Genzyme 's Focus On Orphan Drugs

Tidd and Bessant (2009) argued that “Unless an organization is able to move into further innovation, it risks being left behind as others take the lead in changing their offerings, their operational processes or the underlying models that drive their business”.

Desperately Seeking Synergy and Competing on Capabilities Reaction paper I.) I didn’t think that synergy was that much big of a deal until I read this article. I am one of those who assume that synergy exists, can be achieved, and will be beneficial, I didn’t really think about the downsides of

Spending $3 billion a year on research, Merck enjoyed a decade long span of unveiling new drugs on a regular basis (Lawrence & Weber, 2014). This was a major contributing factor to Merck’s ranking as the third largest pharmaceutical company in the world (Lawrence & Weber, 2014). In the 1980’s, 80% of the drug companies’ growth was attributed to drugs that addressed chronic, nonfatal conditions that affected a large population (Lawrence & Weber, 2014). These drugs, often referred to as blockbuster drugs, were usually taken by patients with health insurance which insured healthy sales and profits for the drug companies (Lawrence & Weber, 2014). Merck was in stiff competition with other drug manufacturers to create the next big blockbuster drug that would drive up profits. Coupled with that pressure was the amount of time involved in

The industry is making lower quality material even though they have the money to spend, corruption is somewhat common among the industries. ”We're not adding any patient to the population of those that could benefit from the drug. As far as the patients are concerned, it is a complete waste”(Drugs For Rare Diseases Have Become Uncommonly Rich Monopolies)Drug pricing can be manipulated through law and availability, naturally a drug for a rarer disease will be more expensive, the companies use this to clinch more financing. The general majority is not being taken care of as much as the minority population with rare diseases. Drugs developed for rarer diseases are called “Orphan Drugs”. The research being payed for by taxpayers and the federal government is being used for developing more orphan drugs than drugs for more common diseases. This wastes some time and money, as orphan drugs typically take a lot longer to develop than other drugs. Although orphan drugs

Ways to Be a Strategic Leader Many of the difficulties confronted by organizations stem from the refusal of its leaders to address issues in a timely basis. If instead of procrastinating, these leaders developed strategies for the future of the organization, many obstacles and challenges could be avoided, yet in my over thirty years of working closely with organizations and their leaders, I have found very few leaders who are strategic thinkers. Strategic leadership involves numerous activities, but begins with a leader who realizes the need to be proactive instead of reactive.

And of the time spent looking forward, no more than 20%is spent attempting to build a collective view of the future (the other 80% is spent looking at the future of the manager’s particular business). Thus, on average, senior management is devoting less than 3% (40% x 30% x 20% = 2.4%) of its energy to building a corporate perspective on the future. In some companies the figure is less than 1%. Questions go unanswered because to address them senior managers must first admit, to themselves and to their employees, that they are less than fully in control of their company’s future. So the urgent drives out the important, the future goes largely unexplored; and the capacity to act, rather than the capacity to think and imagine, becomes the sole measure of leadership.

Response to Change As Thompson (2015) has discussed, the world is changing fast and organizations must be flexible in handling changes to be able to thrive well or they may experience dilemmas. In 1997, Apple Company, which almost reached bankruptcy ousted its that time CEO, Gil Amelio, where Steve Jobs replaced him and declared himself interim CEO. Apple that time is experiencing a disruptive change, a change that is radical and immediately happening, in other words unexpected. However, they were able to response to it quickly and prevented the company to hit the very bottom by bringing back Steve Jobs. Jobs had so much idea with him, which the company needed most at that time (Time, 2016).

An innovative organization engages everyone throughout the organization in the task of developing and implementing new ways to reach the organization's goals. (Behn, 1995) For organizations to build leadership strength, they first need to know what elements of leadership are needed and valued in the organization and for what roles. (Leslie, J. 2009) The two skills I feel are necessary for the success of innovation and the formation of a successful innovative organization is Strategic Planning and Leading People. Within the initial creation of an innovation and innovator must have a strategic plan set to meet small goals in order to obtain or create that unique innovation. A strategic plan is a document used to communicate with the

This can be clearly illustrated by the situation Gillette faced during the leadership of the CEO Vincent Ziegler. He started to buy other companies and failed to generate more profit. At first his plan looked very promissory and generated revenue but at the end the company ended up losing money and time they could have invested in their own business.

