Imagine having a cut on your index finger that starts to bleed. A minor cut, so you think nothing of it. You instinctively put the finger in your mouth, pressing the area with your tongue and teeth in an attempt to stop the bleeding. That fails, so you walk to the bathroom sink, turn the cold-water knob, and place the blood-smeared finger under cool running water. Finally, that does the trick. Slap a Band-Aid on it and you’re good to go, doing whatever you were doing before. This time, imagine the dripping of blood doesn’t stop. That horror is what hemophiliacs have to be cautious of. Hemophilia is a rare blood disease that interferes with the body’s ability to create protein-clotting factors, which is a special protein that is essential …show more content…
Signs and symptoms differ, varying with the kind of severity a patient has. Episodic bleeding is the most prominent symptom. Patients with mild severity usually only experience uncontrollable bleeding after physical trauma or surgery. Individuals with severe hemophilia suffer from frequent and sometimes spontaneous bleeds, ranging from nosebleeds to deep internal bleeding. This must treated immediately due to the possibility of permanent tissue damage or deformity of joints. Other symptoms individuals may experience are extreme fatigue, double vision, low blood pressure, blood in urine and stool, swelling of the joints, along with much more. In the United States, Hemophilia is usually diagnosed in children as early as 36 months post birth for the mild form. It only takes 8 months to diagnose children with moderate hemophilia after birth and 1 month to diagnose severe cases. A simple blood test is the key to a diagnosis of the illness. Prenatal screening can also be used as a method of diagnosis, but comes with risks. As prominent as hemophilia appears to be, it is in fact, a rare disease. Roughly, 400 infants per year are born with the blood illness. Approximately 20,000 individuals in the U.S. have hemophilia and about 400,000 worldwide. That number lacks drastically in comparison to malaria and sickle cell anemia. There is one thing it has in common with sickle cell anemia and that is how it’s acquired.
Hemophilia is a condition where a person's blood is unable to clot properly. This condition can make a simple dental procedure more risky. People who have hemophilia will also have a harder time healing after a dental procedure. You definitely want to let your dentist know if you have hemophilia.
Hemophilia is an X-linked recessive disease in which blood lacks blood-clotting proteins. Females have two X chromosomes, indicating that they are generally carriers and transmit the gene to their sons. People with mild hemophilia bleed after surgery, injury, or trauma. Severe hemophilia produces spontaneous internal bleeding in joints and muscles. Fortunately, medicines and lifestyle changes offers hemophiliacs fairly normal lives. Through learning about hemophilia, I became interested in genetic diseases and finding a cure for those
A parent can pass the abnormal gene for the disease to his or her child. Most circumstances are "autosomal dominant inherited" disorders, which means a person only need an abnormal gene from one parent to be affected. If a person have the genetic factor for von Willebrand disease, an individual have a 50 percent chance of spreading this gene to their children. The harshest form of the ailment (type 3) is "autosomal recessive," which means both parents have to pass an abnormal gene to the young (National Hemophilia Foundation, n.d.).
As the best of my knowledge I believe the two year old child is suffering from an inherited disorder called hemophilia. The Mayo Clinic describes hemophilia as a rare blood disorder that lacks sufficient blood clotting proteins. (Staff, B.M. ((n.d.)). Hemophilia. Retrieved September 27, 2016, from http://www.mayoclinic.org/disease-conditions/hemophilia/basics/treatment/con-20029824
The genetic disorder of Hemophilia is where the clotting factors of the blood are absent or deficient, causing it to be a dangerous disorder to the people who have it. This disorder is where the people who have it will bleed easily and accessibly. Different types of hemophilia are classified by different deficient clotting factors in the blood. Treatments for hemophilia are available, including transfusions of frozen
Theoretically, people afflicted with hemophilia should not survive long enough to reproduce and pass on their mutated genes. However, there are treatments that allow hemophilia patients to live as long as an unafflicted person can. This adjustment to the population has put up a sort of resistance against the allele leaving the population. As far as keeping the allele in the population, the chance of passing it on is always there whether or not the allele already exists in the population. This is because this allele can arise simply from mutations. It does not necessarily need to be an allele that is already being passed around in the family lineage, although it is more likely to inherit the disorder this way. As far as the level of severity goes, the clotting factor level will be about the same from one generation to the next. For example, a son who inherited the recessive allele from his mother will typically have the same severity level as his mother, if she also has the disease or is a carrier of the disease. Another example is that the daughter of a man who is afflicted with a mild recessive allele will typically carry the allele for mild hemophilia as well. This will usually be the case, unless of course another mutation happens upon the existing mutation causing a difference in severity from the parent in comparison to the child. The level of severity is
According to the CDC website, Hemophilia, is a hereditary bleeding disorder which affects mostly males due to X chromosome singularity. Hemophilia is a medical condition in which the blood clotting becomes a challenge for those affected. Symptoms include spontaneous bleeding from injuries or surgery. Blood contains many proteins called clotting factors that assist in blood coagulation, however; those individuals with hemophilia have low levels of either factor VIII or factor IX. The severity of the condition is determined by the amount of factor in the blood thus the lower the amount of the factor, the higher the chances that spontaneous bleeding will occur leading to more severe health complications.
