medical condition that causes a delay in how a child develops, both mentally and physically. Each year, about 6,000 babies are born with Down Syndrome (DS), which is about 1 in 700 babies born. The cause of DS is unknown, meaning scientists don’t know how people get it, but we do know how it happens after the diagnosis. A baby is usually born with 46 chromosomes, 23 from each parent. Most likely is a DS case, the child has 47 chromosomes and has an extra “chromosome 21”. The extra genetic material is why children get DS, but scientists don’t know how it happens.

Down syndrome is a genetic condition which can cause intellectual and developmental disabilities. Persons affected with Down syndrome have the common will have an additional chromosome; instead of 46, they

Down syndrome is characterized by three different types: trisomy 21 (nondisjunction), translocation, and mosaicism. The cause of Trisomy 21 is

Down syndrome is a genetic disorder also known as trisomy 21, that develops when there is an extra chromosome inside the cells of a person. Normally a person has 46 chromosomes so when a developing infant has an extra chromosome 21 they will have 47 chromosomes in a cell causing them to develop Down syndrome. Although you might think it is hereditary Down syndrome is not passed down from parent to baby nor do we know why it happens, it occurs at conception and there is no cure for it nor does it go away.

In every cell in the body there is a nucleus and this is the location where genetic material lives. These genes are responsible for carrying the inherited traits that we get from our parents, in the form of chromosomes. Normally each cell contains a nucleus with a pair of 23 chromosomes, half of which come from mom and the other half coming from dad. The genotype in the example given is that of a person with Down syndrome. Down syndrome is a chromosomal disorder that results in learning disabilities and physical abnormalities. Most cases of Down syndrome are caused by an extra copy of chromosome 21. An extra chromosome, making 3 of one kind, is called a trisomy and the most common is trisomy 21. This may be a chromosome given to the child from the father but a portion of mothers can also pass the chromosome to the child, mothers that get pregnant over 35 years of age have been shown to pass on the chromosome. Physical appearance will lead a doctor to suspect a patient with Down syndrome but a blood test is needed to determine if the patient has the extra chromosome. Down syndrome can affect many parts of the body, there are

Down syndrome is a genetic disorder that begins to develop at the cellular level after conception. All the cells in the human body contain a center, called a nucleus, in which genetic code of each human being is stored. This genetic material, known as genes, carries the codes responsible for all our inherited characteristics from the mother and the father. Genes are grouped along rod-like structures called chromosomes. The nucleus of each cell normally contains 23 pairs of chromosomes, half of which come from each parent. In Down syndrome, however, the cells usually contain not 46, but 47 chromosomes. The extra chromosome being a number 21. This excess genetic material, in the form of additional genes along the 21st chromosome, results in Down syndrome. Ninety-five percent of all cases of Down syndrome occur because there are three copies of the 21st chromosome; it is often referred to as "trisomy 21." Chromosomes are studied by examining blood or tissue cells. Individual chromosomes are identified, stained and numbered from largest to smallest. The visual display of the chromosomes is known as a “karyotype”. (Karyotype is the analysis of counting the chromosomes in each cell)

The article “Down Syndrome” reviewed by Dr. Mary Gavin, thoroughly explains the causes, affects and diagnosis of the condition. This genetic condition involves the individual gaining an extra chromosome, ending up with 47 instead of 46. A person with Down syndrome facial and bodily features will be distinctly unique, making it easy to characterize them from others. Consistent medical attention is crucial for a child with the condition, even if the child appears to have no significant health concerns. With out proper care, the child could develop pulmonary hypertension, worsened vision and hearing, seizures, asthma, infections etc. Prenatal screening