High potential people take on demanding multiple projects and leadership roles. Unforeseen events occur that delay or derail critical business initiatives under their responsibility. more...

Running head: EFFECTS OF POOR LEADERSHIP 1 EFFECTS OF POOR LEADERSHIP 4 A Qualitative Study on the Effects of Poor Leadership Decision Making Prepared for: Dr. E. J. Bondoc Shorter University Submitted by: Yushica Willis July 06, 2016 Table of Contents Abstract 4 List of Tables 5 List of Figures 6 Section 1: Introduction 7 Background/Situation 8 Problem/Issue 9 Evidence to Justify the Study 10 Definition of Terms 12 Summary 14 Section 2 Literature Review (Relevant Published Information) 16 Theme 1 16 Theme 2 17 Theme 3 18 Theme 4 Error! Bookmark not defined. Summary 19 Section 3 Analysis 20 Relevant Facts About ABC Company Error! Bookmark not defined. Detailed Information about the Specific Issue or Problem 20 Analysis of the Causes of the Situation/Problem Issue 20 Alternatives and Possible Solutions 21 Solution 1: Title 21 Solution 2: Title 22 Solution 3: Title 23 Section 4: Recommendations and Conclusions 24 Appendices 26 Appendix A ? Request for Applied Research Project Approval 26 Appendix B ? Action Plan and Schedule 27 Appendix B ? Action Plan and Schedule 29 Appendix D ? Employee Empowerment Survey 30 References 31 Abstract Myriads of global scale organizations are successful due to the ability of leaders to make proper strategic decisions and also implement them. Therefore, the ability of executives to make relevant and strategic decisions not only places the company at a competitive

Leaders of innovation must imprint their DNA onto their organization to the extent that it resonates throughout the workforce. If a leader is able to successfully accomplish this task, the workforce will become an integral part of the innovative process within their organization. Former CEOs, Vineet Nayer of HCL Technologies, Steve Jobs of Apple and Jeff Bezos of Amazon are examples of leaders who were able to successfully utilize the five discovery skills described by Dyer, Gregersen, & Christensen (2011) to develop an innovative culture throughout their respective workforces in order to boost the overall innovation of their companies. Specifically, Nayer, was able to quickly surmise that his IT company was at risk of losing market shares, struggling to keep up with their competitors and were not prepared to face the changes that here taking place in the IT services industry at the time. The following paper will explore the global trends that influenced the need for Nayar to create a more innovative organization and the relationship between the global trends and Nayar 's role as a leader of innovation. In addition, the article will analyze Nayar’s use of the five discovery skills as an innovation leader and finally explore recommendations for better use of the discovery skills.

We also document the sources of financial commitment that enabled these strategic managers to sustain the uncertain innovation process until it could generate financial returns. In focusing on the roles of strategic control and financial commitment in sustaining the innovation process, this study suggests an alternative to conventional agency theory for explaining the relation between the governance of resource allocation and economic performance at Rolls-Royce. According to agency theory, the entrenchment of Rolls-Royce’s managers should have resulted in a squandering of the company’s resources, not superior economic performance. The fact that these managers exercised strategic control, and developed the RB211, under very different ownership structures also raises questions about the importance of ownership to corporate performance and the conditions under which a high-tech company that must make uncertain and expensive investments in technological development can be exposed to the demands of public shareholders. This study, therefore, sheds light on the role of not only career managers but also public shareholders in the innovation process. The next section describes how Rolls-Royce’s attempt to develop the three-shaft engine for Lockheed at the end of the 1960s resulted in bankruptcy. Then we detail how, as a nationalised company from February 1971 to May 1987, Rolls-Royce

Then, according to Zahra (1996) article named "Technology strategy and new venture performance: a study of corporate-sponsored and independent biotechnology ventures", the development of technology has given rise to many opportunities for enterprises in many ways. This article presents 10 hypotheses, and the author collects data from 112 new US

Harvard Business review have identified few processes that enables organizations to devise a strategy and initiates to be successful in adapting to the rapid change happening in today`s world. Below graphic depicts those processes and next section describes each of those. Fig 3 (Kotter, 2012) A sense of urgency to be