How Does Gene Mutation Cause Breast Cancer?

of an improperly regulated cell cycle. Name two reasons why cells can form tumors. A mutation can cause cells to become unable to differentiate and subsequently pile up. Damage to tumor suppressing genes can cause tumors to form. Oncogenic mutations can cause excessive cell division causing the formation of tumors.

It can mutate in many ways, but truncating mutation types are associated with the greatest incidence of breast cancer because since DNA repair functions are not functioning properly, other mutations of fast-replicating cells go unchecked and allow for aggressive tumor growth. BRCA2 is the next type of tumor suppressor gene, located on chromosome 12q12 and is also involved with DNA repair, and also result from truncated proteins. BRCA2 mutations account for 35-40% of all BRCA gene mutations, and 28-32% of all hereditary breast cancers. So, what do breast cancers actually do? For starters, we have cytokines that mediate intracellular communication locally to cause an integrated response to stimuli. These can be synthesized be healthy or diseased cells, and their job is to regulate survival, growth, differentiation and effector functions of the cell. In breast cancer, many cytokines have a role in expression of cancer cells and are usually produced at the site of the tumor. The certain suppressive cytokines may inhibit the immune response against tumor cells and will inhibit the functions of lymphocytes that are associated with tumor suppression and may in turn actually promote tumor growth. There is a category of cytokines that are

This type of breast cancer begins in the milk ducts of the breast. At first, there are normal cells, but then a mutation occurs. Some kind of carcinogen damages and changes a couple of genes. The mutated genes associated with breast cancer are Genes BrCA1 and BrCA2. The

Our bodies are made up of millions of cells that contain the code of our genetic makeup. When the genetic code of a normal cell breaks, it causes that normal cell to transform its normal behavior. Cancer occurs when these damaged cells continue to form, gather together and begin to invade the normal tissues in the human body. Broken, damaged cells that begin in the breast tissue is identified as breast cancer. (Link, 2012, p. 9-11)

Basically, breast cancer happens when the amount of cells growth exceeds the amount of cells which die. Ultimately, they are out of control and being spread to other parts of the body, including the liver, bones or even the brain. There are many factors which contribute to

Cells are constantly getting instructions from chromosomes to divide. Cancer forms when cells get instructions incorrectly and begin dividing too much and cells do not get a message to stop making cells so they continue to divide. When cells grow out of control, a tumor forms. A tumor that is malignant does spread.

What is Breast cancer? Cancer is caused when a cell turns cancerous. When a cell in the body is mutated the DNA within the cell is damaged, causing the cell to stop its traditional function and allowing the cell to become cancerous. When the cell in the breast mutates and turns cancerous, it leads to breast cancer. The cancerous cell grows into a tumor. Breast cancer has not been so prominent in Australia for the past few decades, yet, it is more commonly occurring

According to breastcancer.org, breast cancer is the uncontrolled growth of breast cells and also referred to as a malignant tumor. A malignant tumor has the potential to be dangerous and can eventually spread beyond the original tumor to other parts of the body. Breast cancer usually originates in the cells of the lobules, which are milk producing glands, or they can also begin in the ducts, which are openings that drain milk from lobules to the nipple (breastcancer.org). After time, the cancer cells attack neighboring healthy breast tissue and make way into

Breast cancer is a very common disease in women. Simply stated, cancer that forms in the breast cells is breast cancer. Breast cancer appears when the breast cells start growing and dividing too fast. The cells begin dividing faster then the normal cells and a lump or mass is formed (Breast Cancer). Some of these tumors, though, are benign; these tumors are not cancerous and do not spread throughout the body. Other tumors are malignant; they are cancerous and able to spread throughout the body (Braddock 3-4).

Breast cancer is a form of cancer that develops within the cells of the breast tissue. This type of cancer is more common in females as breast cancer is sensitive to the estrogen hormone; however, males can develop breast cancer as well. A cause of breast cancer has not been found and it is not well understood why some develop breast cancer and others do not. However, breast cancer risk factors include age, genetics, a past history of cancer, dense breast tissue, obesity, alcohol consumption and radiation exposure to name a few.

Cancer is a genetic disease, which means that the disease is caused by changes in our genes. These changes can be caused by environmental factors, can be familial, or can be passed down from parents, and the changes mutate DNA so that cells do not divide in a normal fashion.

According to the American Cancer Society, Each year, more than 200,000 women are diagnosed with breast cancer; furthermore Twelve percent of all women will contract the disease, and 3.5% of them will die from breast cancer (American Cancer Society, 2005). There are risk factors that may lead to breast cancer. There are 4 stages of breast cancer and several treatments, although treatments vary from types and stages of breast cancer. Breast cancer is the leading cause of death among women who are 40 to 55 years old (Breast Cancer, 2009).Cancer occurs when cells divide uncontrollably. It changes from a normal cell to cancerous cells that require gene alterations. Therefore the altered genes and the uncontrolled growth may lead to tumors.

One out of eight women around the world develops the most common disease called Breast Cancer. In the United States, about 200,000 women suffer from this disease and it causes more than 40,000 death each year. Breast cancer is a cancer cell (malignant tumor) that forms in the breast. The cancerous cells grow in the breast and then invade the healthy cells and the surrounding tissues of the breast and it can also spread into other parts of the body. Breast cancer is more common in women but men can also get it too. One of the reasons that males are less likely to develop breast cancer because males have less estrogen and progesterone hormones which is a higher risk of breast cancer cell to grow. There are many risks factors that can cause

The main cause of the carcinogenesis in the breast is estrogen along with mutation of the gene further metabolism of it, and growth of the tissue is provoked.

Cancer is a disease that occurs because of a gene that has an abnormal gene function. Genes do many wonderful things in your body such as tell you when to get rid of dead cells, control your skin and hair color, and can also affect your chances of getting certain diseases, like cancer. Every cell in your body has a copy of every single gene that you have, even though they may use different genes. An abnormal change in a gene is called a mutation, there are two ways to get a mutation. You are either born with this mutation or you acquire it.