Influenza A H1N1 Virus

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In 1918-19 approximately 50 million deaths were a detriment of the Spanish H1N1 virus pandemic; a respiratory virus. According to the World Health Organization, the second Influenza A H1N1 pandemic in 2009 spread to more than 200 countries causing more than 18 000 deaths. Before the World Health Organization had announced the official end of the pandemic in August 2010, in July 2009 the World Health Organization sent out a phase 6 warning that H1N1 could soon be a global pandemic. It is important to recognize that the 2 different outbreaks had different A/H1N1strains effecting the world population; this suggests A/H1N1has a high ability for mutation, severely complicating the human body’s natural immune mechanism of
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(Cowling, Fang, Riley, Malik Peiris & Leung, 2009) In the investigation conducted by the swine flu investigation team they determined that the transmission in households was completed in less than a week from host to host. (France, Jackson & Schrag, 2010) Still this is significantly less than the school outbreak transmissions (11.3% of household contacts, compared with >30% of school A students) The recommendation to reduce transmission is to encourage domestic discussions about prevention.
PDF Document Attached-Table 2. Symptom Profiles in Groups of Patients with Suspected or Confirmed Pandemic 2009 H1N1 Virus Infection Worldwide. (Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza New England Journal of Medicine 2010; 362:1708-1719May 6, 2010)
An influenza virus possesses 8 genes, 6 derived from the triple North American swine virus lineages and 2 from the Eurasian swine virus lineage. (Cauchemez, Donnelly, & Reed, 2003) Influenza A is a part of the Orthomyxoviridae family of viruses that contains a segmented RNA genome. There are 3 influenza types A, B and C, influenza A and B being responsible for the influenza pandemics. The Influenza A subtype morphology determination is as a result of the antigenic properties of two membrane glycoproteins: hemagglutinin (HA-16 types) and neuraminidase (NA-9 types). In
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