Introduction to Plasmodium Species

1279 Words Feb 24th, 2018 5 Pages
Transmission of this parasite is due to a bite from a female Anopheles mosquito. Once transmitted, the sporozoite is passed into the circulatory system, which is then advantageous to the parasite as it readily invades hepatocytes. From this point, the life cycle continues and malaria results from infection. A total of five species can infect and are considered transmittable to humans, but for the purpose of this review, Plasmodium falciparum is the most significant.
Deliberated as one of the most dangerous parasites of the Plasmodium species, P. falciparum accounts for at least 75% of all malarial deaths each year (WHO, 2008). According to Hanspal, et al. (2002), P. falciparum has become resistant to antimalarial drugs; therefore the need to develop new approaches has become ubiquitous. Protein affiliations are responsible for not only invasion, but also the creation of a domicile type structure within a host cell which increases the probabilities of infection. By determining these factors, probable correlations to new vaccines or treatments can be drawn.
Consider the life cycle of the parasite, (Figure One) and all of the factors are associated with such, as it plays a role in the involvement of invasion. Once a sporozoite invades a hepatocyte, creates a vesicular body, and undergoes asexual development, the parasite…
Open Document