Hypotensive Effect of Aqueous Extract of the Leaves of Phyllanthus Amarus Schum and Thonn (Euphorbiaceae)

The use of natural products as medicine has initiated the isolation of active compounds. The first commercial pure natural product introduced for therapeutic use is generally considered to be

The diuretic activity of Silybum Mariamum L. was higher than that of furosemide or Cistus landaniferus L. In addition, both plants increased urinary excretion of sodium, potassium and creatinine and the effect of Silybum marianum L. was higher than that of furosemide or Cistus landaniferus L.. Interestingly, both plants did not cause changes in the plasma sodium or potassium while furosemide caused hypokalemia. These findings are important since both plants might have a potential to be used as a future diuretics without hypokalemia which is a common finding with use of current diuretics such loop diuretics or hydrochlorothiazide. Because there was no effect of the plants` extract on plasma electrolytes and plasma osmolarity, it might be suggested that the active principle(s) in both plants may has/have a potassium-sparing effect. Furthermore, both plants increased creatinine clearance and studying their effect in kidney failure might explore their potential to help increasing creatinine clearance or ameliorating acute/chronic kidney

Licorice root is used worldwide as a natural sweetener, as well as a flavoring agent. The main composition of plant Flavonoids and Isoflavonoids act as inhibition platelet aggregation, and anticancer, antioxidant (20). Aly et al.,2005(21) indicate that liqurice have potent anti-inflammatory reduction edema about 78.3 while diclofen about 73.9% also have anti-ulcerogenic activity associated with a reduced acid output and an increased mucin secretion, an increase in prostaglandin E2 release and a decrease in leukotrienes (22). Many volatile oil and vitamins such as B1,B2,B3,B6,C,E, Biotin, Foli acid, Pantothenic acid act as expectorant, laxative, liquiritin act as antitussive (23). Also contain Coumarins Herniarin and umbelliferone (24).moreover plant used for treatment of asthma , chronic fatigue, hormonal disturbance , antiviral, antibacterial , hepatoprotective, anti-oxidant , antiulcer, ant mutagenic, Hypothermic antioxidant, anti-inflammatory, relieve pain , expectorant, hypoglycemia,

Although herbs were once the only source of medication available, they may become the future of preventative treatment for Cardiovascular disease. Like everything else in the human body, the Cardiovascular System starts to age, with age comes complications, and sometimes even disease. This journal focuses on the prevention of these diseases by simply using herbs. To elaborate on this, lets first look into what the Cardiovascular System is. The Cardiovascular System is responsible for the moving and removing waste products from the body. Included in this system are blood, blood vessels, and mainly the heart. Some things focused on in this article are the Ethical considerations, the outcome, and the risks of this study.

White W. Utilising ABP recordings to evaluate anti-hypertensive drug therapy. Am J Cardiol 1992; 69: 8E-12E.

Drugs rule the world, or so it appears. Many are approved for specific biological problems, as in the prevention of myocardial infarctions (heart attacks), blood clots due to trauma, surgery, stroke, etc. Conversely, others are recreational, generating instant highs or mellow lows. This essay will discuss one particular drug, chemical structure, cellular mechanism, type of inhibitor, and effects on metabolism.

Numerous number of antianginal drugs have been discovered in the past years, one of particular interest is ranolazine, because unlike calcium channel blockers and beta blockers, ranolazine does not act by effecting blood pressure and heart rate. The FDA approved ranolazine for patients who are still symptomatic despite antianginal therapy in 2006. Exact mechanism of its antianginal effects is not yet fully understood. Ranolazine exhibits a variety of actions, none of which are related to changing the body’s hemodynamic parameters. One of its actions is inhibiting fatty acid oxidation, turning it to glucose oxidation, especially when fatty acid concentrations are elevated during ischemia. However, this effect is not observed until drug reaches high concentrations that are not achieved by usual doses. At higher therapeutic levels, ranolazine exhibits a different mechanism of action.

