Importance Of Hydroxyapatite

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CHAPTER 1 INTRODUCTION 1.1Importance of Hydroxyapatite Hydroxyapatite is one of the calcium phosphatefamily.It containing water with a chemical formula of Ca10(PO4)6(OH)2. (Yasushi Suetsugu) Hydroxyapatite (HA)is one of the essentialbiominerals of interest in the calcium phosphate based bioceramics and the main inorganic composition of teeth and bone.HA is utilized as material fordental and bone substitution.This is because its similarity in chemical to nature bone matrix .Hence,many research had been done to synthetic HA,so that it can use as a replacement to bone ,and as substitution in biomedical applications. In nowadays, HA has various of applications in biomedical. For instance, it used as matrices for drug release control and as materials…show more content…
This means that the solution has to contain more solute entities (molecules or ions) dissolved than it would contain under the equilibrium (saturated solution).Crystallization is also a chemical solid–liquid separation technique, in which mass transfer of a solute from the liquid solution to a pure solid crystalline phase occurs.Usually,the crystalline solid have highly ordered three dimensional arrangement of particles. Crystallization can be divided into two processes, nucleation and crystal growth. Nucleation is the initiation of a phase change in a small region, such as the formation of a solid crystal from a liquid solution.It is a process in which a minimum number of atoms,ions or molecules join together to give a stable nuclei.The rate of nucleation is believed to increase with increasing relative supersaturation. The crystal growth is the subsequent growth of the nuclei that succeed in achieving the critical cluster size.However,rate of the crystalgrowth is only moderate enhanced by high relative supersaturation.Particles with smaller size is produced if crystal growth
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