HPV Infection Case Study

What is the Human Papillomavirus? Commonly known as HPV, it is an infection that spreads through sexual contact. There are over one hundred different types of HPV; several types cause genital warts, while other high risk strands can lead to cancer of the cervix, anus, vagina, and penis. Because HPV is often asymptomatic, many people are unaware of their infection status, and thus, their potential for transmitting the virus to a sexual partner. The significance of the Human Papillomavirus is that fifty percent of Americans who are sexually active will contract it within their lives, and at any given point there are twenty million Americans already infected with it (“By the numbers: HPV Vaccine”).

HPV is so common in the United States that nearly all men and women will contract the virus at some point during life (Center for Disease Control and Prevention [CDC], 2017). In the United States, in 2008, it is reported that 3.2 million, or one in four adolescent women, ages 14 to 19 have had or have an STD (Kostas-Polston et al., 2012). The rate of HPV cases has only increased since 2008. The prevalence of a genital infection with any HPV type was 42.5% among United States during 2013–2014 (CDC, 2017). The incidence of HPV in the United States is about 14 million people each year.

They can appear on the vulva, in or around the vagina or anus, on the

The HPV virus has gone unseen by many until the recent controversy over the vaccine. However, this virus is thought to be one of the world’s most wide spread STD’s. “According to the Centers for Disease Control and Prevention (CDC), about 6.2 million women and men are newly infected every year” with HPV. HPV has over 100 strains, with more than thirty that are sexually transmitted. Some of these strains are known to cause cervix, vulva, vagina, anus, or penis cancers and others can cause genital warts. “Studies have found the vaccine to be almost 100% effective in preventing diseases caused by the four HPV types covered by the vaccine—including precancers of the cervix, vulva and vagina, and genital warts” (“HPV Questions and

The most common sexually transmitted infection (STI) is human papillomavirus (HPV) (CDC, 2013). Over half of sexually activity people will become infected with HPV at some point in their lifetime (National Cancer Institute, 2012). HPV can fall into two categories: low-risk HPV and high-risk HPV (National Cancer Institute, 2012). Low-risk HPV, also known as HPV types 6 and 11, cause about 90% of genital warts (National Cancer Institute, 2012). High-risk HPV, also known as HPV types 16 and 18, causes about 70% of cervical cancer (National Cancer Institute, 2012).

Prophylactic vaccination against high risk human papilloma virus 16 and 18 represents an exciting means of protection against HPV related malignancy. However, this strategy alone, even if there is a level of cross protection against other oncogenic viruses, cannot completely prevent cervical cancer. In some countries cervical screening programs have reduced the incidence of invasive cervical cancer by up to 80 percent although this decline has now reached a plateau with current cancers occurring in patients who have failed to attend for screening or where the sensitivity of the tests have proved inadequate. Cervical screening is inevitably associated with significant anxiety for the many women who require investigation and treatment following abnormal cervical cytology. However, it is vitally important to stress the need for continued cervical screening to complement vaccination in order to optimize prevention in vaccines and prevent cervical cancer in older women where the value of vaccination is currently unclear. It is likely that vaccination will ultimately change the natural history of HPV disease by reducing the influence of the highly oncogenic types HPV 16 and 18. In the long term this is likely to lead to an increase in recommended screening intervals. HPV vaccination may also reduce

Gardasil has been tested in thousands of women and found to be nearly 100% effective in protecting against diseases caused by the four HPV types. Side effects are very uncommon and the occurrence is about 1%. Not only are HPV vaccinations safe, and effective but in today’s society it seems that they have become necessary. “An estimated 493,000 cervical cancer cases occur each year with 274,000 deaths. More than 80% of cervical cancer deaths worldwide occur in developing countries. Cervical cancer is the second most common cancer in women”. If there is a cure of this kind of epidemic, it is evident that it is necessary.

There are many risk factors that put a person at risk for developing the HPV infection.

(Attention Getter) The Center for Disease Control reports that 100% of sexually active men and women contract genital HPV

Human Papilloma Virus (HPV) is the most commonly sexually transmitted disease in the United States. It is estimated that at least 80% of men and women acquire an HPV infection during their lifetime. “In a recent study of women in the United States 25% of fourteen to nineteen year olds were infected with at least one type of HPV. HPV is often acquired within a few months of sexual initiation, even among people with only one partner”. (Contemporary OB/GYN) Men are the main carriers of this infection but once a woman has been exposed to the infection she is also a carrier of HPV. Once a person has been

By limiting the number of sexual partners one has, getting vaccinated, and using condoms, one can significantly reduce his or chances of contracting a high risk HPV that can cause a cancer(1). A study in Australia has proved the effectiveness of the vaccine. Nathan Seppa in his article, “HPV vaccination proves its worth in Australia” states that, "Those who received all three shots were 54 percent as likely as unvaccinated women to have precancerous cervical growth and two-thirds as likely to have other abnormal cervical cell growth”(2). This demonstrates that there are steps people can take to prevent contracting HPV and in turn prevent cancers associated with certain HPVs.

There are 200 different strands of the HPV virus. Forty types are spread through sexual contact. The good news is that most people who contract the HPV virus will not have any adverse health effects. However, nearly all cervical cancer cases are linked to the HPV virus. Cervical cancer kills 3,710 women each year. The HPV virus can also cause oral cancer.

In recent years, medical experts and public health advocates have increasingly become concerned about the growing underutilization of the HPV vaccination in the United States. While most agree that the issue deserves attentions, consensus dissolves around how to respond to the problem. This literature review examines the background of HPV, several approaches to ensuring that HPV vaccinations utilized. This paper also compares effectiveness, for females ages 12-26, of strategies and of the only vaccination approved by the Food and Drug Administration (FDA) for long term prevention of HPV, as well as consequent diseases/illnesses.

Among the many arguments for mandatory HPV vaccination, the foremost is that it is an important medical achievement and a major public health milestone. This vaccine has proven to be one-hundred percent effective in preventing the 4 HPV strains that are responsible for seventy percent of cervical cancers and ninety percent of genital warts. In addition, no serious side effects have been identified. Because this vaccine is a preventive measure, administration before onset of sexual activity is ideal; however, even females who have been sexually active can still benefit from this vaccination (Perkins et al., 2010). Nationally and internationally, the HPV vaccine will significantly reduce disease burden by reducing monetary and psychological costs of invasive procedures that remove precancerous and cancerous lesions. By combining vaccination with routine Pap smear screening, these public health efforts have the remarkable opportunity to eradicate cervical cancer (Ramet et al., 2011).

Human Papilloma Virus (HPV) remains the most commonly sexually transmitted infection in both males and females. (Giuliano et al., 1999).