Hodgkin Lymphoma And Myeloma Essay

Who uses the sweetener or consume diet drinks may have heard of the controversy surrounding aspartame. The product has been linked with diseases or disorders such as migraine, multiple sclerosis, Alzheimer, cancer, lymphomas, and brain tumors, among others. This association is mainly caused by the fact metabolized in the human body-releasing methanol, a chemical compound that has toxic and accumulative effect on the nervous system. Despite being naturally present in small amounts in chicken in the meat, the beans and skim milk when ingested in large quantities methanol can cause blindness, among other problems. This fact has been known since the approval of aspartame in the United States, the Food and Drug Administration (FDA). However,

Page 1 Hello! My name is Alex. I am a nineteen year old girl who is about to bring you through my journey of a disease I never imagined would happen to me, well at least at this age. Three days into my nineteenth birthday I was diagnosed with Hodgkin’s lymphoma. If you don’t know what that means, as I didn’t the first time I was told it is the dreaded C word.

A couple of weeks after Hodgkin and Huxley achieved these results, Hitler invaded Poland. The two scientists rushed to publish their research in Nature and went their separate ways to help with the war effort. Although they would remain in contact, the two scientists would not meet in person again until seven years later (Schwiening, 2012).

This extended essay is trying to answer the question “How much does people’s knowledge of the affects of aspartame reflect the scientific facts?”. The essay starts with a brief introduction to the topic, explaining thoroughly what food additives are in general and furthermore what kind of substance Aspartame is. Before continuing to consider and discuss the dangers of food additives and aspartame, information about other sweeteners are researched and some examples of these are stated.

Therefore, aspartame (APM) in diet soda can lead to cancer and the risk of developing carcinogenic effects increase in those who have a life span exposure to APM.

In addition to the 52-week toxicity in infant monkeys, the 2010 Swiss mice study has also been cited in the general aspartame debate. Before this study occurred, previous lifespan experiments conducted on Sprague-Dawley rats have shown that aspartame exposure, starting from prenatal life, increases carcinogenetic effects in rats . This study aimed to validate aspartame’s link to causing cancer in rats . Furthermore, rodents—rats and mice—were used in this study because they, like primates, are one of the four super-orders of placental mammals . There were six groups of 62-112 male and female mice, which were treated with aspartame . They were fed at dosages of 32,000, 16,000, 8,000, 2,000, or 0 ppm from 12 days of conception to death . After

Cancers arising from the lymph nodes or other sites of lymphoid tissue are broadly termed lymphomas. This group of diseases is divided into Hodgkin’s disease and non-Hodgkin’s lymphoma. In both conditions, there is a replacement of normal lymphatic tissue by collections of abnormal lymphoma cells.

Stage 1: Hodgkin is discovered in only single lymph node part or lymphoid organ for example the thymus. Here cancer is located only in 1 area of an only organ outside the lymph system.

Aspartame is a chemical that is broken down into 3 different substances aspartic acid(40%), methanol(10%), and phenylalanine(50%). Of these compounds methanol is what raises the most questions when talking about aspartame because it is broken down into formaldehyde - a known carcinogen under long term exposure. “12 oz of fruit juice can have up to 5 times more methanol than 12 oz diet soda,” (American Chemical Society) yet no one criticizes on how juice is just as bad, if not worse, than that of diet

Aspartame in soda is considered safe as a diet drink according to the European Food Safety Authority. The review done by this agency confirms the safety of using aspartame sweetener in soda without any potential risk of cancer or damage to genes. It ensures its safety if consumed in the adequate levels of a diet drink. The safety concerns about aspartame in soda had led a fall in the sales of diet drink due to the presence of artificial sweetener that might cause side

