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Hashimoto Thyroiditis Essay

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Hashimoto’s thyroiditis is a common disease; it is also the most common cause of hypothyroidism. Some common symptoms are tiredness, weight gain, dry skin, cold intolerance, muscle weakness, and hoarseness. Hypothyroidism is treated with levothyroxine, but this medication does not help combat a major problem that patients have to deal with. Fatigue to some is not a big deal. People drink coffee, take caffeine, some take vitamin B12; but then there are patients that cannot shake the tiredness, the unwillingness to even get out of the bed, or even sleep disorders. This group of people had done research previously on patients with tiredness associated with ulcerative colitis. After this research they switched focus to other types of autoimmune…show more content…
These patients then answered a survey that evaluated their fatigue. They all had blood drawn to get baselines of their thyroid stimulating hormone, free triiodothyronine, free levothyroxine levels, thiamine, and thiamine pyrophosphate levels. The patients were then given dosages of thiamine based on their weight, two receive oral thiamine and one received an intramuscular injection every four to seven days. The three patient had repeat surveys throughout the process to evaluate any changes in fatigue severity. After twenty days repeat blood work was drawn and the last survey was given. This group of people doing the research concluded that the thiamine given for fatigue associated with Hashimoto’s thyroiditis rectified it completely in two out of the three and decreased the amount of fatigue in one of the three. Their hypothesis, that the chronic fatigue and related disorders accompanying Hashimoto’s thyroiditis were manifestations of a mild thiamine deficiency that could be due to either a dysfunction of the active transport from the blood to the mitochondria or structural enzymatic abnormalities likely caused by immune system factors (article
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