How Aerobic Exercise Reduces Oxidative Stress And Improves Vascular Changes Of Small Mesenteric And Coronary Arteries

Cardiovascular disease is the number one killer in the United States, causing about 610,000 deaths yearly (Center for Disease Control and Prevention, 2015). Cardiovascular disease is defined as a group of disorders damaging the heart and blood vessels, usually involving the blockage of vessels, which in turn harm the heart (WHO, 2015). A 2011 American Heart Association statement predicted that without intervention, 40% of United States adults will have at least one form of Cardiovascular disease by 2030. A large portion of these deaths by cardiovascular disease is due to the sedentary population. To better prevent cardiovascular disease, the Physical Activity Guidelines for Americans Advisory Committee stated that adults should complete about 150 minutes of moderate intensity physical activity, or 75 minutes of vigorous intensity physical activity weekly (Barry, Blair, Church, Hooker, Sui, Warren, 2010). Research has shown that meeting these recommendations is linked with lower cardiovascular disease risk, as well as reduced risk of mortality. The Center for Disease Control and Prevention estimates that only about 20.3% of Americans meet these guidelines. These statistics show that the majority of the United States population does not get nearly the amount of physical activity they need. However, even though many people are not doing the recommended amount of physical activity, this may not mean that they are living a sedentary life. Living a sedentary lifestyle is

Effect of Exercise on Arterial Pressure and Vascular Resistance Abbie DeBerg Ms. Brantley May 30, 2012

Cardiac hypertrophy is the enlargement, or thickening, of the heart muscle. After lots of strenuous exercise the heart muscle will increase. If a person does exercise, a thirty minute jog every day, for six months there will be an obvious increase in many other factors but the heart muscles will have grown in size. These changes are reversible when you discontinue aerobic training.

The concern on whether anti-hypertensive’s should be withheld in patients who are hypertensive has been debatable in the recent past. Generally, the treatment of hypertension among hospitalized patients is basically an opportunity to enhance the recognition and treatment of blood pressure (Axon, Nietert & Egan, 2011, p.246). This is mainly because hypertension is a basic risk factor for heart diseases, stroke, and death whose impact is widespread to nearly 70 million adults in America. There have been numerous educational initiatives and publication of treatment processes to address this condition in the past few decades. Despite these measures, nearly 39 million Americans are at risk of hypertension because they have not reached their desired or optimal blood pressure.

Cardiovascular and metabolic diseases are a growing problem around the world today. Not only do diseases such as diabetes and heart disease affect individuals and their lifestyles, they also affect the economy, politics, education and the professional work environment. 20-26% of individuals in the United States live with heart disease, and obesity and high blood pressure compose the greatest factors for developing this disease [20]. Studies have shown a direct correlation between the amount of sedentary time and cardiovascular and metabolic disease risk, regardless of baseline measurements [20]. Thus, increase in physical activity will decrease cardiometabolic risk factors [8]. Several studies indicate a positive correlation between physical activity and decreased cardiometabolic risk markers [2,4,11,16]. However, we now know that an individual who is getting the recommended physical activity per day can still have a large amount of sedentary time.

Hypertension is a developing problem worldwide associated with an increased risk of cardiovascular morbidity and mortality. In 2020, the world population will be approximately 7.8 billion people, and there will be 1 billon people who may be affected by hypertension (Tomson & Lip, 2005). One in three adults in the United States has high blood pressure. According to the report “Health, United States, 2010 with Special Feature on Death and Dying,” the prevalence of hypertension among adults 20 years old or older increased from 24% to 32% during 1988-1994 and 2005-2008. The African-American population has a higher prevalence of this health condition than white Americans do. In 2005 to 2008, the prevalence of hypertension among black males (41.4%) was more than 10%,

The major health problem selected for this project was hypertension (Harrison et al, 2011). It is identified as a cardio vascular disease risk factor such as dementia, chronic kidney disease, coronary heart disease, and stroke (NICE, 2011). It can be missed easily, as in various instances it is asymptomatic as well as it is also known as a silent killer. The Hypertension is thought to be a disease of vascular regulation ensuing from arterial pressure control mechanisms malfunction (extracellular fluid volume, rennin-angiotensin-aldosterone system, and CNS) that results in elevation of BP by means of enhanced peripheral vascular resistance, and cardiac output. There are 2 basic hypertension types. Around 90 to 95 percent of the individuals have primary hypertension which is linked with change in lifestyle as well as needs medical treatment. On the other hand, 5-10% has secondary hypertension which is linked with various other diseases for instance pregnancy, thyroid, and renal (Haslam and James, 2005). It is estimated that around 1 in 20 adults will have increased BP of 160/100 mmHg and above that results in either more than one predisposing aspects (Gemmell et al, 2006).

