Institutional Review Board Summary

This integrative review explores the difference of the onset-to-hospital arrival time between females and males with acute strokes. The results demonstrate that the means and medians of the hospital arrival times among female patients trend toward more delay than male patients, particularly in the Asian-Pacific and Middle Eastern region. However, the various evidences show that gender difference is not statistically significant.

The IRB is a way for participants in research to make sure that their rights as participants are protected and represented fairly in different research projects. The demands of the IRB are simple. The three demands are respect for persons, beneficence and justice. These characteristics are in place to protect the participants in every way possible. The first demand, respect for person, not only means to have respect, but also to be able to provide the utmost protection for the person in a research study depending on the risk factors in the study. Beneficence is the ethics behind the treatment of the participants of the study. This includes the safety and the minimizing any risk factors there may be in the research study. Justice refers to the benefits of the study, meaning the equal treatment of everyone in the study. These are needed as guidelines for researchers to make sure that all researchers are protected in any and every situation they may be put in. As researchers, it is their responsibility to make sure that their participants are protected and the IRB has placed these guidelines so the researchers and the participants know their rights during

IRBs are committees that consist of 5 or more members with varying expertise and diversity that are responsible for reviewing and approving human subjects research activities on behalf of institutions.

URAC stands for Utilization Review Accreditation Commission. It is a process or system by which an independent or self-governing organization utilizes trained assessors to examine an organization’s operations and to guarantee that they are delivering healthcare in the appropriate manner in concordance with the national standards. URAC is known to help promote healthcare quality through the accreditation of organizations that are connected to medical

For conducting a research on the blood, spit or for its further storage, the researcher has to acquire an IRB approval and Informed Consent from the participants. Today, if a researcher fails to determine the participant’s identity, then this leftover tissue can be used for study without the participant’s approval or knowledge.1

An institutional review board is an advisory group that has been formally assigned to endorse, screen, and survey biomedical and behavioral exploration including people. They regularly direct some type of risk advantage study in an attempt to figure out or not which exploration must be completed. The reason for the audit procedure is to guarantee, both ahead of time and by intermittent survey, that proper steps are taken to secure the rights and welfare of people taking an interest as subjects in an exploration study. A key objective of IRBs is to shield human subjects from physical or mental damage, which they endeavor to do by looking into examination conventions and related materials. The convention audit surveys the morals of the examination and its routines, advances completely educated and willful cooperation by planned subjects equipped for settling on such decisions (or, if that is unrealistic, educated consent given by a suitable intermediary), and looks to expand the security of subjects.

In recent years, treatment options for advanced solid tumors have significantly advanced.1,2 Patients now routinely have their tumors genotyped in order to identify genomic markers that can allow their treatment to be personalized with targeted therapies that are less toxic and more effective. Prior studies have found that up to 64% of patients have these oncogenic drivers, and patients with these drivers in their tumors live longer when they are treated with targeted therapy.1 The Profile project was launched at Dana-Farber Cancer Institute and Brigham and Women’s Hospital in 2011 as the platform for Precision Medicine. Profile provides detailed testing on tissue samples obtained during the course of clinical care for a panel of genetic

There was no mention in the article that IRB consent was given. Participants gave implied consent when they agreed to complete the survey. I think that it participants were coerced in completing the survey because they were offered extra credit to complete the survey. I think participants were misled in this survey because I don’t think they knew what was trying to be determined from this survey. I think the Review of Literature was not complete, appropriate to the research question, and unbiased. The references articles used for reference were not current, they were older

The research was conducted under the terms of an application for ethical approval for research

In America today finding a cure for cancer is a huge priority with clinical trails being a big part in these goal there are some newly developed drugs and technology that are making a huge impact in the cancer world.

The 21st century has seen great progress in diagnosing and treating many types of cancers. Advancements in the medical field are helping more people discover their cancer earlier. Doctors are treating more Stage 1 and Stage 2 cancers than ever before. Survival rates are increasing due to early discoveries of tumors. In addition, better medicine and new technology has raised the survival rates of most cancers. More and more people are living beyond treatment and the number of survivors is only expected to increase as time continues.

Figure 3 depicts the different therapeutic pathway being focused on; with 36.5% of trials investigating the development of symptomatic agents and 35.1% focusing on disease-modifying small molecules, with the remaining 23% focusing on immunotherapies, therapeutic devices and stem cell research. Throughout the past decade 244 agents in the United States alone were proposed for marketing, with only one being approved, memantine, indicating a success rate of only 0.4%, the lowest out of any therapeutic industry. The study also identified the fail rate for each stage of clinical trials; was extremely high, decreasing the likelihood of drug progressing to the next stage (Cummings, Morstorf & Zhong

After conducting an extensive, comprehensive review and assessment of the immunization data at the Florida Department of Health Lee County with my preceptors, an evidence-based practice systemic literature search was conducted to contrast and compare the similar practice seen in other Departments of Health around the country. The systemic search process was also done for the evaluation and application of the scientific evidence surrounding practice of the use vaccines and our current immunization process as a whole (Schmidt, Brown, 2015).The idea of adopting and proposing, activities, events and plans, when there is compelling,

Studies for this review were collected using databases such as Google Scholar, Science Direct, and BioMEd Central. Peer Reviewed literature was examined from 2005 to 2015. A total of forty-five studies were examined with ten being used for this review. Cross-Sectional studies and reviews of longitudinal studies were used. Data was collected using primary sources that are first hand observational. Data was collected from questionnaires, interviews, assessment waves, surveys, and focus groups. Most studies were cross-sectional studies (Garcia (2014), Morleo (2013), Lui (2014), Nash (2005), Barnow (2002). Reviews of longitudinal studies were also examined (Jester (2014), Visser (2012), Humskey (2010). A longitudinal study was examined (Degenhardt

The issue that has arisen is that the results in leukemias are especially promising, with up to a 90% response rate. Lymphomas have also responded well, with up to 40% or 50% of patients responding to treatment. This has resulted in high demand, but a limited number of patients that can currently be treated because of the tedious and