Human Blood As A Blood Substitute

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By the end of the 20th century many firms were trying to create a Blood Substitute and had pumped in huge amount of money for its research. Biopure had spent over $200 Million with the primary goal of developing a Human Blood Substitute. It’s entry into the animal market was by chance and their continued efforts in the field was an opportunistic pursuit. However, its animal product called Oxyglobin had received the final FDA approval while Hemopure was about to enter phase III clinical trials. The Oxyglobin and Hemopure substitutes developed by Biopure have an advantage over blood transfusions in many areas including blood type matching, universality in terms of donating, such as O+ blood recipients. The blood substitutes also had a much longer storage life of 2 years as opposed to the 6-week storage life of transfused blood. Furthermore, with the rise of diseases such as AIDS and increasing public concern about the same, blood substitutes also helped mitigate that risk. Baxter International and Northfield Laboratories-products sourced their blood substitutes from human blood whereas, Biopure sourced it from animal blood, cattle in particular. This put them in a better position than their competitors. Also Biopure’s Hemopure and Oxyglobin did not require refrigeration unlike its competitor’s products. As technological improvements and industrialization increased, the use of automobiles increased which also led to auto and industrial accidents. The blood substitutes for

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