Kaposi Sarcoma Research Paper

     Distinguishing melanoma may seem hard to do, but is not so once a person is informed on what they should be looking for. They may appear similar to moles, and may be blue or black in color. Though they will usually lack the symmetry and border regularity of a common mole, and may have variance in their coloring. Melanomas can either appear suddenly, or develop slowly near a preexisting mole. In rare cases, melanomas may form on top of previously formed moles or birthmarks, but will also come with the effects of pain, itching, or bleeding. These moles may begin to exhibit new and/or strange characteristics such as

Specific skin cancers including Kaposi's Sarcoma and lymphomas also happen in patients who are HIV positive” (Mayo Clinic, 2013).

I have a few reasons on wanting to examine this topic. I will probably never be able to understand exactly why or how cancer forms or why it affects certain people, I want to try to continue my research over this type of cancer because it is one that has greatly affected my family. The purpose for this paper is to give my audience a better understanding of osteosarcoma and the way it is formed and the symptoms, what metastasized forms of cancer are, and why osteosarcoma mostly happens in children and young

In this video Professor Blossom Damania talked about how KSHV sequence generates primers and how the virus Herpes exist on normal healthy people. I learned that the virus is waiting for something to go wrong so they can harm you. I also learned that KSHV was discovered because of the AIDS epidemic, but I didn't know that Kaposi Sarcoma was around longer than that. I learned that in 1872, Mortiz Kaposi described the cancer in Europe as blotches on the skin, which targeted older men because they are immunosuppressed. I learned that this is because, as you age your immune system goes down. I learned that in the 80’s there was no diagnosis of HIV so if someone show up with Kaposi Sarcoma, the doctors would use this as a sign that they have HIV.

Skin cancer can develop from sun-exposed skin, scalp, face, lips, ears, neck, chest, arms and legs. Virtually anywhere there is skin on your body. It can even form under your fingernails and toenails. Skin cancer affects people with all skin tones. Some of symptoms of skin cancer are a sore that does not heal, large brownish spot with dark speckles. Dark moles that change color, size, feel or that bleed. Dark lesions on your palms, soles or a mucous membrane lining your nose, mouth or anus. A Dermatologist will examine growths, moles and dry patches on your skin to begin the diagnosis. Many Dermatologist use a dermascope to magnify the skin. If they find something they will remove part of it or all of it to do further testing. The doctor or dermatologist will chose one of the many different types of treatment depending on how bad the case may be.

Malignant Melanoma is also called Melanoma or Cutaneous Melanoma. Melanoma is a type of cancer that usually starts with on type of skin cell. The main three skin cells are squamous cells, basal cells and melanocytes. Melanoma starts in the melanocytes. The tumors of melanoma is usually black or brown due to the cells still make melanin. Sometimes it does not make melanin so it will be white, pink, or tan. This cancer can develop on any part of the skin, it is commonly on the chest and back for males and legs for women. The neck and face are other common areas. Having very dark skin can help lessen the risk of getting melanoma in these common areas, but anyone can get it in their nails, bottoms of their feet ,and the palms of their hands. These

There’s different type of cancers that affects the whole body, and in detail there’s different types of cancers on specific parts of the body. Malignant Melanoma is a form of skin cancer, the most aggressive form of skin cancer. Annually, Melanoma kills more than 10,000 people in the United States. More than 76,000 people are diagnosed every year with this disorder. Once Melanoma is spotted, it’s best to seek treatment, the earlier the better. This form of cancer can spread to other parts of the body if it’s not treated early, and it can become fatal. Moles, brown spots, and growth of either of these things is usually where Melanome can be found, for the most part it can be harmless. Although if you see a growth it’s best to contact your physician

April 20th 2011 was the date of the discovery. A cause of SCC is associated with Human papilloma virus, with the oropharynx, lung, fingers, and anogenital region. Exposure to sunlight could also be another cause to SCC, you have to have protection on your skin. With this kind of exposure it is the strongest environmental risk factor. Squamous Cell cancers of the lip and ears are high rates of recurrence and distant metastasis. Individuals on immunotherapy or suffering from lymph proliferative disorders(leukemia) tend to be much more aggressive, regardless of the location. The symptoms might have are highly variable depending on the organ it is on. Lesion caused by SCC is often asymptomatic. Reddish skin blotches that are slowly growing is another sign. If the tumor continuously bleeds especially on the lip, that is another symptom you could look for. Usually the tumor shows as an ulcerated lesion with hard raised edges. Also your tumor grows relatively slowly. A way for SCC to be treated is by surgery. If the doctor diagnoses the cancer they will quickly take you to get it removed. It is almost always curable and it causes minimal damage. But if it

