Glioblastoma Multiforme Case Studies

Once a person has been diagnosed with brain cancer, treatment should begin immediately. Treatment for brain tumors involves any combination of surgery, radiation, and chemotherapy. Some tumors require several different surgical procedures; some can be treated with radiation alone. Surgery is the best process to remove a brain tumor. Surgery attempts to remove most, if not all of the tumor. Once most of the tumor is removed, the rest of the tumor can be removed through a process called radiotherapy.

Glioblastoma is the most common and aggressive form of malignant brain cancer in adults. On average, 8 of every 100,000 people in the U.S. are diagnosed with glioblastoma every year – representing approximately 2% of all cancers diagnosed [1]. Glioblastoma tumors form when astrocytes, star-shaped cells which support and protect the brain, re-enter the cell cycle and start to rapidly divide. Because the brain is supported by a large network of blood vessels, tumors grow quickly and are difficult to remove surgically. Present treatments for glioblastoma are limited to surgery, radiation therapy, and chemotherapy; however, despite these interventions tumors are likely to regrow. Consequently, typical survival time following glioblastoma diagnosis is less than 2 years.

Glioblastoma (pronounced like gleO blastoma) is an incurable brain cancer,Survival rate is usually measured in months.This became a word that was instantly defined, researched, dissected, feared, and tried to comprehend and understand by family,friends and acquaintances of Larry McKee (McKee)who was personally affected from this single word, it was quickly added to their vocabulary, because of the of the events that transpired on October 22, 2011 that forever changed lives “Glioblastomas are tumors that arise from the astrocytes- the star-shaped cells that make up the “glue-like,” or supportive tissue of the brain. These tumors are usually highly malignant (cancerous) because the cells reproduce quickly and they are supported by a large network of blood vessels.”(A.B.T A..) He was diagnosed with stage four.

Brain cancer develops from cells within the brain. The brain controls the vital functions of the body, including, speech, movement, thoughts, feelings, memory, sight, hearing, and more. Brain cancer affects people in many different ways. Brain cancer is diagnosed at the local stage in 76.6% of people. The 5-year survival for localized brain and other nervous system cancer is 36.3%. Brain cancer will cause anything from headaches to balance and walking problems, changes in your vision, muscle twitches, memory problems, and nausea and vomiting.

Cancer has one of the biggest effects on the patients mental health but also the patients loved ones and friends. It is one of the hardest things to get a grip on when the doctor tells someone that they have cancer and a fifty-fifty chance of making it. "The disease can bring many changes-in what people do and how they look, in how they feel and what they value" (Dakota 4). It makes people look at the world and their lives in a different way, valuing now what they took for granted and seeing the bigger picture in every scenario. It is something that no one can actually brace, even after the doctor tells them. Through it all though, the person must remain strong and optimistic because the cancer can affect the person's moods and in return affect the outcome of the person and the chances of their making it

Tumors can be classified into three types: 1) benign 2) pre malignant 3) malignant tumor. Benign tumors are those which are incapable of abrupt expanding and affecting the other healthy brain tissues. Premalignant tumor is a pre cancerous stage, if not treated properly it may lead to cancers. It is often considered as a disease. Malignant tumor grows rapidly with time an ultimately leads to death of patient. Malignant is a medical term describing a sever growth of a disease. The most common primary brain Tumors are gliomas, wherein 70% are in the group of malignant gliomas, glioblastoma multiform (GBM).The GBM is one of the highest malignant human

Glioma is a tumor that is a type of brain cancer. Glioma tumors are made up by cells called glial cells. Glial cells normally provide nutrition, oxygen, and structural support to the brain. Three types of glial cells can produce tumors. Gliomas are named after the type of glial cell that is involved in the tumor. A tumor is formed when the glial cells grow into an abnormal mass of tissue. Gliomas are one of the most common types of brain tumors that occur in adults.

You had actually been hopeful at first, maybe you’d be one of the few lucky survivors of this merciless disease, until the doctor came and told you that you had less than two months left... And that was seven weeks ago.

“’So what’s your story?’” she then then replies “’I already told you my story. I was diagnosed when-‘” He interrupts and says “’No, not your cancer story. Your story. Interests, hobbies, passions, etcetera… Don’t tell me you’re one of those people who becomes their disease. I know so many people like that. It’s disheartening. Like cancer is in the growth business, right? The taking-people-over business. But surely you haven’t let it succeed prematurely’” (Green, 32).

What is Cancer? Cancer is many diseases which involve abnormal cell growth. Cancer cells are able to replicate and spread because they completely lose control and are not able to be restrained. These cells will then form to become tumors. There are two types of tumors called malignant and benign. The malignant tumor is the cancerous tumor. The benign tumors are much less destructive to the body. To tell the difference is quite simple, a malignant tumor has the ability to spread through metastasis causing the cancer to attack multiple areas, whereas the benign tumors cannot spread and are in most cases nonthreatening. Although there are numerous types of cancer, such as breast cancer, lung cancer, and kidney cancer, I chose to write about brain

The diseases associated with FUBP1 include oligodendrogliomas, astrocytomas, and oligoastrocytomas. Oligodendrogliomas are primary glial brain tumors and can be either low-grade (grade II) or high-grade (grade III). [2] Since oligodendrogliomas have a slow growth rate, they are often present for years before they are diagnosed. Nevertheless, the most common symptoms include: seizures, headaches, and personality changes. Altogether, the symptoms vary by location and size of the tumor. About 66 to 78 % of people with grade II oligodendroglioma survive for about 5 years after diagnoses, while 30 to 38 % of people with grade III will survive for about 5 years after they are diagnosed. [3] Astrocytoma is another type of brain cancer that stats in the cerebrum, which is the largest part of the brain, but can also appear in the cerebellum, which is the back of the brain. It is more common in men than in women. Like oligodendrogliomas, the most common symptoms of astrocytomas include: headaches, seizure, changes in behavior and memory loss. [4] Prognosis of astrocytomas depends on the type of astrocytoma. Altogether, a low-grade astrocytoma (LGA) has an 83 % 10-year overall survival, while the overall survival rate of a high-grade astrocytoma (HGA) range between 15-20%. In both oligodendrogliomas and astrocytomas, the FUBP1 locus is mutated which leads to the inactivation of

There are different types of cancers. There is Leukemia, Breast cancer, Throat Cancer, and more. Then, theres the cancers that not a lot of people think about. Cancers that exist, but are unknown to most people. They are very rare and not a lot of people have it, but it’s still there affecting people in the same ways, even worse, that any known cancer affects people. One of the is Central Nervous System AT/RT Cancer.

When cancer develops elsewhere in the body and spreads (metastasizes) to the brain, it’s called a secondary brain tumor, or metastatic brain cancer. Metastatic brain tumors are more common than primary brain tumors. Some cancers that commonly spread to the brain

Glioblastoma Multiforme is an extremely aggressive brain tumor that can drastically alter how the body moves, a person’s memory, vision, emotion, thought, etc (GBM Guide). Having something in your brain that has the potential to drastically

Another major breakthrough that occurred in the early 1970’s was the discovery of the first promising chemotherapy for glioma. A glioma is a malignant tumor that begins in the glial cells which surround the nervous system. Gliomas can be found in the brain and spinal cord. Researchers studied a chemotherapy drug called carmustine (BCNU) and