History Of Alzheimer's Disease

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I. Overview of Alzheimer’s Disease
Alzheimer’s disease is a progressive brain disorder and the most common form of dementia characterized by memory loss and disorganized thinking, problem-solving or language. Generally, Dementia is a decline in thinking, reasoning and remembering and two common forms includes dementia-Alzheimer’s disease and vascular dementia in which both are irreversible. Also, 60 to 80 percent of dementia cases are mostly Alzheimer’s disease. People with Alzheimer’s disease may experience a gradual impairment of intellectual abilities that is severe enough to interfere with activities of daily living. In a research done by Chang and Silverman (2004), Alzheimer’s disease is becoming a leading public health concern especially in people over 65 years old years old. And in United States alone, it is estimated to affect 4 million individuals and more than 30 million worldwide. Unfortunately up until now, there is still no cure for Alzheimer’s disease; however, there are promising research underway that targets the treatment of the symptoms.
II.
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History of Alzheimer’s Disease
In 1906, Alois Alzheimer discovered Alzheimer’s disease after he studied the dead body of patient August D. An autopsy was done and found fiber tangles in the brain that is now known as amyloid plaques. During the autopsy, there was shrinkage in and around the nerve cells noted in the patient’s brain. The symptoms that August D experienced before she passed away were memory loss, paranoia, and psychological changes. Currently, the main features of Alzheimer’s disease still includes presence of plaques, tangles and the loss of connections between nerve cells in the

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