Examining the effective usage of hallucinogens in psychiatric research, its effectiveness in therapy and the risks associated with uncontrolled usage of hallucinogens.
Chantell Meltz
College of Science Technology and Applied Arts of Trinidad and Tobago
A drug according to Levinthal, (2012) is a chemical substance that, when taken into the body, alters the structure or functioning of the body in some way. Hallucinogen is a class of drugs which affects an individual’s perception, sensation, and emotions by disrupting the regular operation of certain neurotransmitters in the brain. While the use of Hallucinogens a form of therapy is a controversial topic and it does have it merits this paper examines the use of hallucinogens
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It is important to note that from the tens of thousands of doses of LSD and other classical compounds such as mescaline which has been conducted under medical administration, a general fact about these drugs have emerge which posits that the drugs are not addictive but is self-limiting meaning that if taken three days in a row it will no longer produce a psychic effect (Buckley, 1966). Studies on LSD have revealed that it causes no organic changes to the brain or any permanent changes in brain activity.
One must keep in mind that hallucinogens is classified as a schedule I drug in the Controlled Substances Act of 1970, which is reserved for drugs with a great potential for abuse, a lack of established safety even under medical supervision and no known use in medical treatment. This classification of hallucinogens as a schedule 1 drug has however not deterred the use of hallucinogens in psychiatric therapy and psychiatric research in the United States and around the world.
Dimethyltryptamine (DMT) another natural Psychedelic compound found in a wide variety of plants however the amount of alkaloid in the plants varies depending on the type of plant and the condition in which was grown and cultivated. DMT has been used since the 1990’s in many pharmacological studies at the University of Miami in research related to
The modern world’s first glimpse into the world of psychedelics was through d-lysergic acid diethylamide, or LSD. LSD was first synthesized in 1938 by two Swiss chemists from the alkaloid lysergic acid found in ergot, a parasitic fungus that grows on rye and other grains. Five years later, on April 19, 1943 Albert Hoffman, one of LSD’s co-discoverers
Chapter six talks about stimulants, like coffee (caffeine containing plants for the most part), cocaine, tobacco, and amphetamines. Many people would not consider coffee a drug, but those are usually the people that cannot go a day without it. Chapter seven talks about depressants, like alcohol, sleeping pills, narcotics, general anesthetics, and antianxiety drugs. Like coffee, many people would not consider alcohol a drug; it may be because it is legal but, when it is abused it has potential to cause more damage than many other drugs to one’s self and outsiders. Depressants depress the nervous system, reducing sensitivity to outside stimulation but in small doses they tend to make people relaxed and happy. The eighth chapter is about psychedelics, which are claimed to have the lowest potential for abuse of any of the psychoactive drugs. This chapter discusses drugs like LSD, morning-glory seeds, mushrooms, ibogaine, DMT, peyote, and ecstasy. People have been using hallucinogens since the beginning of time and most of these plants are concentrated in North and South America. The ninth chapter covers one drug only, marijuana. It is not a depressant or stimulant but has features of both, and some people even consider it a light psychedelic. The experienced high from marijuana can differ from person to person.
It has been shown that individuals turn to drugs that elicit a mood or level of arousal consistent with their mode of dealing with stress. Those who deal with stress by confrontation choose drug stimulants. Those who withdrawal from stress chooses opiate drugs. Others who deal with stress through activities related to imagery or fantasy turn to hallucinogens. These differences between behavior and drug preference are thought to be biochemically driven.
These substances are in turn broken down in the body into a great many more
The researchers conducted their study at the alcoholic unit of the New Jersey Neuro-Psychiatric Institute at Princeton, New Jersey. Participants were recruited by offering patients admitted to the institute the opportunity to take part in the experimental LSD program. A total of 28 alcoholics were admitted to the program, and their results were compared to that of a group of 34 alcoholics who took part in a standard comparison program provided by the Alcoholic Unit. Details about the patients were recorded such as their ethnic background, age, and marital status. Subjects were placed into groups of four. The first week was structured as an orientation week, and at the end of the week, two of the members were randomly chosen to be administered
Lysergic Acid Diethylamide or LSD is a hallucinogenic drug that can be taken orally, injected or even absorbed through the skin. Once LSD has entered the body, it starts to take effects on the levels of serotonin in the brain which can cause; hallucinations, mood change, and even sensory distortion. After taking LSD, the effects on the brain usually last from 6 to 9 hours depending on multiple factors; the dosage of LSD taken, the subject taking LSD, and even the user 's mood can affect the duration of LSD use. LSD is a non-lethal, non-addictive, and a non-habit forming drug that has little to no effect on the long-term health of an individual. However, LSD has been illegal since the 1960 's. Not only did availability of LSD become scarce with the criminalization of the substance, but the legislation also put a halt on the research of the chemical as well. Much of the way LSD interacts with the brain has been left unknown. This derivative from the rye fungus Ergot has been the source of controversy that has left many people wondering why LSD has been classified as a drug that is just as dangerous to use as heroin. It becomes difficult for an individual to understand how legislation could criminalize a chemical without completely understanding how it functions and affects people. LSD should be legalized for scientific, medical and recreational usage.
