Introduction to Crohn's Disaease and Patients Diagnosis

929 Words Feb 16th, 2018 4 Pages
Crohn’s disease is a chronic inflammatory disease of the intestines. Primarily, it causes ulcerations in the small and large intestines but has been seen to affect the digestive system anywhere from the oral cavity to the anus. The disease has no known cure but once the disease begins it proceeds to vary between periods of inactivity (remission) and activity (relapse). The cause of crohn’s disease is unknown but from research it is suspected that infections by certain bacterium could contribute to the disease. The activation of the immune system in the intestines is seen to be of importance to patients with crohn’s. The immune system causes inflammation within the tissues where it occurs. In normal cases the activation occurs when the body is exposed to harmful invaders. With patients with crohn’s disease the immune system is abnormally activated in the absence of any invader, thus resulting in chronic inflammation and ulceration as seen in the figure below. The disease causes abscesses and a cobble stone appearance to the infected area in the body, this infection causes the immune system to activate in an inflammatory response. There are many types of crohn’s disease depending on the severity of inflammation, location and extent. Crohn’s colitis is inflammation strictly confined to the colon. Crohn’s enteritis refers to inflammation…