Germline Engineering and Reprogenetic Technologies Essay

A Preimplantation Genetic Diagnosis (PGD) is a test that “allows future parents to detect genetic defects that cause inherited disease in human embryos before they are implanted.” One of the most ethical questions that one might ask before considering the PGD is whether the benefits of genetic knowledge outweigh harmful effects that occur to the embryo? Is it really worth manipulating embryos genes in order to achieve the desire of the parents? Often times we have to take into considerations the risk and benefits of each situation. I believe that the PGD test should be only be done to detect genetic defects, but it should not be used to manipulate genes in order to make what to them is a “perfect” child. As stated in our text, “ In the united Kingdom alteration of an embryos genes, even for gene therapy or cloning embryos is illegal.” By manipulating genes its like going against Gods wishes. In the eyes of God every person that comes into this world is equally seen as a human being because they are all created in “ the image of God.” In this case the parents should not be allowed to manipulate the genes of their unborn child just to accommodate to their

Also, with germ line modification, couples would be able to enhance certain characteristics of their future children. Koshland says that germline alteration could meet future ‘needs' to design individuals "better at computers, better as musicians, better physically" (CRG). James Watson has told researchers to "try to prevent ugly babies and stupid people and to reduce the odds that anyone will be shy or a ‘cold fish'" (McKibben 22). The basic selling point of germ line modification that supporters like Watson seem to be focusing on for the long term is the possibility of the ‘enhancement' of desired traits. In other words, the possibility of designer children (CRG).

Gina Kolata’s article, Ethics Questions Arise as Genetic Testing of Embryos Increases (2014), explains that as the increase of the testing of embryos for parents to choose whether or not to have children has also brought its ethical questions in the light. Kolata uses the Kalinskys case, a family in the article, and how their neurological disease, Gerstmann-Straussler-Schinker (GSS), has raised questions for ethicists who have looked into the case. Kolata’s purpose in writing this article is to inform the audience on the growing topic of embryo testing and also the ethical question that also accompany in order to have the audience to develop a personal view on the issue. Given how the author explains the technical terms used within the article, Kolata is writing to an audience that is not fully aware of genetic testing.

Although this may be the case in many areas of people’s lives today, it is not always beneficial, or necessary. People may have trouble deciding whether messing with human genes and cells is ethical. Designing the “perfect child” in many parent’s eyes becomes a harsh question of reality. The concept of a parent’s unconditional love for their child is questioned because of the desire to make their child perfect. If genetically engineering humans becomes a dominant medical option, people could have the chance to create their child however they like: from physical appearances, genetically enhanced genes, and the possibility to decide what a child thinks and acts, parents have access to designing their entire child. Naturally, people could be creating a super-human. Issues between different races, and eventually creating new prejudices against genetically engineered humans may increase. People may not realize how expensive genetic screening is at first. With only the rich being able to “enhance” their children, another social issue might occur, giving the world another type of people to outcast.

Though it is evident that the concept of “Designer Babies” would prove unpopular amongst the majority of society, there still remains to be advocates for a future compromising of GM children. It is argued that gene technology will bring about a new age of human beings who are happier, smarter and healthier. Supporters look forward to a future when parents could quite literally assemble their children from genes listed in a catalogue. A future in which the health, appearance, personality and life span of our children become mere artefacts of genetic modification.

The escalating supremacy and receptiveness of genetic technology to engineer and "design babies," now gives parents the option to modify their unborn children, consecutively to prevent their offspring's from receiving genetic disorders such as: "sickle cell diseases, cystic fibrosis and down syndrome ," or conceivably, make them blue eye coloured, intelligent or else blessed with enviable qualities. Would this mean there will be an increase in the superiority among the rich, both physically and mentally, or will this modification be available for all to exploit, or would we be evidencing engineered babies facing unexpected genetic predicament? The highly contentious issue of designing unborn children to be a perfect "epitome" is thoroughly investigated and examined in the article of, lead author of

Imagine a world where maladaptive genetic diseases have ceased to exist, parents have the ability to alter and improve their unborn child’s attributes such as height, intelligence, and attractiveness, and each generation becomes healthier, smarter, and stronger. Sounds like an unfeasible utopia, does it not? However, due to scientific advancements in the field of embryonic gene modification, this fantasy may soon become a reality. In a nutshell, embryonic gene modification refers to scientists altering the genome of an embryo in vitro for a multitude of reasons, ranging from eliminating harmful genetic diseases to altering superficial characteristics. Although embryonic gene modification may seem like a dream come true to many, it is not without ethical concerns that require intense debate.

