Human Genes Related to Obesity

Is obesity a disease or a human related cause? Researchers have studied this question for years and have come to a variety of different conclusions. Some believe that obesity is a disease and can only be prevented by medications, while others believe that obesity is a human related cause and can be only prevented by a healthy diet and exercise. The American Medical Association (AMA) recently announced that obesity is officially a disease. Dr. Patrice Harris, a member of the American Medical Association

Many studies have been carried out to determine the genetic base of obesity. As result, mono and polygenic obesity have been revealed by scientists with the polygenic form stated as the most common. More than 100 and 200 genes respectively in human and mice have been identified to be related with obesity. As example, a defect in the gene coding for leptin, a hormone involved in regulation of appetite, abnormalities enzyme prohormone convertase that convert the hormone proopiomelanocortin (POMC) into

causes of obesity are deemed to be multifactorial and are the result of genetic, environmental, behavioral, physiological, social, nutritional and cultural factors . Each of these factors related to the cause of obesity lead to an energy imbalance and promotes an increase in fat deposition. Rankenin et al. dected over 300 genes and gene markers that have a central role in the etiology of obesity but , the specifics on which genes promote obesity and which genes are protective against obesity is unknown

The Effects of Genetics and the Environment on Obesity I. Introduction: Many human beings living in the 21st Century are obese or have a problem with obesity. A person is considered obese if they have a BMI of 30 or more. To be obese means you have an excess amount of body fat that can harm your physical and mental health. For most individuals in the population, obesity results from multiple genetic and environmental factors that may interact with, or may be correlated with, each other (Faith

The most rudimentary explanation for what causes obesity is the relationship of energy intake and expenditure and its effect on energy balance. If energy intake is greater than energy expenditure, weight gain will occur. In contrast, energy expenditure in excess of energy intake will result in weight loss ( Dietz & Gortmaker, 2001). However, Obesity is a complex disease that involves interactions between genetics, regulation of energy balance, and strong environmental influences such as increased

Obesity in the United States In today’s world, obesity rate has been increased significantly. Among 196 countries of the world, the Unites States is ranked 19th, and one third of the population in the U.S. have obesity. Reason that people care about how much population is obsessed is that it is “linked to many of the major causes of death in the United States, including heart disease, some types of cancer, strokes, diabetes, and atherosclerosis” (Himes 73). 19th of the world may not seem very high

to a major social issue of childhood obesity. The World Health Organization defines childhood obesity as a ‘serious medical condition consisting in excess body fat that affects children and adolescents.’ To address this problem, assessing the factors that have been suggested as contributing

The recent upsurge in obesity, rates has reached alarming heights with over 30% of Americans now categorized as obese. This has transpired regardless of the fact that our awareness about the importance and effects of maintain a healthy lifestyle and regular exercise are at an all-time high. If one were to impartially examine the statistics on obesity, the only rational assumption is that we are losing the fight on obesity. With countless exercise and diet programs being found to be inadequate to

with obesity, which is usually measured by the body mass index in the experiment. Obesity could lead to type 2 diabetes which is due to the slow metabolic rate and insulin resistance. A scientific research was successfully conducted, which compared Type 2 diabetic-related phenotypes and body mass index between healthy controls and type 2 diabetic patients; They have discovered that type 2 diabetic patients had significant larger body mass index, which was indicating the condition of obesity, the

Candidate genes allow researchers to come up with rational hypothesis of role of these genes and their contribution to different conditions, in this case obesity. Therefore, they are potential predisposition factors. Candidate genes are chosen on a basis of knowledge of their function, biochemistry and their expression pattern (what protein they encode for and where is this protein mainly expressed) in obesity. At present, there are about 300 genes that have been hypothesized to contribute (to some