Guerrini's Polio And Primates

Polio an American story is a scholarly readable and informative book which covers the lives of many American eminent scientists who struggled a lot to eradicate polio. This book mainly focuses on the mid twentieth century where the people are very eager to find a vaccine to eradicate polio .This book also covers the entire topics from appearance of polio symptoms to post polio syndrome which shows the valuable thesis done by David M. Oshinsky.

The main way a patient can learn about all of their rights and the ins and outs of their procedure is by signing a consent form. The AHA describes the purpose of a consent form by writing, “this process protects your right to consent or refuse a treatment. Your doctor will explain the medical consequences of refusing recommended treatment. It also protects your right to decide if you want to participate in a research study” (AHA 4). The AHA brochure describing fair treatment and patient’s rights was made in 2003, about fifty years after Henrietta’s case. But most of this seems like common ethics, and people should have upheld these same values then, but because common ethics were not laws in the fifties, what

Heather Green Wooten’s The Polio Years in Texas: Battling a Terrifying Unknown chronicles the history of polio in Texas in a very extensive timeline. The book goes all the way back to the beginning of the polio epidemic and essentially progresses to the present. The time in this book certainly exceeds that of, The Captured and Isaac’s Storm. The Captured chronicled a long period of captivity, but did not appear to exceed a decade. Isaac’s Storm traced the initial development of Weather Bureau and covered a great period, but did not exceed that of The Polio Years. Several themes begin to emerge further into the book. Obvious themes included, the support for March of Dimes, impact on families affected by polio, the growth and development of rehabilitation facilities, and more importantly the response to the disease by Texans. Oddly, Wooten discusses the fact that other diseases such as, measles, diphtheria, and tuberculosis took more lives than Polio. However, people feared Polio more than the rest. Wooten attributes polio’s terrifying affect to the uncertainty. Several uncertainties such as, how to prevent it, why did some become crippled, why did some die, and why did it only essentially affected children made polio very terrifying in the 20th century. Texas appeared to have been hit the hardest in comparison to other states. Wooten’s research examined the time during and then after World War II. During this period, Texas saw an immense amount of polio contractions. Per

Polymyelitis, otherwise known as polio, was one of the most feared diseases of the early to mid twentieth century. This disease either killed or it paralyzed its’ victims. This affected America in such a terrible way by killing or paralyzing thousands of them within the beginning of the twentieth century alone, scaring most other Americans and putting up a red flag for most health organizations. President Roosevelt, however, conceived the idea of initiating the charity that would later

Poliomyelitis was a highly infectious disease that spread through many Americans in the early 20th century. As a matter of fact, over 3,000 Americans died of the disease each year. Families were overwhelmingly desperate for doctors to find a cure. When one suffered from polio, they generally experienced painful symptoms which included not only fatigue and muscle weakness, but even death. Therefore, when the polio vaccine was introduced by scientist Jonas Salk in 1953, it greatly contributed to Americans in numerous positive ways. Environmentally, the vaccine saved countless young American lives affected by the disease thus decreasing American mortality rates. Socially, the polio vaccine convenienced families who were either directly afflicted

On October 22nd, 2007 The United States Center for Disease Control and Prevention posted a web article which admitted that polio vaccines contained a cancer-causing virus. The United States Center for Disease Control and Prevention also known as the CDC, deleted the post within the week it was posted. The National Center for Biotech Information Center confirms that Micro biologist Maurice Hilleman discovered Simian Virus 40 was contained in polio vaccines administrated from 1995. (Hilleman) The CDC stated that the virus was removed from the vaccine in 1961. Records show that contaminated vaccines were used until 1963 and were used in different parts of the world until the 1980’s. (Varmus) As a result of the 98 million people given a polio vaccine; 30 million received the contaminated dose. (Hilleman) On May 10th, 2002 a Pathologist by the name of Dr. Michelle Cabone tested the

Not long after, President Franklin Delano Roosevelt who created the national foundation for infantile paralysis (NFIP) had himself paralyzed by polio too. He take this as a wakeup call and then began starting and organizing the massive research to test the effectiveness of polio vaccines which created by Jonas Salk. However, in order to that, require a lot of money, complicated procedures and not to forget, the subject to test the vaccines (Rebecca Skloot).

