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Parkinson’s disease is a progressive neurological condition which occurs when the brains nerve cells that contain/produce dopamine die, without the chemical

Parkinson’s disease “is described as a common disorder of the brain caused by a progressive deterioration of the areas that produce the neurotransmitter dopamine” (Fischer, 1999). It affects the nervous system, more specifically it affects the nerve cells in your brain that secrete dopamine. Dopamine is a chemical that is responsible for the movement and coordination of the musculoskeletal system.

PD is the second most common neurodegenerative disease featured pathologically by the progressive loss of dopaminergic neurons in the substantia nigra. The typical symptoms of PD include slowness of movements (bradykinesia), muscle stiffness (rigidity), tremor, and balance disturbance. Etiopathologically, PD is considered to be caused by the significant loss of dopaminergic neurons in the substantia nigra pars compacta and the subsequent dopamine depletion at the striatum. To date, there are only symptomatic treatments available for PD, particularly in the early stages of the disease. No therapy has been found that can cure or halt the progression of the disease.

Parkinson Disease (PD) is a neurodegenerative disease symptomized by tremor, muscular rigidity, and slow imprecise movements. Typically, the disease affects middle-aged and elderly individuals. PD is associated with degeneration of the basal ganglia of the brain causing a deficiency of the neurotransmission of dopamine.

As a neurodegenerative brain disorder, Parkinson’s disease affects the neurons in the human brain. This disease affects everyone differently. However, there are common symptoms that all patients with Parkinson’s experience. At this time, there is no cure for the disease, but there are several ways to improve the quality of life. Although research is never complete, there is a lot of information on Parkinson’s disease that individuals should know.

“The disease is caused by the death of cells in one of the movement control centers of the brain” (Sick!). More than one million people in the United States are affected by this disease, and about 60,000 new cases are diagnosed each year with an equal frequency and men and women. It usually develops when a person is in his or her late 50s or early 60s. Parkinson's Disease develops gradually, but continues for long periods of time, usually many years. When brain cells die in the substantia nigra, it doesn't release enough dopamine. Dopamine is a neurotransmitter that helps send signals that control movement, and without it, signals cannot travel from substantia nigra brain cells to other parts of the body. This makes every day movement like walking and writing to not occur correctly. Researchers have not yet discovered the basic cause of Parkinson's disease, but some think the disease is hereditary or caused by environmental factors. Some of the symptoms of Parkinson's Disease are tremor (shaking), slowing down of movements, muscle rigidity (stiffness), problems with posture and balance, depression, changes in the way a person speaks, sleep problems, emotional changes, incontinence (loss of bladder control), changes in handwriting, and dementia (problems with mental functions). There is no known treatment or way to prevent Parkinson's disease

Parkinson’s disease is a chronic disorder of the nervous system with a gradual onset that primarily affects the body’s motor system. The symptoms of the disease are mainly caused by the death of dopamine-producing cells in the midbrain. Dopamine is an important neurotransmitter that, among other things, is responsible for playing a role in how the brain controls bodily movements. Therefore, the cardinal symptoms of the disease are movement related, including tremor and rigid, jerky movements. Parkinson’s is a progressive disease, meaning it gets worse over time, until it eventually leads to complete disability. Parkinson’s is a fairly common disease, and several well-known people, such as actor Michael J. Fox and boxer Muhammad Ali have

Parkinson’s Disease (PD) is a nervous system disorder that affects nearly five million people world wide. Most of the effects of PD are movement based. It is more prevalent in men and the chance of developing the disease increases with age. Fifteen percent of those with Parkinson’s have been identified as having a family history of the disease. Those who are 80 or older may be one-thousand times more likely to develop PD than those under 40 (Jankovic & Tolosa, 2015). The symptoms of PD were first described in 1817 by James Parkinson. Over time, Parkinson was able to observe the disease in six different patients, seeing the similarities in their symptoms. As sciences have advanced at a rapid rate, the understanding of PD has

It has been proven that a set diet and forms of rehabilitation like exercise can improve symptoms of parkinson’s disease. When the drugs become ineffective sufferers of parkinson’s can undergo surgery to place microelectrodes for deep brain stimulation which reduce motor symptoms. Other symptoms which aren’t as big an issue like sleep disturbances and emotional problems can be effected by the medication that is taken. Sleep disturbances can be worse and somebody with parkinson’s can also suffer sleep insomnia, 13% of people with parkinson’s have sleep attacks or narcolepsy which is a neurological disorder which makes a sufferer randomly fall

