Historical Developments Relevant For Aspirin Essay

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Historical Developments Relevant to Aspirin:
A historical Development that relates to Aspirin is the father of our modern Medicine Hippocrates, who was a Greek Physician, left records of how they treated headaches, fevers and pains, and to ease child- bearing pains with a powder made of the leaves and bark form a Willow Tree. Also the Ancient Egyptians left a medical text called “Ebers Papyrus” which is also lists willow among a list a plant and animal remedies for pain relief, fever reduction, and as an anti-inflammatory. Also the Roman Celsus recommended Willow extract for treating the symptoms of Inflammations, swollen, red, feverish area, and pain. (Wikipedia “history”) This is relatable as the bark and leaves of the Willow tree are a natural resource of the Salicylic acid, which is found in Aspirin, which made the patients feel better while healing them, similar to the modern Aspirin. Further along in Human history we know that Edward Stone discovered and isolated the key chemical in the Willow bark/leaves called Salicylic Acid. The problem with the Salicylic acid was that it was extremely tough on stomachs and could cause nausea and vomiting, hence the next step in developing Aspirin was to find an effective buffer that would make the Salicylic acid easier for the stomach to handle, a French chemist named Charles Frederic Gerhardt was one of the first to attempt at creating a suitable buffer for Salicylic acid was to combine it with Sodium and Acetyl Chloride,

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