Essay on Human Gene Therapy

Human gene therapy is a procedure that is currently being used to help fight diseases with no known cures. Gene testing removes a gene that causes a disease and replaces it with a healthy copy of that gene. By placing a healthy copy of the gene inside the patient’s body, that gene can help fight any diseases, such as different forms of cancer, inherited disorders, immune system discords or viral infections (AIDS). Once inside the cell, the genes produce what the patient lacks, it kills the diseased cells and it activates cells in the immune system.

Genetic diseases are pathological diseases caused by the absence or alteration of one or several genes in the cells of an organism. Most genetic diseases are caused by the inheritance of an altered or missing gene from either one or both of your parents. Because the altered gene is in every cell in your body, including your stem cells, it is practically impossible to physically alter the gene. The only possible effective way that has been found is gene therapy.

Fifty years after the idea of gene therapy was first proposed, gene therapy has become a possible treatment for a couple different diseases. Before this treatment was approved, some serious unfavorable effects were found in clinical trials. However, these effects fueled more basic research in order to improve, in efficiency and safety. Gene therapy has been used for patients with blindness, neuromuscular disease, hemophilia, immunodeficiencies, and cancer.

What is a genetic disorder? A genetic disorder is a disease Inherited medical condition caused by DNA abnormality. The genetic disorder is caused by change or mutation. The name of this disorder is called autism. Developmental Screening and Comprehensive Diagnostic Evaluation is two types of how it gets diagnosed.

Whether gene therapy should be allowed to be used in practice is currently a very controversial topic. In my opinion, I do not think that it should be allowed. Gene therapy is a technique where genetic material is inserted into a patient to replace missing or defective genes. Gene therapy can be further broken down into two categories: somatic and germline. From there, somatic gene therapy can be approached in two ways: in-vivo and ex-vivo. For the process of gene therapy to begin, the proper vector needs to be acquired. Once a vector is chosen, the vector delivers the new gene into the target cell. Then, the target cell becomes infected with the vector. Next, the vector’s genetic material is inserted into the target cell. Then finally, functional

Genetic disorders is an inherited medical condition caused by DNA abnormality. Basically when a mutation happens but this one is worse and the number of chromosomes could be higher or lower. Which may or may not cause a mutation or a genetic disorder. Genetic disorders or related to me because my disorder is with my eyes. I am legally blind and my eyes cross when I don't wear contact lenses or glasses. Because of this disorder I can't drive or work at specific places.

Genetic diseases are conditions caused by abnormalities in the genetic material contained within our cells.

Li, and Huang discuss the controversial topic of gene therapy by first providing a factual summary of gene therapy. Their introduction goes into the specifics of the types of vectors (carriers that deliver a gene to target cells) used to transfer genes in order to aide damaged proteins. Afterwards, they transition into the detailed of process of gene therapy. They start this off with naked DNA and state it is the simplest approach to nonviral transfers and the least toxic method. However, despite being the least toxic and a nonviral transfer it does not have as great of an effect as Cationic lipids. Cationic lipids have been used in various experiments but are known to be safe only when administered in small doses. Furthermore they go into

Gene therapy is an experimental form of treatment, where normal genes are placed into missing or defective ones in order to correct or alter genetic disorders. In other terms, it is the therapeutic delivery of nucleic acid polymers into a patient 's cells as a drug to treat disease (Gennady, 2015). After many attempts at modifying human DNA by nuclear gene transfer as well as insertion of human DNA in the nuclear genome, the first successful gene therapy was in 1990 where it was used to cure four-year-old Ashanti DaSilva who had Severe Combined Immune Deficiency (IDF 2013 National Conference). Since then gene therapy has been used to cure and treat serious diseases such as Chronic Granulomatus Disorder, Hemophilia, and a wide variety of Cancers, and other genetic and acquired diseases (American Society of GENE & CELL THERAPHY, online).

A genetic disorder is an illness that is caused by one or multiple abnormalities in the genome. Genetic disorders are not unusual, however when a genetic disorder occurs it usually happens in one and every thousand or million persons. Sometimes genetic disorders can or cannot be heritable, meaning passed down from the parents to their offspring. Often times the parents are unaware that they can carry over a genetic disorder to their offspring. When genetic disorders that does not occur from the parent, it can mean that the cause for the genetic disorder is caused by a new mutation or changes in the DNA. Most cellular structures consist of proteins that carry out to work and to perform life functions. When a gene is disrupted in a way that the proteins no longer carry out a normal function, a disorder can occur.

What is a genetic disorder? Scientifically speaking it is defined as a permanent alteration in the DNA sequence that makes up a gene. This alteration could be as small as the addition or deletion of a single base pair or large enough to cover multiple genes.

Hereditary diseases are disorders or diseases that are inherited genetically. They are also known as genetic disorders or inherited diseases and may be passed on within the family if there is a mutant gene present. For example, Down syndrome. This disease is also known as Trisomy 21 and it is caused by inheritance of an extra chromosome 21. This condition causes delay in mental and physical development of a child. This genetic disorder is rare and may be detected before a child is born.

Deoxyribonucleic acid (DNA) was discovered in 1944 by Avery and colleagues. Avery identified DNA as the primary genetic material. Watson and Crick later discovered the double helix structure of DNA. Leder and co-workers deciphered the triple nucleotide code that designated the amino acids from which proteins were built. The science of molecular biology was born (Sokol, Gewirtz, 1996). In 1990 a four year old girl who was suffering from severe combined immunodeficiency (SCID) was the first to undergo gene therapy. White blood cells were removed from the girl and the cells were inserted with normal copies of the defective gene and returned into the girls circulation. Her condition improved with four treatments and

Researchers have been trying to find new ways to cure disease for centuries. Gene Therapy

Every living thing is the product of the genes that were passed down from ancestors. Genes make up everything we are. One gets their traits from their parents. Most people live full lives with relatively good health. However, some people inherit mutated genes or faulty genes. This could lead to genetic disorders that could be life threatening. Even today, many genetic disorders still remain incurable, leaving many people without hope. Genetic therapy could be their answer. It is through this research that the cure for genetic disorders can be found. Though some people believe it is unethical or immoral to alter genes, current therapeutics have not been able to save the lives of the patients with these diseases. Genetic therapy