How Did Specific Germs Cause Disease

In the midst of the Industrial Revolution, the son of leather tanners provided the clarity needed to understand the behavior of microbes and applied this understanding to improve people’s daily life. This man, Louis Pasteur, succeeded in his medical investigations and continued to pursue his interest, despite objections given to him by his peers. The timeless work of Louis Pasteur in the areas of chemistry and microbiology provided the necessary foundation for the scientific study of immunology and stressed the importance of possessing a thorough understanding of the procedures involved in medical treatment.

Louis Pasteur was magnificently a genius. His life was an example of hard work and persistence. He was called “The father of modern hygiene, public health and much of modern medicine, as well as the father of microbiology and immunology.” As a scientist, he made many discoveries and experimentations that are benefits to human and animals. Although sometimes his claims raised controversies, Louis Pasteur investigated, revised deeper and deeper his claims to bring up more evidences that lead him to more and more discoveries. Today, because of his claims; we know the correlation or causation between putrefaction and fermentation. We know what makes the milk spoiled, and how to prevent people to overuse it by putting an expiring date on the gallon.

The introduction to the Rabies Vaccine had a great impact on the world. The man who invented the vaccine was Louis Pasteur. He had many specialties in his lifetime. Some of the areas of his interest were chemistry, biology and medicine. However, I believe his impact on the veterinary field was amazing.

“Louis Pasteur – Germ Theory of Disease” Inventors About. Com. 2014. Retrieved on January 13 2014 from Biography.com: http://inventors.about.com/od/pstartinventors/a/Louis_Pasteur.htm

In the late 1700’s, Edward Jenner published his work on the development of a smallpox vaccination. Nearly a century later, Louis Pasteur goes on to formulate the Germ Theory of Disease. Two years later, Pasteur goes on to create the first live attenuated bacterial vaccine for chicken cholera. Six years later, the rabies vaccination is developed by the same man.

He was inspired by the tales of milkmaids who already suffered cowpox and did not catch a severe case because their immunity was built to prevent further infection from cowpox. The first experiment was based off of this tale. He injected pus from a milkmaid’s cowpox pustule into a healthy boy and later discovered that when he injected the boy with smallpox a few weeks later, the boy did not become deathly ill. The same experiment was tested on a milkmaid who had not contracted either cowpox or smallpox, and the results were identical to the boy’s, which confirmed the effective use of the vaccine (Dr. Edward Jenner, "An

The intention of this paper is to examine the significant and enduring impact Louis Pasteur had on public health and wonderful advances in medicines and invention of vaccines. Louis Pasteur was a truly talented person who made many various discoveries in different areas of science. He invented Pasteurization, the process of treating milk free of damage causing microorganisms (Louis Pasteur, 2014). In 1843, Louis enrolled at the Ecole Normale Supe´rieure in Paris, where he focused in the origins of life. During the time he was professor in Strasbourg, France, he started investigating fermentation, which is a chemical process that breaks down organic substance. Pasteur became drawn to the field of transmittable diseases and the discovery of

Louis Pasteur's discovery of the relationship between germ and disease was only the beginning to developping a permanent solution. The theory led to the realization that handwashing helps prevent the spread of disease and disinfection can eliminate germs. Disinfection and handwashing affected humanity because the rates of infectious disease began to decline and epidemics lasted for a shorter time spand and overall mortality decreased as a result. The introduction of the theory affected how humanity viewed the human body. People began to believe that dirt contained microorganisms and could cause an infection, which lead to bathing frequently. Alongside his discovery were his inventions, for example the machine used to screen and detect silkworm eggs which saved the European silk industry and helped prevent silkworm

Louis Pasteur began his discoveries in the late 1800’s by discovering asymmetry as a sign of life. While studying fermentation processes, he discovered that yeast itself was a living process. Pasteur then found how to observe microorganisms, by isolating and providing a growth medium, impacting the future of biotechnology. His discoveries provided the future of wine, beer, vinegar and dairy industries. Pasteur wondered why milk and meat were getting sour or decaying, so he began to experiment. Anton van Leeuwenhoek gave Pasteur the curiosity to see if molecules just spontaneously appear. By exposing grapes to the air resulting in fermentation, Pasteur discovered that germs come from the outside world. This brought the discovery of germs, which

This saved the silk industry. Eventually, he applied his knowledge to the medical industry by asking doctors to sterilize their medical instruments by heating them to prevent the spread of germs. After two of his children died of typhoid fever, Pasteur wanted to know if there was a way to protect the body from germs. When an anthrax epidemic broke out among animals, he discovered that the anthrax bacillus was the carrier of the disease. By using the heating method he used to kill the yeast in food, Pasteur heated the bacillus enough to weaken it, and then he injected it into the animals to allow their bodies to build up a resistance against the bacteria. It worked, and Pasteur eventually developed a vaccine for rabies and other infectious diseases like cholera and smallpox. Pasteur had many questions that motivated his discoveries. Where are the micro-organisms coming from that cause fermentation? Can the fermentation process be stopped? If fermentation can be stopped in food, can that same concept be applied to protect the body from infectious disease? Then there was the motivation initiated through the

The work of Louis Pastor was included numerous discoveries in the medical field. This includes microbial fermentation, vaccines and pasteurization. In regards to vaccines it is states that Edward Jenner discovered the vaccination, while Louis Pastor invented vaccines. The motive leading to the first discovery of the vaccines dates back to 1879. At the time chickens were contracting a rampant disease, called fowl cholera that was spread throughout chicken coups. When a chicken was inoculated with the bacteria it would die but, when Pastor realized if a chicken was inoculated with old culture the chicken would become immune to the disease. Pastor discovered this by chance and then began to repeat this pattern

Louis Pasteur had 5 children, and 3 died from typhoid fever. Some say that this was what sparked his interest in studying cures for disease. Between 1804 and 1826, many scientists were studying rabies. They discovered that when saliva from a rabid dog was given to a normal one, and then to a rabbit and a hen, they were also infected. A man named Victor Galtier “demonstrated the transmission from dog to rabbit to rabbit, in series. He then immunized sheep by inoculation rabid saliva intravenously. This did not produce the disease, but interestingly, protected the animals from the effects of further inoculation.” This is what interested Louis Pasteur. He wondered if this meant that the disease was more infectious and rabid when passed from animals

This is a project of curiosity, I don’t have a super personal connection with this project and I don’t have a huge driving factor in making this project. I simply have always wanted to know how diseases have evolved to infect eukaryotes and counteract the immune system. I’ve always been interested in anatomy and the immune system fascinates me, it’s proof of a deadly race between the human body and the organism that seek to use it for their own purposes.

During the time of Louis Pasteur, a famous microbiologist, French animals and people were infected with a disease known as anthrax (Pasteur 59). Louis Pasteur was tasked with developing a vaccine, by the president of the Agricultural Society of Melun, to help the animals and people defend against anthrax. Pasteur outline and experiment that would be used to determine if the vaccine was truly working (Pasteur 60). The experiment involved sixty sheep where ten were left alone, twenty-five sheep received two doses of the vaccine, and the rest would mingle with other sheep in a hope to prove that the new sheep will be able to defend against the anthrax (Pasteur 61). After the experiment there hypothesis was affirmed as incoming sheep were able

Pasteur had already done work six years earlier with the disease chicken cholera, a disease that was to blame for the elimination of chicken flock in France. Through this one vaccine he produced for a single species of bird, he was able to discover the phenomena of virulence, or the harmful quality of a microorganism that causes the