How Does Huntington's Disease Affects The Brain

Fragile X Syndrome is a genetic condition. FXS causes learning and behavioral challenges, intellectual disability as well as a variety of physical characteristics. Although Fragile X Syndrome can occur in males and females, males are affected more frequently than females are; furthermore, males with FXS generally experience characteristics with a greater severity than females with the condition do.

Fragile X Syndrome is a genetic condition causing intellectual disability, behavioural and learning challenges and various physical characteristics, it occurs in both genders but effects males more. Also is the most common gene for Autism worldwide, every week in Australia one child is born who is fully affected and 20 children are born who are carriers. It is estimated that 5 per cent of people with a diagnosis of an Autism Spectrum disorder also have Fragile X.

Huntington’s disease destroys the organs that carry the functions of the central nervous system. Kalat (2013) states, “Huntington disease (also known as Huntington disease or Huntington’s Chorea) is a severe neurological disorder that strikes about 1 person in 10,000 in the United States” (A.B. Young, 1995, p. 258).Individual’s develop the symptoms in their middle age, but even if it is a rare disorders juveniles as well as children before the age of ten can develop the disease. Huntington’s disease is hereditary disease that is passed on from a parent. Huntington’s disease is of the lack of the chromosome 4, if one of the parents carries the gene, they can pass that gene to their

The gene is mutated and it affects more males than females. Individuals with Fragile X have a large number of defects and disabilities including physical, cognitive, and neurobehavioral features (Jewell, J., 2004). This disability is caused by a gene that inactive which is the X chromosome. There is no known cure, yet, options are available to those who have this disorder. Individuals may receive speech therapy, physical therapy, and psychological services. For children attending school they may qualify for special education. Delays in cognition and learning are often associated with this syndrome. That's why; learning can be more challenging for these individuals. The impairments differ for those impacted with the syndrome. Accommodations are essential in order to meet the needs for each

Huntington's disease is caused by an inherited defect in a single gene. Huntington's disease is an autosomal dominant disorder, which means that a person needs only one copy of the defective gene to develop the

Fragile X syndrome (FXS), often referred to as Martin-Bell syndrome, is an inherited genetic condition, associated with intellectual and emotional disabilities ranging from learning problems to mental retardation, and mood instability to autism, especially in boys. In addition to intellectual disability, there are distinguishing physical features as well, including elongated face, protruding ears and low muscle tone

Affected males inherit a fragile X chromosome that had not been silenced in the previous generation by a cycle of maternal chromosome inactivation and incomplete reactivation.

In 1943 two men, Martin and Bell discovered a gene condition called Fragile X Syndrome. 2 Fragile X Syndrome (FXS) is a genetic condition, which may cause an intellectual disability, behavioural and learning difficulties and various other physical characterstics.1 It occurs when the female gene (X-gene) is repeated over 50-200 times, this is called Fragile X permutation. 1 In 1969, Herbert Lubs established the chromosomal test for Fragile X Syndrome. Fragile X Syndrome is an inherited condition in which the X chromosome is passed on from the parent to the child. If the woman has the affect X, they will have an increased chance for passing the gene on but as men have an Y as well as an X chromosome, if they have Fragile X Syndrome, their sons won’t be affected as they have their fathers Y chromosome. It is the most common form of inherited intellectual disability in males and a major cause of intellectual disability in females.

Adolescents at risk for Huntington’s Disease should undergo predictive genetic testing to maximize their enjoyment of life as a healthy individual. Although fatal, Huntington’s Disease is not an immediate death sentence. People can usually continue to function normally for many years if the disease is diagnosed in adolescence. Testing for Huntington’s Disease can end uncertainty and allow adolescents to make informed decisions about the rest of their lives in order to make better use of the time that they have as a healthy person.

Huntington’s Disease is a genetic disorder characterized by the arrival of symptoms late in life, usually in the 30s or 40s. It is an autosomal dominant disorder, which includes nerve cells breaking down in the brain. There are both movement and cognitive symptoms related to this disease. Some movement symptoms are unintentional jolting, delayed eye movements, and a compromised manner of walking. Some cognitive symptoms are trouble organizing responsibilities, a deficiency of cognizance of one’s own actions and capabilities, and a difficulty in understanding fresh material. There are also psychiatric disorders associated with Huntington’s disease: depression, obsessive compulsion disorder, and mania. Huntington’s disease results from a mutation

Huntington 's Disease (HD) is a progressive brain disorder caused by a defective gene. This disease causes changes in the central area of the brain, which affect movement, mood and thinking skills. Nerve cells become impaired, causing several segments of the brain to fail. The disease disturbs movement, behavior and perception the affected people abilities to walk, think, reason and talk are slowly weakened to a point that they eventually become entirely dependent on other people for care. HD is a disease that affects the brain in many different ways. One of the ways the HD affects the brain is that it causes the person who has it to become forgetful and moody. Huntington 's disease also causes a decline in thinking and reasoning skills, including memory, concentration, judgment and ability to plan and organize.

Fragile X Syndrome is a genetic disorder caused by changes to the FMR1 gene. The FMR1 gene creates a protein that is necessary for normal brain development and it is located on the 23rd chromosome (which makes it X-linked dominant). It affects both females and males, but it is more likely to occur in males and typically presents more severely in males. It is estimated at 1 in 4000 boys are affected, while 1 in 8000 girls are affected. Most males and around half of females present with physical characteristics; long and narrow face, large ears, prominent jaw and forehead, flat feet, and low muscle tone, all of which become more apparent post-puberty. It causes a range of developmental disabilities, from learning disabilities to more serious

Huntington’s disease is a neurological (nervous system) condition caused by the inheritance of an altered gene. A neurological disorder is a disease that can affect the central and peripheral nervous systems. Huntington’s disease is an incurable genetic brain disorder. The disease is an autosomal dominant disease, meaning a child only needs to inherit the gene from one parent to develop Huntington’s. Nerve cells become damaged when someone holds the HTT gene that produces a protein called huntingtin, as too much of this protein damages cells, and causes various parts of the brain to gradually deteriorate. Huntington’s disease causes changes in the central area of the brain, the basal ganglia, which can affect movement, emotions, and mental

Fragile X Syndrome (FXS) also known as , the Martin-Bell, or the marker x syndrome. This genetic disorder is an autosomal dominant. It is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Majority of the time males are in more risk than females to getting this genetic disorder. For more proof of this fact statistics say that 1 in 4,000 males and 1 in 8,000 females tend get this disorder.This disorder is caused by the expansion of lengthening of FMR1 gene on the X chromosome. When it lengthens it turns off the production of a protein that is involved in brain development and other functions. This Fragile X gene can be passed down through generation.

I had heard of Huntington’s disease before I read this book, but I did not really know much about it I know now what a destructive disease it is. The book revolves around two main characters in the book Joe O’Brien who is a police officer, father to four children and husband to Rosie. The second character the book focuses on is the youngest child Katie O’Brien. The read first tells about Joe and how his life starts to unravel due to the disease. The author does a stupendous job describing what Huntington's is through this character by how it affects him physically and mentally. Therefore, destroying each fragment of him a piece at a time. You grow to care about the characters making it an emotional book but, the O’Briens have a special strength