Have you ever met someone with Parkinson’s Disease? Typically when you learn about a genetic condition you have many unanswered questions. In this paper I will inform you on the biology of the disorder, the characteristics, and how having Parkinson’s Disease might impact a persons life.
When you analysis on this topic you will find that Parkinson’s Disease is a genetic disorder. This genetic disorder is very severe and can cause many problems to the brain. Parkinson’s disease occurs when nerve cells, or neurons, in an area of the brain that controls movement become impaired and die. A person’s brain slowly stops producing a neurotransmitter called dopamine. With less and less dopamine, a person has less and less ability to regulate their movement, body and emotions.
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Ths means that you will be able to identify if a person has this genetic disorder by looking at them. Some other characteristics are small cramped handwriting, not being able to walk or move from one place to another, and low voice volume. Loss of sense of smell, weight loss, and trouble sleeping.
In my opinion I believe that having Parkinson's Disease can affect a person’s life in many ways. One way it can affect a person’s life is that they may possibly only live up to anywhere between 10-20 years after being diagnosed. Having Parkinson’s Disease affects the way you move. It happens when there is a problem with certain nerve cells in the brain. Normally, these nerve cells make an important chemical called dopamine. Dopamine sends signals to the part of your brain that controls movement.
As you have read, there are many things to learn about Parkinson’s Disease. It is a genetic disorder and is evident at birth. Having this genetic condition can impact a person’s life by not being able to move and participate in a number of
Parkinson’s disease is a progressive disorder of the central Nervous system and affects both motor and nonmotor functions. parkinson 's is caused by a chemical imbalance within the brain. The brain produces a neurotransmitter called dopamine in the basal ganglia, which is structures linked to the thalamus in the base of the brain. If the Dopamine, Basal ganglia and Thalamus does not function properly then causes major damage,. A person having less and less dopamine, the individual has less and less ability to regulate their movements, body and emotions. Although there is no current cure available for Parkinson’s disease, the debilitating conditions can be lessoned through education, therapy, and a variety of treatments to improve their quality of life on the National Parkinson Foundation website.
Although the etiology of idiopathic Parkinson's disease (PD) is unknown, it is characterized by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) of ventral midbrain region [9]; [1]. Its prevalence is associated with age. Approximately 1% of the population is affected at 65–70 years of age, which increases to 4–5% in 85-year-olds [2]. Various epidemiological studies and pathological analyses have demonstrated that mean age of onset in sporadic PD, which accounts for about 95% of cases of Parkinsonism is 70 years [7]; [3]. Familial form of Parkinson’s disease is linked to genetic mutations and has prevalence rate of 4%. Familial Parkinson’s disease patients develop early-onset disease before the age of 50
Living with the disease causes impairment in many areas of the body. Motor impairment plays a big part in patients with Parkinson’s disease. The disease makes it hard to walk
Parkinson’s disease “is described as a common disorder of the brain caused by a progressive deterioration of the areas that produce the neurotransmitter dopamine” (Fischer, 1999). It affects the nervous system, more specifically it affects the nerve cells in your brain that secrete dopamine. Dopamine is a chemical that is responsible for the movement and coordination of the musculoskeletal system.
Symptoms are often hard for a doctor to assess, especially in the elderly because many of the symptoms show up in other common diseases such as osteoporosis and aging itself. The effects of Parkinson's Disease are often devastating. If not treated the disease can progress into causing total disability, and deterioration of all brain functions.
Parkinson disease (PD), also referred to as Parkinson’s disease and paralysis agitans, is a progressive neurodegenerative disease that is the third most common neurologic disorder of older adults. It is a debilitating disease affecting motor ability and is characterized by four cardinal symptoms: tremor rigidity, bradykinesia or kinesis (slow movement/no movement), and postural instability. Most people have primary, or idiopathic, disease. A few patients have secondary parkinsonian symptoms from conditions such as brain tumors and certain anti-psychotic drugs.
