Impact Of Toxicity Of Commercial Sodium Salt On Kidney And Dna Of Male Mice Part 1

Another way of looking at this is with a simple analogy: consider salt and human health:

Adverse effects can occur if there is too much residual chlorine in water. The use of chlorine can possibly cause carcinogenic compounds such as chloroform. There is still an ongoing debate if chlorine is the best way to disinfect a

Kosher salt is the best option for certain dishes because of its texture, which is coarse and flaky. That coarseness can make the texture of some dishes more interesting. In those dishes, it is usually sprinkled on as a finishing salt.

Many animal studies have shown that lead is capable of causing oxidative stress in many organs (Patra et al., 2001). Toxicity of lead is mainly attributed to the induction of oxidative stress by disruption of the pro-oxidant/anti-oxidant balance, elevation of reactive oxygen and nitrogen species (ROS and RNS, respectively) such as superoxide radicals, hydrogen peroxide, hydroxyl radicals and lipid peroxides, and nitric oxide (Kumar and Reddy, 2012). Currently, N-acetyl-L-cysteine (NAC), derives from L-Cysteine and the precursor of glutathione (GSH), is a well-established cyto-protective drug against drugs induced hepatotoxicity and nephrotoxicity (Whyte et al., 2007; Akbulut et al., 2014), where it exerts antioxidant properties. L-Cysteine was utilized as a chelator of heavy metal to conserve against oxidative stress and inhibit damage to cells and tissues. L-cysteine, a sulfur-containing amino acid, is a nutritionally occurring non-essential amino

The manipulated variable in our project is sodium chloride, commonly known as salt. Sodium chloride is a cube-shaped mineral that is mined all over the world. It is known scientifically as NaCL, and it is made up of 40% sodium and 60% chlorine. Sodium chloride is essential to most living things on Earth. For example, the intake of sodium chloride is essential for the survival of plants. All plants can absorb sodium chloride, but some are more tolerant of sodium chloride than others, allowing them to withstand higher amounts of the chemical. As for all living things, too much sodium chloride can actually be toxic. An accumulation of sodium can drastically alter the chemical composition and nutritional imbalance of the plant, which can lead to changes in growth. Aside from living things, sodium chloride can also affect non living things, such as the freezing process of water. During the process of freezing, the water molecules fuse together to form ice crystals. However, sodium chloride can slow these water molecules down as they are trying to freeze into ice. Adding more salt to a consistent amount of water will prolong the amount of time needed to freeze.

The contamination of water and drinking supplies with high concentrations of nutrients from animal waste has fatal effects on different organisms. “Elevated nitrates in drinking water...hinders the ability of the...blood to carry oxygen” (Hribar 4), which can cause serious health conditions such as birth defects, miscarriages, and can even lead to death in seniors and infants. Although nitrates may have the greatest consequences on younger and older individuals, adults that consume tainted water develop increased risks of “cancer and non-cancer diseases...diabetes...and neurodevelopmental defects” (Halden and Schwab 16). Contaminated drinking water poses a serious threat to human health, and can affect people’s happiness and quality of life.

People claim saltwater is horrible for you; and no matter what can kill you. One problem is that it causes dehydration. A website called Livescience states, “If you took a few gulps of ocean water, for example, your body would have to urinate more water than you drank to get rid of all that extra salt, leaving you thirstier than you were before.” Docastaway states, “A kidney cannot make urine from a concentration of salts of more than 2%.” The saltwater is 3% salt. Therefore, drinking it will leave us thirstier. Drinking salt water for thirst just leaves us more empty in the end. Reasons on why salt water can be good for you is that it can give you a better sleep. Sun Gazing Website states By reducing their levels salt helps to calm and soothe

Cardiac failure in correlation with essential hypertension is the end product of several harmful aftereffects of dietary salt.46 Primarily there is systolic dysfunction due to the salt induced hypertension.47 Some older patients may develop diastolic dysfunction due to impaired ventricular filling, this usually precedes systolic dysfunction and is due to the collagen deposition and fibrosis of the ventricle which are closely linked with salt intake. Also, increase in the size of the muscle mass due to high salt intake, due to the hypertrophy and deposition of collagen and fibrous tissue, thickening of the coronary arteries as a result of high intake of dietary salt, which can be detected as an inappropriate coronary blood flow.48,49

The more salt you eat, so you have to drink more water you have to drink more water. Due to increased stress on the damaged liver. In this way, the viewer will also become inflamed. Your doctor how much salt you consume with your liver safely destroy tells you.

Salty fish dimethyl sulfoxide nitrate produced in the body can be transformed into carcinogens dimethyl ammonium nitrite. Salted egg, pickles also contain carcinogens, eat sparingly.

Chemical-induced organ and tissue toxicity is a worldwide health concern. Liver toxicity, because of the primary role of the liver in the metabolism, detoxification, and elimination of xenobiotics, caused by the exposure to the growing number of chemical toxicants in the form of agricultural, industrial, and pharmaceutical products and food components, additives, and contaminants is the most common organ injury [1-3]. Toxicant-associated liver injury has been associated with a broad spectrum of liver pathologies ranging from acute necrosis to several types of chronic pathological states, including simple hepatic steatosis, nonalcoholic steatohepatitis (NASH), toxic liver fibrosis, and cirrhosis [1,3]. Furthermore, some toxicants may act as carcinogens causing the development of cancer not only in the liver, but in other human organs and tissues as well [4,5]. This indicates that detecting, evaluating, and predicting the potential human risk posed by chemicals continues to remain of great importance.

Cancer is defined as the disease caused by the uncontrolled division of abnormal cells in a part of the body (cancercenter). Different pollutants in water can increase the risk of cancer. These pollutants are caused by oil spills, runoff from agriculture, and urbanization. Although most believe that water pollution is not a factor in the development of the disease, but it has been proven that pollution causes cancer because: Hydraulic fracking releases harmful chemicals that can potentially infect drinking water; Nuclear waste affects local ecosystems and doesn’t decompose within a reasonable amount of time; and preservatives added to water produce a type of water

In various extensive study conducted over time, several effects of sodium on the humans have been described and there is strong evidence that a high salt intake elevates blood pressure and thereby increases the risk of

It may result from excess fluid in the body relative to a normal amount of salt, or it could be a result of loss of sodium and body fluid.

In view of biomarkers of genotoxicity, among the most different literature that are potentially involved in IONs genotoxicity in the mammals (mice and rats) cell lines, it seems that very few in vivo and in vitro studies have investigated DNA damage and clastogenic effect of IONs particularly in aquatic systems (Qualhatoa et al., 2017; Mohmood et al., 2015; Kadar et al., 2011; Wang and Jiao, 2010). For this reason, the genotoxicity and mutagenicity potential of chemical and biosynthesis form of IONPs in different aqua-organisms after acute and chronic exposure remains unclear yet.