Genetic Evidence Reveals Clues to Roots of Bipolar Disorder

“Bipolar disorder, also commonly known as manic depression, is defined as a serious mental illness in which common emotions become intensely and often unpredictably magnified. Individuals with bipolar disorder can quickly alternate from extremes of happiness, energy and clarity to sadness, fatigue and confusion. All people with bipolar disorder have manic episodes abnormally elevated or irritable moods that last at least a week and impair functioning. But not all become depressed ” (American Psychological Association, 2015). Bipolar disorder can vary in each individual. The symptoms fluctuate in pattern, severity and rate of recurrence. Some people are more susceptible to either mania or depression, while others change proportionately between the two types of episodes. Some have frequent mood disruptions, while others live through a few throughout their lifetime.

Scientist has also founded that bipolar disorder is also hereditary by adoption studies. This study will show if the biological parent or sibling from the adoptee is ill even if he or she has not grown up in the same environment. Adoption studies has shown that the blood relatives has the same mood swing rate as the adoptee, therefore, leads that genetics plays an important role to bipolar disorder. Another theory is, mood swings may be caused from too much stress or major life changes along with, one’s sleep

Bipolar Disorder is a brain disorder that is characterized by abnormal changes in mood, energy and activity levels (“National Institute of Mental Health”). Manic-depressive illness is also another name that bipolar disorder is commonly referred to as (“National Institute of Mental Health”). This disorder has four basic types including, bipolar I, bipolar II, cyclothymic, and any other which do not perfectly fit the first three. All four of the types have episodes of extreme highs, manic periods, and extreme lows, depressive periods. Symptoms can range greatly and depend on what type of episode the affected is having. Manic episodes can include, but are not limited to: having extraordinarily high amounts of energy, activity,

Approximately 0.5-1 percent of Americans will develop bipolar II disorder in their lifetime, worldwide the prevalence is 0.4 percent (Rosenberg & Kosslyn, 2011). Bipolar disorder is one of the main causes of disability, because of its cognitive and functional impairment, the high rate of medical and psychiatric comorbidity, and the relevant suicide risk (Dell 'Osso, et al., 2016). Bipolar II disorder is one of the two most commonly diagnosed subtypes of Bipolar disorder, which are distinguished by the amount of burden the depression causes, the number, frequency, duration, and severity of the depressive episodes, and the occurrence of specific sub threshold episodes (Dell 'Osso, et al., 2016). Although bipolar II disorder diagnosis are on the rise we lack extensive research on the features and treatments of this disorder (Datto, Pottorf, Feeley, Laporte, & Liss, 2016). Bipolar II disorder is now recognized in the latest Diagnostic and Statistical Manual of Mental Disorders (DSM-5) under a new chapter dedicated specifically to bipolar disorders. Which proves that bipolar disorders are their own set of disorders in terms of symptomatology, family history, and genetics (Möller, et al., 2014). This allows an enhancement in the accuracy of diagnosis, which in turn leads to earlier treatment. In the DSM-5 it states that bipolar II disorder can lead to effects such as disability, comorbidity, mortality, and an impact on the quality of life (Datto, Pottorf,

Bipolar disorder also known as manic depression has always been a mystery since the 16th century. History has shown that it can appear in almost everyone. Bipolar disorder causes mood swings in energy, thinking, and other behavior. Having a bipolar disorder can be very disabling (Kapczinski). A study was evaluated and about 1.3% of the U.S population of people suffers from bipolar disorder. Stressors and environmental influences can trigger and cause a person to go through numerous episodes. Bipolar disorder is characterized according to the severity of the stages. According to Kapczinski, there are four different stages that a person with bipolar disorder can experience. The prognosis of a disorder is different in each particular patient

Bipolar disorder is a mental abnormality involving an intense mood change from mania to a depressive mood in a matter of seconds. This used to be called manic-depressive disorder. During the manic phase, your will be very energetic, happy, talkative, have an increased sex drive, and even aggression. You could also end up spending a mass amount of money in which you didn’t intend to do. But during the depressive phase, you are very depressed, hopeless, anxious, sleepy, guilty, and sometimes even suicidal. People with bipolar disorder, often struggle with psychosis as well. Psychosis is the hallucinations and hearing voices.

This source gives the readers an in-depth overview of Bipolar Disorder and the causes of having the mental health issue. There’s a great distinction between the ups and downs people experience and bipolar disorder. Due to the ups and downs teens and children experience, bipolar disorder is hard to diagnose during those early years. The National Center of Biotechnology Information’s research program is run by Senior Investigators, Tenure Track Investigators, Staff Scientists, and Postdoctoral Fellows which makes the source credible. The source contained

Jann States that sufferers of BPD are three times more likely to suffer a depressive episode than a manic or hypomanic episode. (Jann, 2014) The Joanna Briggs institute Identified that the suicide rate for bipolar suffers are 15 times higher than that of non-affected individuals of the same age and sex. Eighty percent of these suicides occur during a depressive episode. (Hung Chu, 2016). Therefore appropriate pharmacological therapy not only during the maintenance period to reduce reoccurrence but also during these acute episodes is highly important. Pharmaceutical treatment includes the use of medication such as mood stabilizers, anti-psychotics and anti-depressants. The Joanna Briggs institute recommends that combination therapy involving both mood stabilizers such as Sodium valproate or lithium valproate and antipsychotics risperidone, olanzapine, quetiapine and haloperidol is best to treat acute mania associated with Bipolar. As it increases adherence to medication regime. (Tufanaru, 2016) The same institute encourages the use Olanzapine as a monotherapy or in combination with fluoxetine in the treatment of Depression associated with Bipolar disorder. (Hung chu, 2016) Lithium continues to be the first line mood stabilizer under current guidelines but may be used in conjunction with Carbamazepine where depression is evident. (Hung chu, 2016) The Australian and New Zealand Journal of Psychiatry 2015 also shows preference for combination therapy

Bipolar disorder, according to the National Institute of Mental Health (NIMH), is “a brain disorder that causes unusual shifts in mood, energy, and activity levels,” and

Bipolar disorder is a mental disease that causes a rapid shift in mood, usually between mania and depression. The manic episode of bipolar disorder usually results in an abnormally large dosage of energy. During manic depression, an individual may go on an unnecessary shopping spree or even quit their job. Mania is usually followed by an episode of depression, which could lead to suicide if not properly treated. Bipolar disorder is usually treated through medication. Medication for bipolar disorder usually includes a mood stabilizer, such as Lithium, with an anti-psychotic drug, such as Zyprexa (Bipolar Disorder, n.d.). While medicine is the more popular remedy for leveling the mood of a bipolar disorder patient, meditation has also been

Bipolar disorder, or manic depressive disorder, is a disorder characterized by extreme mood changes. People with this disorder undergo unusual shifts in his or her mood, activity levels, energy and the ability to carry out daily activities (National Institute of Mental Health, n.d.). A person can go from being very outgoing and energetic to feeling irritated and worthless over a period of a few days, months, or even years. People with bipolar disorder experience “mood episodes”, represented by a drastic change in a person’s unusual mood or behavior (National Institute of Mental Health, n.d.). A manic episode he or she may experience is overexcited and overly joyful; however, someone in a