Parkinson's Disease affects the way the body moves, in the brain, there's an important chemical called Dopamine which controls movements that the body makes and sends signals to the brain to tell the body where to move. Having Parkinson's Disease, the nerve cells in the brain break down to where there isn't enough dopamine and have trouble controlling movements . Figure 1, shows a before and after picture of where in the brain the nerve cells which contain dopamine are located and how the nerve cells become damaged when a person has Parkinson's.
Author Lorraine V. Kalia wrote in The Lancet Journal on April 20, 2015 on Parkinson’s disease, she explains the fundamentals of the disease in which she highlights that the disease is more than a genetic disease but also influenced by environmental factors. Parkinson’s disease is classified as a neurodegenerative disease that affects motor functions in the body. It is caused from the death of dopamine producing neurons in the substantia nigra or the brain’s control center. The cause of the death of the neurons is still unknown; this makes the treatment and diagnosis of this disease much harder in the early stages. The death of neurons leads to a motor function It is diagnosed in the late stage that is accompanied by trembling, rigidity, slowness
Parkinson disease (PD) is a progressive neurodegenerative disorder characterized mainly by physical and psychological disabilities. This disorder was named after James Parkinson, an English physician who first described it as shaking palsy in 1817 (Goetz, Factr, and Weiner, 2002). Jean- Martin Charcot, who was a French neurologist, then progressed and further refined the description of the disease and identified other clinical features of PD (Goetz, Factr, and Weiner, 2002). PD involves the loss of cells that produce the neurotransmitter dopamine in a part of the brain stem called the substansia nigra, which results in several signs and symptoms (Byrd, Marks, and Starr, 2000). It is manifested clinically by tremor,
Parkinson’s Disease is known as one of the most common progressive and chronic neurodegenerative disorders. It belongs to a group of conditions known as movement disorders. Parkinson disease is a component of hypokinetic disorder because it causes a decreased in bodily movement. It affects people who are usually over the age of 50. It can impair an individual motor as well as non-motor function. Some of the primary symptoms of Parkinson’s disease are characterized by tremors or trembling in hands, legs and arms. In early symptoms the tremor can be unilateral, appearing in one side of body but progression in the disease can cause it to spread to both sides; rigidity or a resistant to movement affects most people with Parkinson’s disease,
Parkinson 's disease, also known as PD, shaking palsy, and paralysis agitans is an idiopathic neurodegenerative disorder; it rises from an unknown cause and increases in severity over time (Ronken). The disease was named after English physician James Parkinson, who first described it in 1817 (Weiner). PD can be defined as the degeneration of neurons in the substantia nigra, which is the area of the brain that contains dopamine cells and regulates movement. As the degeneration of neurons occurs, the brain loses the ability to generate body movement, which leads to the characteristic symptoms of PD (Weiner). The disease affects approximately 10 million people worldwide and is currently incurable (Weiner). Therefore, scientists have been
Like such a variety of maladies, Parkinson’s remaining parts a conundrum, regardless of our proceeded with restorative advances. It is dynamic, which implies it deteriorates after some time. There is no cure. We additionally don’t have the foggiest idea about its cause. There are, be that as it may, some treatment alternatives, including prescription and even surgery. The huge takeaways for what Parkinson’s is are:
Parkinson's disease is a disease that can very person to person. Some symtoms that can accur are tremor, slowed movements, ridgid muscles, impaired posture and balance, Loss of automatic movements, and speach and writting changes.
Parkinson’s Disease is incurable, and untreatable. Some people who have the Parkinson’s gene may want to know, and some patients may not want to know. Some may want to know, because they may want to be prepared for this condition, and make arrangements for their life when the symptoms come. They may also want to join drug trials to either help themselves or try to find a treatment for the future Parkinson’s patients. Although, some people may not want to know. They may not want to know, because they are afraid that it may affect the way they
Parkinson’s disease (PD), is a neurodegenerative disease of the brain affect nerve cells that associated with control normal movement and balance. The mechanism of PD start when loss of dopamine neurons that’s produced by nerve cells in substantia nigra . Dopamine is a neurotransmitter or chemical messenger that helps in transmission of signals between neurons in the brain . The etiology of PD is idiopathic, and it is supposed to be due to many risk factors such as, mutation in gene , age and exposure to some pesticides.