Huntington 's Disease : A Progressive Brain Disorder Caused By A Defective Gene

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Huntington 's Disease (HD) is a progressive brain disorder caused by a defective gene. This disease causes changes in the central area of the brain, which affect movement, mood and thinking skills. Nerve cells become impaired, causing several segments of the brain to fail. The disease disturbs movement, behavior and perception the affected people abilities to walk, think, reason and talk are slowly weakened to a point that they eventually become entirely dependent on other people for care. HD is a disease that affects the brain in many different ways. One of the ways the HD affects the brain is that it causes the person who has it to become forgetful and moody. Huntington 's disease also causes a decline in thinking and reasoning skills, including memory, concentration, judgment and ability to plan and organize. HD affects men just as much as it affects women. HD is a genetic disease that affects a gene on the 4th chromosome. The defective gene codes the blueprint for a protein called huntingtin. This protein 's normal function isn 't yet known, but it 's called "huntingting" because scientists identified its defective form as the cause of Huntington 's disease. Everyone has two copies of the HD gene. Part of the gene is a repeated section that is called trincleotide repeat. The code for HD is HTT. A trincleotide repeat is defined ad “a class of clinically heterogeneous disorders defined by the presence of an abnormal and unstable expansion of DNA, triplet repeats in the

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