A genetic disorder that affects the blood vessels when injured that results in clotting is Hemophilia. This inherited disorder is not contagious and is found through various lab tests such as a blood clotting test. The way someone can be aware if they could encounter Hemophilia is simply by viewing their medical history,
First described by Babylonian Jews more than 1700 years ago (NCBI, 2011), hemophilia A has been considered a very interesting genetic disease ever since. In addition, hemophilia A gained widespread attention after Queen Victoria transmitted the disease to several royal families in Europe (NCBI, 2011). As scientists gain more knowledge regarding this genetic disease, more effective treatments have emerged as a result.
Acquired hemophilia can be identified by abnormal bleeding into the skin, muscles, or other soft tissues. This usually begins in early adulthood, but it is far more rare than hemophilia A and hemophilia B (Hemophilia, n.d.).
Hemophilia is the oldest know, lifelong bleeding disorder(“Hemophilia”2004). It is named for two inherited diseases in which the blood does not clot normally. Several different plasma proteins must be present for blood to clot property. If one of the plasma proteins is missing, or present at low levels, blood clots very slowly(“Hemophilia” The Marshall Cavendish). The two most common types of hemophilia are: Hemophilia A or FactorVIII(8) deficiency and Hemophilia B of FactorIX(9) deficiency(“Hemophilia” 2002). People with Hemophilia A have low levels of one kind of blood clotting protein and people with Hemophilia B have low levels of another kind(“Hemophilia” The new book).
Hemophilia is the oldest known hereditary bleeding disorder. There are two types of hemophilia, A and B (Christmas Disease). Low levels or complete absence of a blood protein essential for clotting causes both. Patients with hemophilia A lack the blood clotting protein, factor VIII, and those with hemophilia B lack factor IX. A person with severe hemophilia has less than 1% of the normal amount of a clotting factor - either Factor VIII (8) or Factor IX (9). People without hemophilia have between 50-150% of the normal level of factor VIII or IX. There are about 20,000 hemophilia patients in the United States. Each year, about 400 babies are born with this disorder. Approximately 85% have hemophilia A and the remainder has hemophilia B.
A. It 's important to know that hemophilia is not actually a disease or virus. https://my.clevelandclinic.org calls hemophilia "a rare hereditary (inherited) bleeding disorder in which blood cannot clot normally at the site of a wound or injury". This means that it is not contagious, rather it is passed down through genetics. When a hemophiliac gets injured,
When an injury occurs in a patient with Hemophilia, blood pools to the injury site to clot the blood. If the patient has either deficiency factor IX or factor VIII, there is a possibility of activating the factor XI (Stachnik 218). With deficiency factor XI, there may be mild signs and symptoms. Hemophilia can also be caused by inheriting it from family members. Having a family history of Hemophilia can actually help determine if the baby, during pregnancy, has the disease (Mayo Clinic Staff 5). When a female who is a carrier for Hemophilia has symptoms of the disease, it is likely that she could pass her child the affected X chromosome with the gene mutation on the clotting factor (Hemophilia Facts 5). Most Hemophiliacs can tell if they have a family history; however, some families have no prior history. Families with no history would have to contain a carrier female but no affected males (2). In some cases, an affected father and a carrier mother can give the child a combination of chromosomes with a certain deficiency factor, which would result in an affected female child (Blachford 524). Hemophilia can also be caused by acquiring it.
Hemophilia is a problem with the blood in a person that causes them to bleed not any faster than normal, but they often bleed for a longer period. Their blood is missing the clotting factor (a protein in the bloodstream that works to control bleeding). Hemophilia is quite rare; roughly 1 in every 10,000 persons are born with it. Rarely, hemophilia can be an acquired disease which just means a person is not born with it, but will develop it during their lifetime. This rarity occurs when a person's immune system forms antibodies that attack the clotting factor in the blood. The entire antibody population fights against the blood to prevent the clotting factors from working properly.