preview

Introlyte Levels : Case Study

Decent Essays

In the current study, a recorded significant decrease in the electrolyte level ( Na , K, ca and cl) among infected lambs as compared to the non infected ones. In this respect Barkas et al. (2013) attested that the mucosal inflammation of the intestine and the consequential impairment in electrolytes secretion and absorption often lead to acid, base and electrolyte imbalance which may cause diverse complications in body. So, the recorded change in the electrolyte balance could be attributed to the intestinal inflammation produced due to the activity Giardia trophozoites, and this may also interpret the recorded cases of diarrhea which were noticed during the experiment. This aforesaid results came in agreement with other reports …show more content…

In our opinion, this elevation may be created as a result of the increase of nitrogen metabolism in Giardia infection. The high level of MDA among infected lambs is an indication of the oxidative stress produced in the infected tissues (Kılıç 2003) due to Giardia. The decreased activity of the defense mechanism for protecting the tissues from the damage produced by the free radicals might be one of the reasons of elevation the level of MDA among infected lambs (references).
As regard, the significant decrease in the level of serum Nitric Oxide among infected lambs was consistent with other report (Ragbetli.,2014). Nitric oxide formation has been encountered in many parasitic infections including Giardia (Fernandes and Assreuy, 1997; Bayraktar., 2005). It is considered as only part of an immunopathological series against infection (Nahrevanian, 2009). The low NO level may be credited to the release of arginine deiminase by Giardia trophozoites which consumes all the local arginine ( precursor of nitric acid formation). Moreover, flavohemoglobins released by Giardia decrease the levels of NO (Imran 2013).
The malnutrition effect of Gaardia among infected lambs was associated with a low AP level. Since, the hepatobiliary integrity is measured by the serum AP (Brash et al. 2009), so this low level of AP accuses the indirect negative effect of Gaardia on liver tissues and bile duct

Get Access