Consumers themselves are figuring out that the ingestion of this chemical additive is at the root of their health problems. There have been over 92 different side effects associated with the consumption of aspartame. The multitude of this chemical additive’s side effects will base on one’s genetic individuality and physical weakness. According to Lendon Smith, M.D., there are an enormous number of people suffering from the side effects associated with aspartame, yet most of them do not have any idea why drugs, supplements and other medicine do not cure their symptoms. Headaches, weight gain, seizures, vision problems, and difficulty in breathing are only some of the symptoms of aspartame danger. On a more dangerous note, this chemical additive is proven to cause brain disorder and birth defects. It was revealed by Dr. Mercola of www.mercola.com that there are even studies being discontinued as soon as initial information confirms the damaging effects that aspartame brings. Moreover, the book While Waiting: A Prenatal Guidebook stated that aspartame consumption could put the brain of a fetus at risk. As for people who suffer from mood disorders, discoveries indicated that this artificial sweetener worsens the

The aim of this experiment is to determine the effects of consuming diet sodas containing aspartame and risk of developing cancers. Three types of blood cancers were considered in this research: leukemia and multiple myeloma and non- Hodgkin lymphomas. The participants used included 47,810 men aged between 40-75 years and 77,218 women aged between 30-55 years with no medical account of cancer. The regular diet of the participants was evaluated using a semi quantitative food frequency questionnaire (FFQ), which included measuring the consumption of diet soda. The results showed that the risk of developing multiple myeloma and non-Hodgkin lymphomas increased linearly for men, but not women, with an intake of 1 or more diet sodas per day. However,

Chronic Lymphocytic Leukemia (CLL) is slow-progressing or “chronic”, cancer of the blood and bone marrow. CLL is the second most common leukemia in adults and one of the four primary types of leukemia. Certain risk factors have been identified including age, race, sex, family history of blood and bone marrow cancers and chemical exposure. Most people diagnosed with CLL are white males over the age of 60. Occurrence increases with age and a marked increase after 60. Herbicides, insecticides and Agent Orange used in the Vietnam War have shown to increase the risk of developing CLL. There are approximately 15,000 new cases diagnosed each year.

Diabetic individuals are mentioned by scientist, Iyyaswamy and Rathinasamy, a number of times throughout the documentation of their study. The significance of diabetics to the study are not mentioned and readers of the article are left to wonder why in the introduction it is mentioned that the consumption of aspartame in diabetic individuals is on the rise. The writers reference diabetics again, in the conclusion, stressing the importance of creating awareness among those that consume aspartame and of the significant health risk that result from aspartame consumption. As one reads it is easy to pick up on the beliefs the scientist hold in regards to the importance of diabetics and their aspartame use. The obvious importance of these beliefs certainly could have been supported better throughout the text. It was confirmed by the study that oxidative stress is a byproduct of aspartame consumption. A diabetic’s cells are already affected by oxidative stress (Asmat Ullah, 2015, p. 4). A healthy balance is needed between free radicles and the antioxidants that neutralize them for the body to function properly on the cellular level. The balance of diabetics is affected more aggressively then healthy individuals

Many individuals and brands use them as a replacement for sugar, especially in diet products. However, there have been many claims of danger that could come from their use. Most of the blame comes from one key chemical, aspartame. Unfortunately, many claims lie rooted in rumor. Since artificial sweeteners are so commonly used, accepted, and approved in the United States, could they possibly be that detrimental? As of a 2004 study from the Annals of Oncology, there was no evidence that aspartame contributed to cancer. Unfortunately, the study refused to speak on the new forms of Artificial Sweeteners since it is too early to conclude any valid information (Oncology). However, a 2007 Research publication explained an experiment between mice and a consistent change to their diet. The end of this experiment provided evidence that artificial sweeteners, such as aspartame, can hold a carcinogenic effect. The mice had very visible tumor development and growth during this time period (Soffritti). Diabetes can also be an effect of artificial sweeteners. A 2014 journalist revealed the outcome of a study on the effects of artificial sweeteners on the stomach and how the glucose balance within the body can be thrown out of whack. Digestive and stomach microbes can be harmed by the artificial sweeteners that many products contain, even the ones that many diabetics rely on since they claim to be diet (ControversialStudy). The rumors and claims behind the danger of artificial sweeteners have developed through the years, however with multiple studies being conducted with varying results, no one answer can be given. Artificial Sweeteners will continue to be examined and studied, with the goal of finding an answer, but until then, a great amount of controversy will