Administration of poly herbal capsules for 14 days at very high concentrations did not produce any change in haematological parameters in the animals such as total WBC, RBC, Platelet, haemoglobin as well as in the differential count. This again indicates that poly herbal capsules at high concentrations was not toxic to haematological system (Table 5 and Table 6).

Unfortunately very little science has gone behind the modern day claims about medicinal benefits of this herb. It seems like today's opportunistic marketers do not care about thorough research but start drumming up their campaigns at slightest hints of what may be remotely effective.

Echinacea (Echinacea purpurea) is one of the nine species in the Asteraceae/Compositae family, related to the daisy. The North American origin gives insight to its first use in Native American herbal medicine. The plant is commonly used in minor respiratory infection remedies and labeled as a functional food for its properties in increasing antibodies when served in as an herbal drink or pill. Further analysis of this functional food will give light to the common sources, clinical description and side effects drawn from studies to date.

Parsley ( P. crispum ) is a medicinal herb used in folk medicine remedy to decrease the blood glucose level in Turkey (23), and it shows a protective effect against hepatic toxicity caused as a complication of diabetic state (24).The plant therapy can provide blood glucose homeostasis and cannot regenerate the B-cells of the endogenous pancreas.(25) Also parsley has been claimed in folk medicine to possess laxative properties attributed to the presence of some volatile oil that are more concentrated in seeds than in stems or leaves. (25) Parsley have advocated diuretic effect in folk medicine , and it is mediated through an inhibition of sodium potassium pump that would lead to the reduction in sodium and potassium re absorption leading, thus, to an osmotic water flow in to lumen and diuresis. (17)

Phlomis Younghusbandii Mukerjee is a perennial herb (family Labiatae) and grows wildly in Qinghai-Tibet Plateau of China. It has been widely used to treat colds, coughs, sores ulceration, rheumatoid arthritis, pneumonia, bronchitis and other diseases for thousands years. In this paper, 5 iridoid glycosides (sesamoside, shanzhiside methylester, 7, 8-dehydropenstemoside, penstemoside and 8-O-acetylshanzhiside methylester) and 3 phenylethanoid glycosides (acteoside, alyssonoside, and isoacteoside) in the four samples from different places were analyzed by HPLC. The acetic acid-induced writhing test, the hot plate test, the carrageenan-induced paw edema test, the xylene-induced ear swelling test, and the acetic acid-induced Evans blue leakage

pure natural herbal medicines for the treatment and prevention of serious diseases. C1 intends to

Hawthorn is an herbal supplement that has been effectively used to treat various chronic and acute diseases in individuals, but the most commonly used treatment has been for those who suffer from heart conditions. Hawthorn belongs to the rosaceae family and can be found in various regions all over the world, such as Europe, Asia, and North America (Wang, Xiong, & Feng, 2013). In both eastern and western medicine, the berries, leaves, and flowers of Hawthorn have been used in treating diseases that have been associated with the cardiovascular system. Various parts of the plant have been utilized to treat these heart conditions in humans by using the extracts of the plant to make capsules that are ingested or even using the leaves of Hawthorn to make tea. Several in vivo and in vitro studies have been conducted to determine the effectiveness that Hawthorn has in improving cardiovascular function by vasodilating blood vessels, decreasing arterial blood pressure, and lipid lowering effects (Wang, Xiong, & Feng, 2013). Hawthorn is also known to contain chemical constituents that have disease fighting properties that may help in the treatment of heart disease and fight free radical oxidation (Tassell, Kingston, Gilroy, Lehane, & Furey, 2010). The importance of Hawthorn in the treatment of cardiovascular disease, may provide individuals with this condition a safe and natural alternative to the current medications they are taking. The effectiveness of Hawthorn in the treatment of

Herbal medicines are great alternative for commercially manufactured medicines available in the market. The major reason why herbal medicine differ from modern medicine is because they are produced with 100% natural content. Therefore the plant extract has all the medicinal values that are as effective as modern medicine. Commercially prepared drugs show results quickly but have numerous side effects. However herbal medicines don’t show any side