Immunological Theory of Aging Essay

A recent study was done at McMaster University in Ontario to see whether the signs of ageing were unavoidable. This study involves mice as test subjects that they were designed to age prematurely. The mice was put on a regimen of exercises, where the results have showed that it prevented the signs of ageing and even reverse the early ageing in the mice. The mice that remained inactive have grown with signs of weakened, ill, wizened, and bald. In contrast, mice that were provided with running wheels, they maintained in healthy muscles, brains, hearts, reproductive

Scientist have seen that telomerase expressing clones have no difference in karyotype but have a long lifespan by 20 doublings. With this research, cells have been seen to have a very youthful looking state for much longer. A last area of study is the hypothalamus of the brain. This part of the brain controls reproduction, growth, metabolism, and aging. This is where many of the age related diseases occur. The study of this area can lead to many advancements in age related diseases that can help people live longer. Though this area of study does not have many advancements it holds promising results. Though there have been numerous advancements, many people ask the question whether people need to live longer because of an already over populated Earth.

Humans undergo several stages during their lifetime including growth, development, reproduction and senescence. Senescence is defined as the deteriorative biological changes that organisms experience as they age eventually leading to death. These changes include low metabolism, a weak immune system, memory loss, poor vision and loss of hearing. Senescence begins in humans during their post-reproductive years. However, gerontology research has shown that individuals who reproduce late have longer life spans compared to individuals who reproduce early. Nonetheless, it does not indicate that senescence is inevitable. All organisms experience senescence,

The advancement of medical science impacted greatly on our specie and resulted in improvised life expectancy. Though progression of medical science brings cure for unlimited eternal illnesses it doesn’t however bring any remedy for the havocs caused by aging on our bodies. There

At the National Human Genome Research Institute (NHGRI) they conducted a study on age-related cell damage

It is a known fact that all measures of physiological function decline in human aging. While genetics certainly play a role in the declining of physiological function with age, it can be argued that a fundamental part of aging can be reflected by chemical processes resulting in the appearance of harmful side products of the normal metabolism over time. When enzymes speed up reactions it is harder to slow them down. At the same time side reactions are constantly occurring and more and more unwanted side products are continuously being formed.

Aging is a phenomena we are all familiar with, a trait characteristic of all humankind, in fact, of all living organisms. What are the effects of aging, especially those which go beyond the biological aspects and effect the social aspects of changing roles, seniority, and treatment of the aged? What was the original human condition before high-tech medical interventions redefined death and dying, before the industrial age changed the nature of the nuclear and extended family? Going back still farther, what can the behavior of chimpanzees tell us about the origins of our responses to the aging of those around us?

There are many factors that contribute to the vast differences in physical function in the aging adult. One of these factors is related to immunity. As we age our immunity progressively declines putting us at a high risk for disease and illness. While the decline is gradual it has the snowball effect. The elderly population is much more likely to be affected by these diseases and illnesses (Health, 2011). Disease is believed to accelerate aging biologically speaking (Spirduso, 2004).

(1) The theory that best support my current views on aging is the Wear-and-Tear Theory. The theory is “the idea that changes associated with aging are the result of chance damage to the body that accumulate over time”. (2) As many of us know, the body is constantly renewing itself. The cells in you is constantly creating new ones to replace the old, just like a boat. You are constantly restoring all the parts, where the boat will basically be almost all new parts. I think our body is like a built boat, car, or even a house, you must keep repairing it. Some people would literally get a new body part. A blood transfusion, heart replacement and a leg replacement are some examples of the theory. But just like a used car, boat or house, we stop

procreate”. It’s a known medical fact that as we get older our cells fail to replicate and damage

According to the National Library of Medicine, an individual's immune system slows down with age. Since the purpose of the immune system is to protect the body from harmful substances such as bacteria, viruses, cancer cells, and so forth. When the immune system is compromised, it cannot protect the body the same way it did when it was at full strength.

The main discussion of the article focuses on the topic of whether aging is a

Aging is a part of life not everyone wants to accept. There are many theories on aging and I would like to focus on the Stochastic Theory. The Stochastic Theory is “based on random events that cause cellular damage that accumulates as the organism ages” (Grossman, S. & Lange, J., 2018, p. 55). Within this theory there are four categories but I am only going to focus on two: Wear and tear theory along with Connective tissue/cross-link theory.

The way God created us as humans is a life cycle where eventually late adulthood comes with the biology of aging. Santrock (2013) describes five different theories of why humans age (p. 541). The evolutionary theory explains that aging is more of a natural selection process, and diseases occur in the elderly because they “would have been eliminated” if they were in younger people (Santrock, 2013, p.541). Cellular clock theory describes how cells get tired of dividing after they have been reproducing for so long (Santrock, 2013, p.541). Free-radical theory explains when “cells metabolize energy the by-products include unstable oxygen molecules known as free radicals” (Santrock, 2013, p.541). The unstable oxygen molecules can damage DNA and other structures inside the cell (Santrock, 2013, p.541). Mitochondrial theory describes how aging occurs because of the mitochondria essentially wearing out and becoming less efficient (Santrock, 2013, p.542). Mitochondria are the cell’s “power house,” and they convert energy inside the cell (Bailey, 2008). The last theory, hormonal stress theory, illustrates the effects of stress, especially long term stress, on aging (Santrock, 2013, p.542). Stress released hormones which depress the immune system making people more susceptible to disease (Santrock, 2013, p.542). There are many theories about why human’s age, and all of them may be true, but regardless aging is inevitable and so are its effects.

Aging is the process of becoming older, as we age, multiple mutations occur that concern all the processes of aging well as it compromising a number of different genes. There are many theories of biological aging, such as the Cellular Aging Theory, Immunological Theory, and the Wear and Tear Theory. The Cellular Aging theory describes the process of aging in which cells slow their number of replication, thus giving each species a “biological clock that determines its maximum life span” and how quickly one 's health will deteriorate(Hooyman, 42). After a certain number of years, each cell which follows an apparent biological clock starts to replicate itself less, thus the specific individual or species slowly deteriorates. This theory gives