With a substantial amount of preventive healthcare advancements behind them, the American medical community turned its attention to the deadly polio virus plaguing America. From 1937 to 1952, known cases of Americans contracting polio skyrocketed from ten thousand to a staggering figure of roughly fifty-seven thousand cases. Of those cases within that time period, approximately one thousand five hundred deaths as a result of polio were recorded. In the year 1953, The National Foundation for Infantile Paralysis provided the scientist Dr. Jonas Salk with the tools necessary to research, and develop a working vaccine to combat the devastating polio disease. After much trial and error, Dr. Salk was finally able to create what he felt was a successful polio vaccination, and proceeded to conduct a field test. After resounding success, manufacturing instructions for the Salk vaccine were sent to a series of scientific laboratories for immediate production and administration to American children. The disaster that occurred next will forever be known through American medical history as the Cutter Incident (named so after one of the labs that administered the polio vaccine). This medical crisis sent shockwaves throughout America and the medical community, and numerous lawsuits were filed against Cutter Laboratories, resulting in fewer and fewer labs willing to accept contract work in developing vaccines.

Roosevelt became president with infantile paralysis (polio), which was diagnosed in 1921, and the public found out.9 Having the American people's president seem weakened by such a disease but push on through expectations showed that little to nothing was going to get in his way and stop him.10 Including FDR's case, close to 25% of those age 21 and older had paralytic cases by the early 1950s.11 Before the vaccine, there was a peak of about 50,000 cases of polio in 1953.12 Concern of the people was also around it's highest point due to the increasing risk of the horrid disease most feared at this time. Hopes for a solution were still going strong. Friends, family, and even strangers kept prayers for those in need. Anything that could be done was done until the vaccine was established. There were even several hundred thousand children placed in a control study and out of the 749,000, only 33 from the vaccinated group developed paralytic polio.13 In addition to this trial and other performed, and conclusion was drawn stating that the vaccine was 80-90% effective against the paralytic branch of polio.14 Chances for a new beginning were showing up all over with this vaccine, even if it only helped those who haven't been diagnosed

During the court case, Slater v. Baker and Stapleton (1767), physicians testified that it was customary for them to obtain consent from a patient prior to medical intervention (Mazur, 2013). In the United States, the term “informed consent” was first discussed in 1957 during the U.S. appellate court case, Salgo v. Leland Stanford Jr. University Board of Trustees (1957). At that time, the only standard used in informed consent was the professional standard until 1972 when the reasonable person standard was developed by Judge Spottswood Robinson during the landmark case, Canterbury v. Spence (1972) (Mazur,

David Oshinsky's 2005 Polio: An American Story, is a history of the fight to eradicate polio in the 20th century. Polio became one of the most, if not THE most, feared diseases of the century due to the influence and example of President Franklin Roosevelt, who was stricken with the disease as an adult in 1921. Owner of a Warm Springs, GA resort dedicated to polio rehabilitation(where he died in 1945), Roosevelt needed to raise funds to keep the resort operational. In 1934, he allowed planners to throw a nationwide series of birthday parties (over 6,000) for him to raise money for the care of polio survivors and for the upkeep of Warm Springs. The success of these parties and recognition that the key to raising money during the Great Depression

Franklin D. Roosevelt suffered from polio while he served as the President of the United States. Polio is a virus that causes paralysis, and can even lead to death. Before the polio vaccination was introduced in 1955, the virus had claimed thousands of victims over the years. (“Polio”). Today, vaccinations are available to the public in order to keep viruses like polio from causing an epidemic. A vaccination is the injection of a weakened disease or virus, in order for your body to build up immunity against a certain illness (Davidson). Vaccinations have become a controversial subject because of the side effects, the ingredients used and the idea of protecting the herd.

The discovery of the polio vaccine was an important medical and scientific breakthrough because it saved many lives since the 1950s. In the summer of 1916 the great polio epidemic struck the United states. By the 1950s hundreds of thousands of people had been struck by the poliomyelitis. The highest number of cases occurred in 1953 with over 50,000 people infected with the virus.

Polio is an infectious disease that has killed and paralyzed many people (Birth of Jonas Salk and the death of polio in India). It has taken the lives of

The similarity between the poliovirus and already solved plant virus’s led to a better understanding of how the poliovirus can regenerate within a host. Although the virus was similar to other plant viruses. The poliovirus was covered with more elaborate loops that are the site of monoclonal antibody escape mutations (Hogle, Chow and 229: 1358-1365Filman, Science). Individual proteins of the virus particle are produced by proteolytic cleavages from a larger precursor, yet the amino and carboxy-termini produced by proteolysis are very distinct. By noting this, Hogle and his team were able to conclude that proteolysis was not just making a lot of proteins from one gene, it is also controlling the timing of assembly (Hogle, Chow and Filman, Science 229: 1358-1365).