Huntington's Disease Research Paper

There are many known genetic diseases in the world. There are different types such as chromosomal and monogenic. Chromosomal disorders are when someone has too many or not as many chromosome as they are suppose to have (46 total chromosomes). Chromosomal disorders can also manifest when there are structural abnormalities. Monogenic disorders are an inherited medical condition caused by a DNA abnormalities. These diseases occur all throughout the world today. Depending on what region of the world you are in depends on what the most common ones are. Cystic Fibrosis has become the most common lethal genetic disease in the United States as of 1999. Although there are treatments available, there is not a known cure, and the effects remain burdensome

Developments in medicine have negatively impacted natural selection by causing an increase in genetic disorders. A genetic disorder can occur for many reasons. Sometimes chromosomes are missing or doubled. In other situations, the genetic code on chromosomes can get altered due to an anomaly when the RNA processes the information. Important information can be deleted, swapped, or completely altered. It is because of these changes in chromosomal DNA that changes in species come about. Genetic disorders are the negative effects of mutations in genes. For example, Sickle-cell anemia is a blood disorder which

It is too simplistic to think of a gene mutation as the cause for a genetic disease. Many genetic diseases are polygenic or multifactorial meaning that genes interact with other genes and environmental factors in order to cause the disorder. Some examples of polygenic or multifactorial diseases are diabetes, asthma, manic depressive disorder, and schizophrenia. In such cases

Genetic diseases are pathological diseases caused by the absence or alteration of one or several genes in the cells of an organism. Most genetic diseases are caused by the inheritance of an altered or missing gene from either one or both of your parents. Because the altered gene is in every cell in your body, including your stem cells, it is practically impossible to physically alter the gene. The only possible effective way that has been found is gene therapy.

The genetic disorder I will be discussing is Sickle Cell Disease. Sickle Cell Disease is an inherited blood disorder. Children who have this disease have two defective hemoglobin S genes, which they receive one from each parent. This gene occurs in chromosome 11. The sickle cell gene is passed from generation to generation in a pattern of inheritance called autosomal recessive inheritance. This means that both the mother and the father must pass on the defective form of the gene for a child to be affected. If only one parent passes the sickle cell gene to the child, that child will have the sickle cell trait.

Huntington disease is defined by the autosomal pattern that is in inheritance with high penetrance of high proportion of the population that has the gene that advances the disease. It’s typical that Huntington disease is caused by the loss of neurons nerve cells in the brain (Van Walsem M.R, 2016).

Genetic disorder is a disease that caused by an abnormality in an individual’s DNA. Genetically inherited disorders has only been discovered within the past 150 years. The Incidence of new disorders in our society has led to change into societal attitudes to disease. Some disorders that affect multiple family members are caused by gene mutations (one or more genes) which can be inherited. There also other conditions that appear to run in families that are not caused by mutations. Which instead, environmental factors such as dietary habits or a combination of genetic and environmental factors that are responsible. Passing on mutations are known as monogenic conditions. Monogenic conditions can be inherited in three main ways; autosomal recessive

A genetic disease is any disease or disorder that is caused by mutations in one or more genes. These diseases have the potential to be nonthreatening or extremely lethal. A genetic disease known as Marfan syndrome rests somewhere in between. Marfan syndrome is a disease of connective tissues. This disorder falls under the category of single gene inheritance, meaning that the DNA structure of only one gene is altered. Although only one gene is altered, the results of inheriting Marfan syndrome can display a wide variety of health issues.

Huntington Disease is a progressive brain disorder which causes uncontrolled movements, loss of thinking ability, and emotional problems. There are two types of Huntington Disease, Adult-onset and Juvenile. Adult-onset is the most common form of Huntington Disease and those diagnosed live about fifteen to twenty years after beginning symptoms. The early signs and symptoms include depression, small involuntary movements, irritability, poor coordination, difficulty in making decisions, and difficulty retaining new information. As it progresses, the involuntary movements become more pronounced causing issue with walking, speaking, thinking, reasoning abilities, and personality changes (1).

Gene is the basic unit of heredity in a living organism. It is also composed of the DNA (deoxyribonucleic acid). Huntington's disease is caused by abnormal genes in the nerve cells in the brain. In the global population Huntington's disease evaluates that for every 100,000 people 5-10 people are going to have Huntington's disease. In the United States, 30,000 are affected by Huntington's disease and 150,000 people have 50 percent risk of evolving this disease. Moreover, in middle east countries Huntington's disease is estimated to affect 3-4 people per 100,000. Explaining the history, meaning and how the genes of Huntington's disease inherited helps to realize the disease and its risk.

Huntington’s disease (or Huntington’s chorea) is a hereditary degenerative disease that affects the cerebral cortex and basal ganglia. It is a progressive brain disease that targets the ability to move, loss of the ability to think, and emotional problems. The most common form of Huntington’s is adult onset, appearing in the thirties or forties. As the disease advances,

Genetic disorders or heredity diseases are disorders that are caused by a missing gene, abnormal gene, or chromosomal characteristic (The Free Dictionary, 2007). There are to me found many genetic disorders. Klinefelter syndrome is an example of a genetic disorder. Klinefelter syndrome affects the male rather than female (“47, XXY”, 2016).

Genetic diseases are diseases that are passed on from parents to their offspring. An example of a genetic disease which can be inherited is Huntington Disease. "Huntington Disease is an autosomal dominant neurodegenerative disorder with midlife onset characterised by psychiatric, cognitive and motor symptoms"(G. Vonsattel and DiFiglia, 1998). The statistics for HD blah blah blah Like all genetic diseases, huntington 's disease has a specific inheritance pattern.

Genetic disorders are genetic problems by one/more abnormalities in genomes, a genetic disorder is usually apparent at birth--congenital. Genetic disorders are usually rare and impact one in several thousands, if not millions. Thalassemia (Cooley’s Anemia) is a genetic disorder that is “characterized by absent or decreased production of normal hemoglobin, resulting in a microcytic anemia of varying degree” (childrenscbf.org). Cooley’s Anemia was discovered by two pediatricians back in 1925, and they named the disorder based on what it does to the body and what causes the disorder. Thalassemia symptoms are very specific to the disorder, and it is diagnosed through a series of tests while doctors treat it according

Have you ever wondered the genetic and environmental conditions that many diseases can cause? We will be discussing many diseases such as, sickle cell anemia, cystic fibrosis, and many other diseases that are linked to genetic and environmental conditions. These incredibly sad diseases have horrible effects On the body and that 's what we 'll be covering. We will get to see the ins-and-outs of these genetic diseases and how they affect the body and the environment around them. The components of genetic and environmental conditions will be diseases such as sickle cell anemia, cystic fibrosis, Hemophilia, Down syndrome, Huntington 's disease, cardiovascular disease, diabetes, cancer, asthma, malnutrition, and lead poisoning.