Mayo Clinic Staff. (2015, June 20). Exercise and chronic disease: Get the facts. Retrieved from

The effects of exercise on blood pressure, heart rate, respiration rate and electrical activity of the heart were assessed. The measurements of respiration rate, pulse rate and blood pressures were noted as described in Harris-Haller (2016). Data was first taken from subjects in a relaxed position and then followed by sets of reading after exercising based on one minute intervals. The data also noted sitting ECG traces from Harris-Haller (2016). The respiratory rate, pulse, blood pressure, P wave, QRS complex and T wave were defined for each subject. The class average was calculated for males and females and graphed to illustrate the results by gender for each cardiopulmonary factor.

Good physical health is a vital part of the well-being of every person. A major component of our physical health is “Cardiovascular fitness”. Cardiovascular fitness is the ability of the heart and lungs to provide oxygen to the muscles for activity of an extended duration. If we have a good level of cardio-vascular fitness we are able to sustain activity for a reasonable period of time and not fatigue easily. This can give individuals a variety of health benefits and allow more regular and enjoyable activity to be participated in. This research report will examine my results of cardio-vascular fitness tests and weekly physical activity events, which

Physical activity has been proven to have phenomenal benefits on the human body and is an important part of a balanced lifestyle. Statistics have shown that regular exercise can prevent illness and lower one’s likelihood of being diagnosed with a series of diseases significantly. It has been ‘medically proven’ that regular exercise can reduce a subject’s chance of being diagnosed with coronary heart disease or stroke by 35%, type two diabetes by 50%, colon cancer by 50%, breast cancer by 20%, early death by 30%, osteoarthritis by 83% and a number of other life threatening illnesses. Regular exercise can improve a person’s overall wellbeing and immunity to common illnesses. During physical activity, a person’s heart rate can increase significantly and allow more oxygenated blood to be supplied to muscles. A person’s breathing rate can increase during exercise and supply more oxygen to the lungs. The increased blood flow during exercise allows the brain to function better. Exercise has many benefits to the human body and is a major factor of disease

INTRODUCTION: High-Intensity Interval Training (HIIT) is known as one method to treat Cardiovascular Diseases (CD), such as Coronary Arterial Disease (CAD) and Heart Failure (HF), due to its potential to improve cardio respiratory fitness (1, 15). This exercise format is characterized as aerobic exercise performed in a high intensity - usually controlled by either maximum oxygen uptake or maximum heart rate – with active and low intensity. Performing exercise in high intensities mixed with active rest allows patients to tolerate a higher effort before they become tired. Heart failure patients present a diminished exercise capacity, due to a smaller Ejection Fraction (EF), which tells us how well the heart pumps blood to body. To these patients, High-Intensity Interval Training has been reported for improving Systolic Function due to the increased effort in which the heart is working (16). The necessity to provide nutrients through circulation during exercise leads to an increased contractility and consequently LV Remodeling (15). Coronary Arterial Disease Patients have a decreased blood flow to the myocardial tissue due to an obstruction inside the coronary arteries. HIIT increases the arteriovenous O2 difference, which means there is an elevated consumption of oxygen by the tissues as result of a higher stroke volume. All those benefits have been shown in the literature, but most of the studies present data with short-term interventions. A few studies discuss the benefits

Approximately one in every three adult’s ages 20 years old and older are diagnosed with high blood pressure or hypertension. Hypertension affects 78 million people in the United States and is equally prevalent in both men and woman (Crabtree et al., 2013). Hypertension is a major risk factor for cardiovascular disease (Hajjar & Kotchen, 2003). It can lead to stroke, myocardial infarction, renal failure, heart failure, neurological issues, and death if not detected early and not treated properly (James, Oparil, Carter, & et al., 2014). Approximately 9.4 million deaths in 2010 were attributed to high blood pressure (Angell, De Cock, & Frieden, 2015). About 54% of strokes, 47% of coronary heart disease, and 25 % of other cardiovascular diseases are attributed to high blood pressure (Arima, Barzi, & Chalmers, 2011).

The benefits of physical exercise in humans far outweighs the harmful effects associated with exercise. A prescription of physical activity has been known to delay the onset or prevention of many chronic diseases. An improvement in heart function, lower blood pressure and improve functional capacity is noticed after just a few weeks of exercising. Physical activity will also result in an increase of lean muscle mass, promote weight maintenance, increased flexibility, and a generally stronger more fit individual. Conversely, exercise when preformed strenuously or obsessively can counteract such positive effects, bringing up some issues like oxidative stresses, injuries, and

The two major types of hypertension are primary and secondary. Primary hypertension accounts for more than 90% of all cases and has no known cause, although it is hypothesized that genetic factors, hormonal changes, and the altercations in sympathetic tone all may play a role in its development. Secondary hypertension develops as a consequence of an underlying disease or condition. The prevention and treatment of hypertension is a major public health issue. When blood pressure is controlled, cardiovascular, renal disease, and stroke may be prevented. The JCN, reported more than 122 million individuals in American are overweight or obese, consume large amounts of dietary sodium and alcohol, and do not eat adequate amounts of fruits and vegetables; less than 20% exercise regularly. Both modifiable and non-modifiable factors play a role in the development of hypertension