Science and technology are always pushing forward and leading us to new discoveries, dramatically altering life as we know it. One of the newest discoveries is the genetic enhancement of infants, also known as designer babies or germline enhancement. Scientists take the human embryo and enhance its genetic makeup to ensure a particular gene is present or to remove the gene altogether. The manipulation of the unborn child’s genes will pose unknown risks and will be done without their consent. The controversy of this deception will further destabilize society and its unity. The genetic enhancement of infants should be opposed because it is unethical and dangerous to civilians and society.

As well as having the ability to alter plant life, this technology is also said to be able to alter or manipulate human genes. Scientists are finding ways to manipulate certain genes to reduce the risk of Parkinson’s disease, Huntington’s disease, as well as depression. In the essay, Richard Hayes writes, “Last year Science magazine reported that a variant of the human 5-HTT gene reduces the risk of depression following stressful experiences” (185). By inserting the variant of that gene into embryos, some babies could have a chance at never experiencing depression. This would be an amazing feat, to be able to give a child a chance to never have to feel the devastating effects depression can have on a person. There are other disorders other than depression that could also be cured from the manipulation of human genes. Many children today are born with autism and Down syndrome. This technology could one day ensure that all babies are born completely healthy with no defects or disorders

Parents wish for their children to be perfect and, more so, healthy. Through the advancement of modern technology and science, giving birth to a child of desired hair color, body type, and without any physical or mental ailments could be a reality for all parents, whether or not they are carriers of certain genes. Genetic modification, sometimes called “germline editing,” has the potential to allow for medical doctors and scientists to not only change certain characteristics of a human embryo, but to also alter the future of humanity itself. While this process has many proponents, the modification of the very essence of human life has some people worried. This is, in fact, uncharted territory in the scientific world, and the extent of the possible

New technological advances and scientific methods continue to change the course of nature. One of the current controversial advances in science and technology is the use of genetically modified embryos in which the study exceeds stem cell research. Scientists have begun planning for research involving human embryos in the genetic modification field. Many technological developments are responsible for improving our living standards and even saving lives, but often such accomplishments have troubling cultural and moral ramifications (Reagan, 2015). We are already beyond the days in which virtually the only procreative option was for a man and a woman to conceive the old-fashioned way (Reagan, 2015). Genetic modification of human embryos can be perceived as a positive evolution in the medical process yet it is surrounded by controversy due to ethical processes. Because this form of genetic modification could affect later born children and their offspring, the protection of human subjects should be a priority in decisions about whether to proceed with such research (Dresser, 2004). The term Human Genetic Engineering was originally made public in 1970. During this time there were several methods biologists began to devise in order to better identify or isolate clone genes for manipulation in several species or mutating them in humans.

With new technologies available everyday, it seems almost as if we can customize our children. Reproduction is no longer an outcome of random and inherited genes, but now it’s a process of creating the child that we want to have. Fertility clinics are in debate as to whether or not it is ethical to be able to determine the sex of our children. Some view this as a valid option, while others see it as another step down the road to designer babies. But how far is too far? That is a question that we can only answer for ourselves. While this article remains unbiased, we are able to form our own opinion after seeing the pros and cons of both sides.

By examining the genetic makeup of the fetus, inducing changes in his or her embryonic stem cells could modify the genes. Studies show that most parents want only the best for their child and by enhancing his or her genes allows the child to be the best. From the perspective of a child genetically modified, this threatens his or her freedom of action. Whether the child succeeds in life is not wholly determined by his or her efforts to do well, but determined by decisions made by parents before birth. No longer able to accept responsibility for the things the child does, it is speculated that parents will no longer view their children as something they are obligated to raise and love. Instead, the parents would see their child almost like a mere consumer product that they have high expectations for before they buy it. The freedom of action a child has would be destroyed through a parent’s high expectations.

Genetically engineering the human genome, also known as the complete set of genetic material, is now more than just science fiction, after 25 years of collecting and analyzing scientific research, altering the human genome is becoming a concrete reality (Yu-Wai-Man 1323). Genetically modifying the human genome is deliberately altering human genes for the purpose of producing offspring with those genetic changes. Understanding the history of genome engineering, knowing the procedures, and being aware of the ethical issues of this aggressive approach to curing human genetic diseases are the main aspects to grasping the whole knowledge of germline engineering on human embryos and gametes.

What if you could design your child before it was even born? What if you could cut out any life threatening diseases, make sure that your child is not susceptible to smoking addictions or alcoholism, and then make your child genius? Would you? Are you asking yourself how this could be done? Have you ever considered human genetic engineering?