Innate Immune System

What role does the immune system play in keeping the body safe? Please be very specific [9 pts]

The immune system depends on the body’s structures to help it function. For instance, the skin acts as the “body’s first line of defense.” If a pathogen finds a breach in the skin barrier, it is the circulatory system that must now signal the immune system of the invader. Shortly after, white blood cells will be notified of the infection and will target and destroy the pathogen.

Describe how and why both types of adaptive immunity can cause problems with organ transplantation.

Human beings are born with immunity as well as they acquire it from the environment they grow in. Human innate immunity is assigned the task to hinder the harmful substances from entering the body. These immunity barriers develop a defense line. The innate immunity includes cough, tear enzymes, mucus, skin and the stomach acid. Hence, the role of innate immune system is to stop harmful materials from entering our body. In case the innate immunity is insufficient to fight, there is acquired immunity that fights harmful substances by getting exposed to various antigens. The acquired immunity is developed against specific antigen. Its role is to fight

Zinc, number 30 on the periodic table and a bluish-white metallic element, exists naturally in air, water and soil. It is present everywhere in the environment. All life on earth has evolved in the presence of zinc. Natural processes such as erosion, forest fires, aerosol formation above the seas and volcanic eruptions continuously transport Zinc. Zinc melts at about 420° C and boils at about 907° C. Zinc is efficient for plants. Zinc-deficient soils present in many parts of the world are a cause of low crop yields. Not only does it help plants but also the human body. It is responsible for the proper functioning of more than 300 enzymes in the human body, and is vital for the immune system. It will also fight against cold

The immune system contributes to homeostasis as it protects and defends against invaders that pose a threat to the body’s balance. Homeostasis is an internal balance that is maintained by multiple factors within the body. The immune system is responsible for avoiding and limiting infections in the body. It prevents and heals damage that invading pathogens may cause to the body. In this way, it helps maintain homeostasis by eliminating pathogens and the imbalances they cause in the body. A first defense, known as the innate immune response, activates as soon as the body is infected. It is the same regardless of the invader. Examples include skin, chemical secretions, and linings.

Zinc is an essential mineral, it is either added or naturally present in foods. You can find since added in many cold lozenges and a few over the counter cold remedies. There are numerous aspects of cellular activity that zinc is apart of. A few examples would be protein synthesis, wound healing, DNA synthesis, and cell division. While Zinc can also support a normal growth and development for women during pregnancy, as well as a child and adolescence. A daily intake of zinc is needed in order to maintain since the body has no specialized zinc storage system. To determine the proper intake recommendations of Zinc, using the Dietary Reference Intakes can help determine the right amount.

The body of an adult human contains almost 2-3 g of zinc. However, only 0,1% of it is found in the serum. As for other transition metals, circulating zinc is not free, but is complexed to proteins that maintain it in a non-reactive form in order to prevent their toxicity: almost 80% is bound to albumin and the remaining 20% is bound to α2-macroglobulin (Kambe et al., 2015). As zinc is required for many functions in living organisms, its transport across biological membranes is mediated by several proteins that can be classified in two major families of transporters: the SLC39 (Zrt-Irt-related Proteins, ZIPs) family, with 13 members identified, and the SLC30 (Zn-transporters, ZnTs) family, with 10 members (Fukada et al., 2011; Kambe et al.,

Humans such as us alike cannot live in a world without a highly effective defense system that helps us to resist against infections and toxins caused by microorganisms. The immune system is a complex network of consorting cells, tissues and organs that defend the body from pathogens and other harmful substances. This essential complex consists of two subsections : the innate immune system and the adaptive immune system.

Zinc plays important roles in the functioning and homeostasis of the normal prostate, being a major constituent of it and having a concentration three to 10-fold higher than other soft tissues. (2).

The body also needs zinc to make proteins and DNA, the genetic material in all cells

Background: Innate immunity is the first line defense against invading microbes pathogens. Human blood is full of cells that express immune system such as Neutrophils. The most important operation that Neutrophils do in this lab is phagocytosis. Phagocytosis is normal reaction white blood cells doing when human body is under attack from bacterial pathogens.

Fish undergoing internal or external challenges to their state of health mount a vigorous response including activation of both the innate and acquired immune system [1]. The innate immune system which covers those aspects of the host defense mechanisms not dependent on specific response, not only stimulate leukocyte activity but also affects many aspects of the host metabolic processes including immunological response to inflammatory stimuli by activation of phagocytes, and by altered levels of plasma proteins (AAPs). These changes in the plasma proteins have drawn attention to the importance of the innate immune response in fish. Acute phase proteins (APPs) are a large group of biochemically and functionally unrelated proteins whose plasma

The immune response is made up of first, second, and third line defenses. The first two defenses are considered innate responses. These responses are non-specific and typically in place at birth. The first line of defense against pathogens includes the skin and mucous membranes. If a pathogen makes it past these defenses the second and third line of defense step in. The second line of defense includes phagocytes, fever, natural killer cells, inflammation, and antimicrobial proteins. In many cases these first two layers of innate defense are enough to ward off infection.

If a pathogen breaches barriers: innate immune response result into an immediate effect of non- specific response. All Innate immune systems derived from plants and animals, when a pathogen evades the innate response, a third layer of protection is possessed by vertebrates in which activation of adaptive immune system takes place. The immune system response adopts itself within an infection and pathogen recognition is improved. As a result of the improved response, its then retains itself when the pathogen is eliminated in form of an immunological memory and allows the adaptive immune system to mount faster and stronger when pathogen is encountered each time.