Basal cell carcinoma and squamous cell carcinoma are the most common non- melanoma skin cancers. Other non- melanoma skin cancers are Kaposi's sarcoma and Merkel cell carcinoma. Kaposi's sarcoma is a cancerous tumor of the connective tissue, and it is often associated with AIDS. Merkel cell carcinoma arises from the uncontrolled growth of Merkel cells in the skin. Merkel cells are found in the skin, where their main function is to be touch receptors. It is a rare skin cancer with roughly fifteen hundred cases per year in the United States.

The symptoms range slightly in the different types of skin cancers. Usually a person will not notice symptoms of skin cancer until it becomes rather large. As it gets bigger, it can bleed or even hurt. Consider melanoma. It can occur anywhere on the body. A melanoma may look like a mole, but it is important to know the difference between a mole and skin cancer. The ABCD rule, which stands for asymmetry, border irregularity, color, and diameter provides good guidelines to help differentiate whether a mole is normal or is a melanoma. Some things to look for are a dark spot that is not symmetrical on both sides. Notice if it has an irregular shape with rough or jagged borders, or if the spot is more than one color and not just one solid color. Any of these warning signs should cause alarm and the spot should be examined by a professional for cancer. Basal cell cancer, which is non-melanoma, may be a pink, brown, or black skin growth in the shape of a dome that has blood vessels in it. At first, a basal cell carcinoma can appear as a pearly, natural skin colored bump that looks like a mole or a pimple that won’t go away. These carcinomas are usually delicate or sensitive and can bleed easily. Sometimes these growths can look dark, and may contain waxy, hard skin. Another skin cancer to watch for may appear as slightly scaly patches on skin. This could be squamous cell carcinoma and some symptoms to look for are a bump or lump on the skin that can feel rough and may have a dome-like shape, just like basal cell carcinoma. Also, be suspicious of a bump or lump that feels crusty, one that bleeds as it grows, a sore that doesn’t heal, or one that heals and returns again, or even a flat, reddish, scaly patch that grows slowly. These could indicate Bowen’s Disease, a type of squamous cell

They are initially asymptomatic and slowly progressive but many go on to ulcerate, bleed or become painful. These lesions grow slowly over months to several decades and eventually develop rubbery nodules within plaques. Growth often accelerates once nodules appear [14]. These lesions usually vary in size from 1–5 cm but can reach 20 cm or more in advanced cases. [10,14] DFSP are most commonly located on the trunk (50 to 60%), proximal extremities (20%), and head and neck (10 to 15%). [13] Acral and genital DFSPs are

By definition, a cancer is a disease that is characterized by “controlled growth and spread of abnormal cells,” (Laini, online). According to Laino, cancer forms when there is a growth of abnormal cells. The abnormal cells also known as the cancer cells grow and forms a tumor in which will began to attack nearby body tissues and organs. Depending upon the various types of cancer, the cancer cells attacks different tissues and organs. As the tumor spreads, some

The following five broad categories show the tissue classifications of cancer such as carcinoma, sarcoma, lymphoma, leukemia and Myeloma. Carcinoma is a cancer found in body tissue known as epithelial tissue that covers or lines surfaces of organs, glands, or body structures. Many secretory organs and glands affected by carcinoma cancer such as breast that produce milk. Carcinoma cancers are found to be in 80 - 90 % of patient considering all cancer cases. Sarcoma is another malignant tumor rising from connective tissues, such as cartilage, tendons, muscle, fat and bones. Osteosarcoma (7) (bone) and chondrosarcoma (8) (cartilage) are most important examples of sarcoma, these usually occur in young adults.

A significant number of these tumors are asymptomatic (small lesions usually) and discovered incidentally during a surgery or after routine investigations. When symptoms appear they depends on the size of the tumor and the site of involvement. Most commonly pacients present with GI

General Features of MCC: MCC appears as a nontender red, firm dome shaped nodule that forms in the dermis and immediate subcutis. The tumor consists of densely packed nests or sheets of uniform undifferentiated cells showing the appearance of a so-called small round blue cell tumor. The cells have round to oval nuclei with vesicular to salt-and-pepper chromatin and inconspicuous nucleoli, and the cytoplasm is scant and ill-bordered. Some cases also have relatively irregularly shaped nuclei. The tumor usually has numerous mitotic figures and apoptotic bodies, and