Human Manipulation Of Genetic Transfer Essay

Genetic manipulation is a powerful tool that allows humans to selectively modify organisms. It provides the ability for humans to deliberately manipulate an organism 's’ genes in order to produce desirable traits. Genetic manipulation provides the ability for humans to decide which phenotypes to express, and which to eliminate. This typically starts with an individual organism, then goes onto eventually effect and entire species or breed.

Humans have been manipulating genetic transfer for over 10,000 years since our hunter- gatherer ancestors began to settle in one place and started farming and planting crops. Those humans observed and chose organisms from natural selection to select and breed organisms that showed characteristics desired by them and this began the process of selective breeding. Selective breeding favours recessive alleles that do not persist in wild populations. Selective breeding is a process of increasing the frequency of rare and recessive alleles so that they appear in homozygous form. This has the effect of eliminating the alleles for wild type from the population and the process of domestication has become irreversible. The domestic species has become dependent on humans for their survival. It is from these domestic species that humans have selected and breed favourable genetic traits for their benefit, be it higher yield in plant crops, sweeter tasting fruit, and more milk from dairy cows or ease of handling stock, selective breeding continues to be used today.

Tay-Sachs disease is a rare genetic disorder that destroys the nerves of the brain and spinal cord (the neurons). Tay-Sachs is usually discovered during infancy, the child appears to be on track and developing normal until the first signs of symptoms become apparent. The children typically do not live past the age of 5 due to many symptoms of the disorder/disease. However there have been individuals with Adult Tay-Sachs Disease (ATSD) and Late Onset Tay-Sachs disease (LOTS) in which they develop mild symptoms later on and worsen throughout the years. The symptoms include: loss of motor skills or muscle movement, vision and hearing loss, intellectual disabilities and dementia, and even can cause paralysis. The most common way to notice a child

In conclusion, Tay Sachs Disease is an auto recessive disorder that can only be inherited by a child if both of their parents are carriers of the trait. The likelihood of a pregnancy resulting in an affected child is one in four. In addition to how the gene is transferred via parents, there has also been research concluding that there is a correlation among those carrying the gene or affected by the gene and their ancestry. TSD is considered to be a Jewish disease due to the high number of incidences of TSD occurring in the Jewish

Tay Sachs Disease is an inherited disease that results in slow destruction of the central nervous system and sensory systems, which is caused by a mutation resulting in a deficiency of a lysosomal enzyme. The missing enzyme, hexosaminidase A, functions in breaking down the fatty material ganglioside GM2, a chemical found in nerve tissue. Without this enzyme, lipids accumulate in the brain cells and destroy them, resulting in damaged nerve cells, neurological problems, and eventually leading to death several years after birth. The disease was first discovered by Waren Tay, a British ophthalmologist in 1881. Tay-Sachs disease is very rare in the general population and is relatively common among certain ethnic groups such as Eastern Europeans

Well what causes Tay Sachs disease is that there’s something wrong with there fifteenth chromosome with this problem your body has trouble making the protein hexosaminidase A, since your body doesn’t make that anymore gangliosides build up and eventually will kill brain cells. In order for your child to get this disease the defective gene has to be passed down from each parent so that would mean that Tay Sachs disease is a heredity disease. If the defective gene just gets passed down from one parent it means that the child is a carrier of Tay sachs disease, in which this means that if this child marries someone who is also a carrier of Tay Sachs disease that means that there child will absolutely have this disease

Tay Sachs is a genetic disorder that occurs when there is a missing enzyme in the body. This causes a buildup of fatty substances in the nervous system (Gale). Beta-Hemosaminidase, or HexA, is the missing enzyme that causes the various nerve disorders that happen within Tay Sachs (NTSAD). This disease is inherited in a few different areas of the world, but it is most commonly

The genetic mutations that cause this disease are more commonly found in the Ashkenazi people with a Jewish heritage than those with other backgrounds. French-Canadian communities of Quebec, the Old Order amish community in Pennsylvania, and the Cajun population of Louisiana, are more responsible for the mutation for this disease. The HEXA has been discovered for the cause of Tay Sachs. The gene provides for making part of an enzyme, which is cause, "beta-hexosaminidase A", which plays an important role in the spinal cord and brain. Disruptions in the HEXA gene messes with the activity of beta-hexosaminidase A, and then prevents the enzyme from breaking down GM2 ganglioside. This results the the substance accumulating to toxic levels in the neurons in the brain and spinal cord. Continuous damage caused by the build up of GM2-ganglioside leads to the destruction of the neurons and thus causes the signs and symptoms of Tay-Sachs