What is Parkinson’s disease? Parkinson’s is a progressive condition by a loss of never cells in the brain known as neurodegeneration. The cause of neuronal loss in Parkinson’s is still unknown. However, the symptoms can still be explained by the loss of cells that contain neurotransmitter called dopamine. Dopamine is a type of chemical that nerve cells release to communicate with other nerve cells. It is just not responsible for doing that, dopamine has many other functions it must do including important roles in behavior, voluntary movement, motivation, sleep, mood, attention, working memory, and learning. So, in Parkinson’s the neurons that produce dopamine slowly start dying. When dopamine levels get, lower this will cause an imbalance with the other neurotransmitters and will result with confusing both motor and non-motor symptoms which will get worse overtime. (Sethi 2002) Parkinson’s is a really known disease as Alzheimer’s it is said that there is an estimated number of up to 1.5 million Americans suffering from the disorder at any given time. (Mayo Clinic Staff, 2015)

About one million Americans and four million people worldwide suffer from Parkinson’s disease. The number of individual’s with Parkinson’s increases by at least sixty thousand per year in America. Although the Parkinson’s disease has been around for thousand of years, it was not officially recognized until 1817 by a Dr. James Parkinson. Dr. James Parkinson clearly stated in his paper An Essay on the Shaking Palsy symptoms of Parkinson’s that are still recognized today as markers for the disease. Even though he wrote that paper in 1817, it was not until 1861 that the medical community began to collectively look into this debilitating disease.

Parkinson’s is a very interesting disease because just like there is no set cure or cause, there is no one way diagnosis for the disease as well. However, doctors take into consideration the many symptoms that are typically present in someone

Parkinson’s disease has been known about since ancient times. In AD 175, the physician Galen described it as “shaking palsy” in Western medical literature. It wasn’t until 1817 that a London doctor, named James Parkinson, wrote a detailed medical essay on this disease. This essay established Parkinson’s disease as a recognized medical condition. He based the essay off of six cases he had observed previously and hoped that it would encourage others to study the disease. No such research was performed until finally, sixty years after Parkinson’s essay was published, a French neurologist named Jean Charcot studied the disease and was the first to truly recognize the importance of Parkinson’s work. As a result, he named the disease after him. Much has been learned about the disease since then; however, much of it still remains a mystery. Researchers have learned that the symptoms for this disease are progressive, degenerative, and tend to occur more in older individuals. It has been found that a dopamine deficiency of the brain is the root of the matter; although, why this initially occurs is less clear. The Parkinson’s Disease Foundation was created in 1957 to assist those who are suffering and promote and fund further research. Since the 1960’s research has only progressed more and more rapidly. Even though there still is no known cure, the symptoms can now be effectively controlled and reduced in severity. Moreover, many other foundations assisting the cause have been

Author Lorraine V. Kalia wrote in The Lancet Journal on April 20, 2015 on Parkinson’s disease, she explains the fundamentals of the disease in which she highlights that the disease is more than a genetic disease but also influenced by environmental factors. Parkinson’s disease is classified as a neurodegenerative disease that affects motor functions in the body. It is caused from the death of dopamine producing neurons in the substantia nigra or the brain’s control center. The cause of the death of the neurons is still unknown; this makes the treatment and diagnosis of this disease much harder in the early stages. The death of neurons leads to a motor function It is diagnosed in the late stage that is accompanied by trembling, rigidity, slowness

Parkinson disease (PD) is a progressive neurodegenerative disorder characterized mainly by physical and psychological disabilities. This disorder was named after James Parkinson, an English physician who first described it as shaking palsy in 1817 (Goetz, Factr, and Weiner, 2002). Jean- Martin Charcot, who was a French neurologist, then progressed and further refined the description of the disease and identified other clinical features of PD (Goetz, Factr, and Weiner, 2002). PD involves the loss of cells that produce the neurotransmitter dopamine in a part of the brain stem called the substansia nigra, which results in several signs and symptoms (Byrd, Marks, and Starr, 2000). It is manifested clinically by tremor,