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History Of The Influenza Virus

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Influenza virus has been causing recurrent epidemics of acute febrile syndrome every 1 to 4 years for at least recent centuries. The first epidemic report of the influenza like illness was noted in 1173-1174,1 but the first definitive epidemic was reported in 1694.2 The greatest pandemic in recorded history occurred in 1918-99 when approximately 21 million deaths were recorded worldwide.3 it was among the deadliest events in reported human history. After that Three others have occurred in the twentieth century: the 1957 H2N2 pandemic, the 1968 H3N2 pandemic and the 2009 pandemic influenza A (H1N1) virus (pH1N1). In the recent event an influenza strain with a combination of gene segments not previously reported in swine or human influenza virus

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