Down Syndrome affects many people, even those who don’t have it. Down syndrome is also called Trisomy 21. The term Down syndrome did not become the accepted term until the early 1970’s (“History of NADS”). Down syndrome is the most common genetic condition, almost 400,000 Americans have Down syndrome (“What Is Down Syndrome?”). When the 21st chromosome has an extra copy, full or partial, down syndrome will occur. With the extra genetic material it messes with the development physically and mentally. It also creates certain features connected with Down Syndrome. Some of the well known features are low muscle tone, small stature, upward slant to the eyes, and a single deep crease across the center of the palm (“What Is Down Syndrome?”). These features and their extent can vary from person to person, some may not even have any at all. One in every 691 babies born in the United States has Down syndrome, about 6,000 babies are born with Down syndrome each year in the United States (“What Is Down Syndrome?”). Just like the physical features the medical problems associated with Down syndrome vary from person to person, some may need a lot while others may need little to none. The health problem can be treated with the many resources available to help the people with Down syndrome and their families.

What is down syndrome? Down syndrome is a diseases that is a natural born diseases. Down syndrome is a chronilogical disease. It affects 1 in 800 lives born out of 1 in 1000. What are down syndrome symptoms? Symptoms of down syndrome are mental retardation sometimes have difficulties learning and usually a very characteristic facial. Down syndrome is one of the hardest deasese to diagnos. They do a genetic blood and skin test to afferm the down syndrome deases. Trismoy 21 means that every cell in the body has 3 copies of chromosomes inside the trismoy. When there is ussually only two copies of chromosomes down syndrome people have 21 copies. Having any extra amount of chromosomes it will cause growth defections. With 21 chromosomes in the

Down syndrome, also known as trisomy 21, is a genetic disorder caused by a third duplicate of chromosome 21. Down syndrome was first recognized as a distinct condition in 1866 by John Langdon Down, after whom the disease is named. Until 1970, the disorder was known as Mongolism and only recently become accepted as “down” syndrome. In 1959, French geneticist Professor Jerome Jejune discovered an extra chromosome to be the cause for the physical and intellectual abnormalities seen in individuals with DS. (Kazemi, Shojaei, & Sadighi, 2016). Down syndrome affects approximately one in every 1200 babies that are born, making it the most common genetic disorder. (Jobling, Virji- Babuls, & Nichols, 2006).

Down syndrome is an increasingly prevalent disease in the US. It is a genetic disease that is caused by an extra 21st chromosome. One in about every 800 live births has Down syndrome. Down syndrome is the most common form of both identifiable retardation and genetic diseases. Genetics is the study of how certain traits are passed from parents to their children. Genes are the basic unit of heredity. Cells are the building blocks of a person’s body. We each have more than a trillion cells. Our genes are located in chromosomes. Each cell has 46 chromosomes or 23 pairs. In the 1900’s, French researcher, Mr. Lejeune, identified Down syndrome as a chromosomal condition. He observed 47 chromosomes in the cells of individuals with Down syndrome,

In addition, Down syndrome disorder influences individuals of any age, races, religious foundations and financial circumstances. It is a genetic disorder that is produced by an added duplicate of chromosome 21. Down syndrome has physical characteristics. For instance, Down syndrome people have poor muscle tone, short arms and legs, flat noses and even have round faces. However, the Down syndrome physical characteristics conditions can cause intellectual disability. Down's Syndrome (2016) concluded: “The diagnosis of Down's syndrome is usually made soon after the birth of the baby because of the baby's appearance.” Basically, there are numerous physical attributes related to the condition, which may lead a parent or birthing specialist, or other therapeutic experts, to presume that the child has Down syndrome disorder.

Down syndrome is where every cell in the body has a nucleus, genetic material is then stored in genes. Some of those genes carry codes that are responsible for the inherited traits that are grouped up along rod-like structures that are called chromosomes. Down syndrome is the part that occurs when one individual has a partial or full copy of chromosome 21. The nucleus of each cells contain 23 different pairs of chromosomes, half of those which are inherited from each of the parent. Some common traits of Down syndrome are low muscle tones, upward slant in the eyes, and single deep crease across the center of the palm. Approximately 400,000 Americans have Down syndrome and almost 6,000 babies with Down syndrome are born in the United States