Inflammatory Bowel Disease: A Case Study

Crohn's Disease Crohn' s disease is a bowel disease characterized by inflammation of the different layers of the gastrointestinal tract. It can be distinguished from ulcerative colitis (a similar disease) in that Crohn' s affects any part of the gut, whereas ulcerative colitis only affects the innermost layer of the colon and rectum. About 15% of Crohn' s patients have severe fistulating disease. In this form, ulcer-like channels develop from the bowel wall and burrow all the way to the skin surface. Eventually, 75% of these patients require surgery. It is estimated that approximately one million Americans suffer from Crohn's and ulcerative colitis. The total cost for Crohn's disease was $43.1 million in 1994. While drug therapy accounted

Crohn 's disease is one of two conditions referred to by the term "Inflammatory Bowel Disease" (IBD). The other condition that is referred to as an IBD is called Ulcerative Colitis. Both Crohn’s and Ulcerative Colitis are conditions that cause recurring or persistent inflammation in one or more sections of the intestine. The literal definition of "inflammation" is "being set on fire". It is a protective reaction that happens when tissue is injured or destroyed. There are two types of inflammations. The first is acute inflammation, which is defined by heat, redness, pain and swelling. The

Crohn’s disease may occur at any age but occurs most often between the ages of 15 and 40 years. Crohn’s disease tends to run in some families. About 20 percent of people with Crohn’s disease have a blood relative with an inflammatory bowel disease. Crohn’s disease rates appear to run higher in those that smoke. This means an individual who may inherit an inflammatory bowel disease, is more likely to develop Crohn’s disease if they smoke (Satsangi, 1996, p.40). Both sexes are affected with the women as a slightly higher chance. Crohn’s disease occurs more often in Jewish and upper-middle class urban populations (Lewis et al, 1996, p.1231).

Clients with ulcerative colitis may experience as many as 10-20 liquid, bloody stools per day.

The development of IBD is very rare in infancy. Inflammatory bowel disease includes, Crohn disease (CD) and ulcerative colitis (UC). IBD manifests during childhood or adolescence in up to 25 percent of patients, however, a small percentage of children may present with IBD in infancy. A published data from epidemiological studies and IBD registries in North America and Europe showed that less than one percent of children with IBD present during the first twelve months of life. Even though the numbers are small, Crohn’s disease is more prevalent than ulcerative colitis in these and other studies. It is also common among infants initially diagnosed as ulcerative colitis or indeterminate colitis to have their diagnosis changed to CD during subsequent follow up. IBD with onset in this age group is likely a heterogeneous group of disorders, and has variability in the clinical presentation and prognosis (Kappelman & Grand,

Crohn’s disease is an inflammation of the gastrointestinal tract that can affect the entire width of wall of any organ or structure pertaining anywhere from the mouth to the anus. The most common site for Crohn’s disease to occur is in the terminal ileum which is the final part of the small intestine or in the ascending colon which is part of the large intestine; both which are located on the right side of the abdominopelvic cavity. Crohn’s disease is one of the two forms of inflammatory bowel disease where the cause of the disease is unknown, the other form being ulcerative colitis (AbbVie Inc,

Ulcerative colitis is an inflammation of the digestive tract. There are four types of ulcerative colitis. Ranging from most severe to least severe Pan-ulcerative colitis, left sided colitis, Proctosigmoiditis, and ulcerative proctitis. Though the causes are unknown there are possibly three factors which may play a part in the disease. The immune system, basically the immune system is fighting itself and inflaming the GI tract, environmental triggers such as certain bacteria’s, viruses, and genetic predisposition. (CrohnsandColitis) Also a lot of theories have been thrown out there, things like salmonella poisoning, and different strands of anti-biotics. (TheMedicalAdvisor)

The most symptoms of ulcerative colitis are abdominal pain and bloody diarrhea mixed with pus, blood and mucus. Individuals may become very sick and weak, they can suffer form anemia, weight loss, loss of appetite, rectal bleeding, loss of body fluids and nutrients, skin lesion, joint pain, and growth failure specially in children according to the extent of the disease. Just how risk factors have a different affects on everyone symptoms are also different. A quarter of the patients only have the disease only have mild symptoms while others suffer from fevers, bloody diarrhea, nausea and severe abdominal cramps. Complications may also occur outside the colon such as arthritis, inflammation of the

Ulcerative colitis, gastroesophageal reflux disease, and Crohn's disease are all inflammatory bowel disease; that is an umbrella term for a group of disorders in which the intestines become inflamed. An ulcerative colitis is when the colon and large intestines are affected. The symptoms come and go, but typically they are severe stomach cramping, diarrhea, and bloody stools. It is hard to decide if it is a serious medical condition because it can go into remission easily. It is treated with decreasing foods that are hard to digest, taking probiotics, steroids, and anti-inflammatory drugs. Crohn's disease is characterized by intense stomach pain, and occurs in the lower right area. It includes diarrhea, bleeding, anemia, and even fatigue. Gastroesophageal

Ulcerative colitis is a chronic inflammatory bowel disease of the large intestine where the inner lining of the colon becomes inflamed and develops tiny open sores, or ulcers, that produces pus or mucous and may cause bleeding. It affects the innermost lining of the large intestine and the rectum. The rectum is always involved in ulcerative colitis. When inflammation only occurs in the rectum, the disease is called ulcerative proctitis. If the inflammation extends into the upper parts of the colon and the whole colon is involved, it is called universal proctitis or pancolitis (Christian Novdqvist). Swelling causes the bowel to move its contents quickly and evacuate frequently. It rarely affects the small intestine.

This issue is of key importance to try and optimize therapy in ulcerative colitis patients undergoing flares of

Patients with active inflammatory bowel disease, who have taken corticosteroids for >3 months either consecutively or periodically, and attend the Gastroenterology Clinic at The Canberra Hospital between September 2017 to September

Inflammatory bowel disease (IBD) can be defined as the chronic condition (it is persistent/ long-standing disease) resulting from inappropriate mucosal immune activation. Inflammatory bowel disease (IBD) can start at any age. However, it is frequently seen among teenagers And also among young adults in their early twenties, both genders can be affected by this disease. There are two conditions that traditionally comprise inflammatory bowel disease (IBD): Ulcerative colitis and crohns disease. Comparison between Ulcerative colitis and crohns disease are clinically useful, because distinguishing between the two conditions allow specialists to choose the right management way. Comparison between Ulcerative colitis and crohns disease are

Colitis was quantified with a clinical score by assessing the weight loos, stool consistency and bleeding of the colon (measured by guaiac reaction, hemoccult) as per cooper 10. If there was no weight loss, then it was assumed and counted as 0 point and weight loss of 1 to 5 % as 1 point, 5 to 10 were given for well-formed pellets, 2 points for pasty and semi formed stools that did not stick to the nus, and nt, 5 to 10 as 2 points, 10 to 20 % as 3 point, and 20% as 4 point. For stool consistency, the stool were collected in a thick paper and observed, 0 point were given for well-formed pellets, 2 points for pasty

Kappelman MD, Rifas-Shiman SL, Kleinman K, et al. The prevalence and geographic distribution of Crohn 's disease and ulcerative colitis in the United States. Clin Gastroenterol Hepatol. 2007; 5(12):1424-1429. PMID: 17904915 doi: 10.1016/j.cgh.2007.07.012