How Do Scientists Visualize DNA

Understanding DNA can take a lot of studying and confusion to even get the general idea of the concept. The structure of DNA is very complicated and complex to understand, but researchers James Watson, Francis Crick, Maurice Wilkins, and Rosalind Franklin all developed the idea of the DNA structure in 1953. Deoxyribonucleic Acid is found in the nucleus of the cell. It is a double stranded molecule that contains the genetic code and is the main component of chromosomes. DNA is the blueprint of organisms. Nucleotides are the basic unit of DNA and they are made up of sugar, phosphate, and one of the four basis including adenine,

This paper explores the history and some interesting facts about DNA. The last couple centuries have seen an exponential growth in our knowledge of DNA. The history of the DNA can be traced back to multiple devoted scientist. This article attempts to summarize, and review the basic history of DNA while providing some fascinating information about it.

In the early 1950s, the race to find the structure of DNA was in full swing. The search was being conducted at three different colleges. At the California Institute of Technology, Linus Pauling,

Each human being has something called DNA. DNA is described as genetics and an extremely long macromolecule that is the main component of chromosomes and is the material that transfers genetic characteristics in all life forms. DNA constructs of two nucleotide strands coiled around each other in a ladder like arrangement with the sidepieces composed of alternating phosphate and deoxyribose units and the rungs composed of the purine and pyrimidine bases adenine, guanine, cytosine, and thymine. Each chromosome consist of one continuous thread-like molecule of DNA coiled tightly around proteins and contains a portion of the 6,400,000,000 basepairs that make up your DNA.

Structure and function in Biology is a broad concept that can be explored within a diverse range of topics across the subject matter. The following essay will be focussed mainly on the subject of Deoxyribonucleic Acid, or more commonly DNA. DNA is a highly complex, intricate and extraordinary macromolecule found within all living cells. DNA is a "biochemical noun" and can be defined as "...a self-replicating material which is present in nearly all living organisms as the main constituent of chromosomes. It is the carrier of genetic information." [Oxford Dictionary, c2016] DNA is found in the nucleus of eukaryotic cells, enclosed within a double membrane. Eukaryotic cells are multifaceted and require a high level of regulation to ensure smooth functioning. The double membrane of the nucleus allows gene expression, a key function of DNA, to be efficiently regulated.

Chapter 1: Genes can be demonstrated as “instruction books for making functional markers such as ribonucleic acid(RNA) and proteins”(Chapter 1, page 4). Distinctively, the four nitrogenous bases to code the gene of DNA is adenine, thymine, guanine, and cytosine. In addition, Rosalind Franklin was among the primitive people to experiment with X rays as a form of molecular photography in order to learn more about DNA and its structure. The structure of DNA taught a constitutional fact about genetics; it stated that the two strands of DNA were complementary to each other. Moreover, DNA replicates in order to make new sets of

within it. This packing is now known to be based on minute particles of protein

Who really discovered the structure of DNA? Though there were many scientists with contributions to understanding the structure of DNA one scientist stood out above all others; Rosalind Franklin. Although some people believed Watson and Crick made the most contributions to the discovery of the structure of DNA, I believe Rosalind Franklin made the most contributions. Rosalind Franklin was the scientist who took photos of DNA to figure out its form, proved phosphates are on the outside of DNA strands, and performed calculations on DNA to prove DNA’s structure. First, Rosalind Franklin was able to take photos of DNA that helped in the discovery of the structure of DNA.

DNA, Deoxyribonucleic Acid, is the basic structure for all life, it is the blueprint, the instruction manual, on how to build a living organism. DNA is made up of four nitrogen bases, adenine, thymine, cytosine, and guanine which are connected by sugar-phosphate bonds. Through a process called Protein Synthesis, the nitrogen bases are the code for the creation of amino acids. Essentially, DNA makes amino acids, amino acids make proteins, proteins make organisms. This process has been taking place for much longer than scientists have been able to document. Those scientists are called geneticists and their field is genetics.

DNA is a long curved structure, made up of pairs of four specific bases: adenine, guanine, cytosine, and thymine, is the repository of a code from which all of our cells are made. The code is made up of base pairs which look like the

Deoxyribonucleic acid, commonly known as DNA, was first discovered by Johann Mieschere, a Swiss biologist, in 1869. He made the discovery while studying the nuclei of leukocytes, however the greater significance of this molecule and its structure would not be known until 1951. At that time, scientists did not know the function of DNA, let alone the structure. It was believed that the structure of the mysterious molecule would help uncover its true function. The structure of DNA was solved by James Watson and Francis Crick at the University Of Cambridge, England. They deduced that DNA was made up of chains of nucleotides with one of the four different bases: Adenine, Thymine, Guanine and Cytosine on the inside and its phosphate backbone on the outside, thus creating the double helix. This discovery could be considered the single most important finding that gave rise to the study of heredity and gene expression. However, Watson and Crick could not have revealed the three-dimensional structure of DNA without the previous contributing research conducted by Erwin Chargaff, Phoebus Levene, and Rosalind Franklin.

The study of deoxyribonucleic acid, better known as DNA, sounds modern, but in reality has been around for over 150 years. In 1856, Gregor Mendel performed his famous pea plant experiment. This experiment helped determine dominant and recessive traits. Mendel’s work faded for more than 30 years. Based on his research, Reginald Punnett developed Punnett Squares. Punnett Squares predict which traits offspring will inherit based on their parents. In 1885, scientists found chromosomes in cells.

Deoxyribonucleic (DNA) is the molecule that hold the genetic information of living things. In our body every cell contains about 2 meters of DNA. DNA is copied every time a cell divides. Deoxyribonucleic (DNA) is made up of two polynucleotide strands. Polynucleotide strands twist around each other, forming a shape that looks like a ladder called a double helix. The two polynucleotide strands run antiaparallel to each other with nitrogenous bases this means that the stands run in opposite directions, parallel to one another. The DNA molecule consists of two backbones chains of sugars and phosphate groups. The organic bases held together by hydrogen bonds. Although bases bonded together are termed paired

Rosalind Franklin’s work on DNA was crucial in discovering the composition of the human body as a whole. Her x-ray photo revealed a double helix structure and she also discovered the A and B form of DNA. She worked through the adversity of being a female in a predominately male dominated realm and made remarkable findings that were eventually stolen. She adapted to a new lab with antiquated technology. Before this discovery, the structure of DNA was thought to be simple. Scientist, Watson and Crick, started with the wrong structure of DNA from a misinterpretation of notes from one of Franklin’s presentations. Unlike Watson and Crick, Rosalind Franklin could explain DNA and how it worked.

Due to the DNA’s specificity, samples can be utilised for identification. DNA is a nucleic acid composed of deoxyribose sugar bound to a phosphate group and one of four nitrogenous bases (adenine, guanine, cytosine and thymine). Each section of these three components are referred to as nucleotides, which are joined to the phosphate or sugar of another nucleotide by strong covalent bonds to form a backbone. The nitrogenous bases are joined to complimentary bases of another nucleotide (adenine with thymine, guanine with cytosine) to create a double stranded molecule (Figure 2). To complete the double helical structure, the molecule coils to compact it’s contents. DNA molecules can contain up to two million base pairs, with a human genome containing approximately 3 million base pairs. The random assortment of nitrogenous bases as well as the numerous mutations within certain DNA sequences, results in genetically diverese DNA molecules and genomes between individials.