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Influenza Vaccination Characteristics

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Osterholm’s (2011) method observed the following: We searched Medline for randomised controlled trials assessing a relative reduction in influenza risk of all circulating influenza viruses during individual seasons after vaccination (efficacy) and observational studies meeting inclusion criteria (effectiveness). Eligible articles were published between Jan 1, 1967, and Feb 15, 2011, and used RT-PCR or culture for confirmation of influenza. We excluded some studies on the basis of study design and vaccine characteristics. We estimated random-effects pooled efficacy for trivalent inactivated vaccine (TIV) and live attenuated influenza vaccine (LAIV) when data were available for statistical analysis (eg, at least three studies that assessed comparable age groups) (Method, para. 2). His findings revealed that TIV; trivalent inactivated influenza vaccine (dead virus) was effective in eight of the twelve seasons, rendering 67% whereas, the LAIV; live attenuated …show more content…

The assessment reviewed mortality of nine flu seasons from 1996 to 2005 that rendered 115,823 deaths in addition to 20,484 deceased during ‘laboratory-defined flu seasons’ (Fireman, 2009). What exactly does this data present? That the widely accepted belief of the flu vaccination fails to reduce mortality rates the way in which information is portrayed. It is relevant to remain aware that the efficacy of the influenza vaccine is reliant upon a close match of the strain that is in circulation to which, LAIV is recommended for individuals between the ages of two to forty-nine and TIV for that of six months and older. Thus, regardless of what virus is in circulation and if one chooses to receive the vaccination, the recipient’s immune system response, has the final

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