Warren Tay, an English physician who first described the symptomatic cherry-red eye in 1881 (Edelson, 1997). Research later in the 20th century illustrated that Tay-Sachs disease is a genetic disorder caused by a mutation in the HEXA gene on chromosome 15. Many other HEXA mutations have been discovered since then, including different mutations within different populations. Being an autosomal recessive disorder, for an individual to exhibit symptoms it is required to have two Tay-Sachs alleles affected, meaning that when both parents are carriers, the offspring have a 25% of being affected. This disease has shown to be prevalent in certain populations in recent years. Those of Ashkenazi Jewish descent are one of these populations, being more prone to the infantile form of Tay-Sachs disease, caused by a base pair insertion leading to the mutation. More research has led us to believe that compound heterozygosity is ultimately responsible for the disease’s variability among different populations. Those who are heterozygous carriers tend to exhibit abnormal enzyme activity but never show true disease symptoms. This is due to the dominance phenomenon, and with Tay-Sachs being recessive autosomal, it requires

Tay-Sachs disease is also known as: B Variant GM2 gangliosidosis, GM2 gangliosidosis type 1, Hex A deficiency, Hexosaminidase A deficiency, Hexosaminidase alpha – subunit deficiency (Variant B), sphingolipidosis, and TSD. The main cause of Tay-Sachs is a defective Hex-A gene, and an absence of a significant enzyme known as hexosaminidase. A gene on the fifteenth chromosome codes for the generation of Hex-A, and does not function properly in Tay-Sachs patients. Each person has is intended to have two Hex-A genes. Based on inheritance and genetic patterns, even if one gene is defective, the child will still be healthy. Following the inheritance pattern, if two healthy, carrier parents have a child, then that child will inherit a defective gene

Tay-Sachs is a disease caused by a mutation to the gene which codes for Hex A. Without Hex A, a cell cannot degrade GM2 ganglioside into GM3 ganglioside. This results in a build up of ganglioside’s in lysosomes of neurons. The result is varying degrees of mental deterioration. New DNA-based screening is currently being developed to replace the enzyme-based screening techniques that have been used since 1969. This will not only speed up the diagnosis, but also allow for earlier detection of Tay-Sachs by using the parents genotypes.

Tay Sachs Disease is an inherited disorder that kills nerve cells in the brain, and also in the spinal cord. A couple of things that could cause this mutation is a missing enzyme. This is an enzyme called ganglioside, that is a fatty substance. Another reason why tay sachs could appear is a change in chromosomes. This is chromosome number 15. The gene is the HEXA gene, or hexosaminidase A. This is a recessive disorder that you can only inherit if both parents have tay sachs. Some symptoms to know if you have this disease is weakened muscles, startling of loud noises, seizures, hearing loss, blindness, and paralysis. If you’re an infant and you have tay sachs disease, you will start to gain abilities, like crawling, but then start to lose them.

Symptoms of Tay Sachs disease is muscle weakness, lacking of muscle coordination, movement issues, problems with speech, and mental issues. The disease is caused by mutations in the HEXA gene. The HEXA gene is responsible for making a part of an enzyme called beta-hexosaminidase A which is located in lysosomes and plays a key role in the brain and spinal cord. The enzyme helps break down a substance called GM2 ganglioside. The mutation will keep the enzyme from breaking down the GM2 and the substance builds up to toxic levels mostly in neurons in the brain and spinal cord. As the GM2 substance builds up even more, the neurons are destroyed and symptoms began to show.

On the most surface level, human genetic engineering and human genetic modification are a new and rapidly developing field of science that deals with directly altering the DNA (genetic makeup) of a living human cell. From early science fiction to the present day, taking control of humans’ gen es and directing the flow of evolution has been a subject of debate for many people. Human genetic engineering or HGE tends to bring up thoughts of dystopian futures where altering DNA has unexpectedly resulted in horrible mutant humans that can’t survive and thus the human race perishes, but this is not necessarily the outcome. Since genetic engineering is an emerging field of science, there are still many moral and ethical issues that need to be addressed before continuing research. Atheists and theists both have valid reasons to support / resist the continuation of this field of science. For the purpose of this paper, it will be assumed the reader has a reasonable understanding of the terms atheism, theism, DNA, genes, genome, and how a persons DNA (their genotype) essentially dictates the physical appearance and abilities that person portrays (their phenotype).

Author Chuck Klosterman said, “The simple truth is that we’re all already cyborgs more or less. Our mouths are filled with silver. Our nearsighted pupils are repaired with surgical lasers. We jam diabetics full of delicious insulin. Almost 40 percent of Americans now have prosthetic limbs. We see to have no qualms about making post-birth improvements to our feeble selves. Why are we so uncomfortable with pre-birth improvement?” Despite Klosterman’s accurate observation, there are reasons people are wearisome toward pre-birth enhancement. Iniquitous practices such as genetic engineering could lead to a degraded feeling in a child and conceivably end in a dystopian society, almost like the society Adolf Hitler had in mind. In the minds of