The growing debate over drugs and their use is a constant issue in today’s society. Animals and Psychedelics: The Natural World and the Instinct to alter Consciousness offers a unique look into how and why some people and animals have a natural instinct to seek out things to inebriate themselves. With the unique information this book brings to light, it creates new points for policy makers to take into consideration when drug policies are being created.
The article discusses research on the use of hallucinogens for medical therapies applicable to cancer, drug addiction, and psychological problems. Studies being undertaken at Johns Hopkins University are discussed. Johns Hopkins' research on hallucinogens includes assessment of the drug's psychospiritual effects among volunteers and its use in easing psychiatric and behavioral disorders in those so affected.
Thesis: There are many misconceptions about magic mushrooms, but I believe that they could be incredibly important for the future treatment of mental health.
Although the hallucinations caused by the drug are short, the effect is almost instant. DMT is passing through three barriers with the help of three different active transport mechanisms to be compartmentalized and stored within the brain.With this process, high intracellular and vesicular concentrations of DMT can be achieved within neurons. The outlined stages of uptake reveal that considerable physiological effort is exerted for the accumulation and storage of DMT and suggest that it has vital importance, since only a few compounds such as glucose and amino acids are known to be treated with similar priority. These extensive specialized processes would not have evolved to target a toxic compound or merely because of the psychedelic effects of DMT. DMT is a powerful and psychologically dangerous drug because the trip is so strong for such a short amount of time the user can actually lose sense of reality and experience seeing aliens or beings from another
While psychedelics can create a profound sense of distortion from reality urging the importance of putting yourself in a the right setting with the right people, there is little evidence that links psychedelics to toxic effects on the brain or body. So much so that researchers from the EmmaSofia organization in Oslo Norway claim that psychedelics are no more dangerous than common activities including playing soccer or riding a bike (Krebs, 2015). Psychedelic substances are known for altering your perception of reality, which could be dangerous if you’re somewhere that presents physical risks, but research suggests the psychedelics themselves do no damage physically. Not only are the psychedelics safe but they also provide therapeutic
It is no secret that drug use has the ability to completely alter a person’s state of consciousness, whether it be through extreme euphoria, increased hyperactivity, pain relief or psychedelic hallucinations. Although many drugs are used for medical purposes, the global issue of recreational drug use is now being fronted as an extremely serious matter that is steadily on the uprise. Recreational drug use is often associated with negativity, addiction and as having serious physical and mental repercussions. One of the few class of drugs that is often associated with both positive and negative connotations are hallucinogens, otherwise known as “psychedelics”, which have powerful altering effects on ones sense of perception, brain function
Drugs have been around for a very long time. They are used for a variety of reasons. Some of these reasons include relaxation, socialization, curiosity, stress relief, or a form of escapism. However, most people don’t know the threats and danger that it can cause to the body. In this paper, we are going to examine the changes that happen inside the brain due to the effects of different drugs. We will look closely at how drugs such as hallucinogens, ecstasy, cocaine, heroin, and cannabis affect an individual psychologically. I will explain the origin of the drugs, how a person feels while on the drug, how the drugs
Throughout the history of the human species, we have been always wanted to know three basic questions: why we are here, where did we come from, and where do we go after this life? Whether we were created from an omnipotent being as in many religions, we happened by chance and made it to where we are through evolution, or maybe even something else. Whatever the case may be, humans have always been curious and wondered about our existence and consciousness. Along with these age old questions, also came the use of psychoactive drugs and other mind altering substances. In order to try to understand these questions, humans have experimented with drugs that alter their state of consciousness.
An individual’s behavior and emotion becomes chemically altered often resulting in dependency, aggression, onset of diseases and poor judgement. This poses a dangerous threat to the neurotransmitters since they have multiple jobs in different parts of the brain. Drugs of abuse are able to exert influence over the brain reward pathway either by directly influencing the action of dopamine within the system, or by altering the activity of other neurotransmitters that exert a modulatory influence over this pathway. These drugs are often powerful and have been known to trigger schizophrenic behavior and can also cause a person to cease breathing, for example hallucinogens such as LSD, mescaline, and psilocybin are able to artificially stimulate the serotonin receptor (Sapolsky, 2005).