Keratin Disorder: Hereditary Skin Blistering: A Case Study

Dermatofibromas (also known as Fibrous histiocytoma and Fibroma simplex, Nodular subepidermal fibrosis, Sclerosing hemangioma), are common noncancerous (benign) small skin growths. Dermatofibromas are typically detected on the arms and legs. Other common areas are located on breast, face and hands. This growth is usually a benign, single structure that resembles a nipple. Its appearance can be discolored and contains hard, scar-like tissue. A minor injury such as an insect bite, puncture or most recently discovered arsenic, can result in the formation of a dermatofibroma. These growths or nodes only can be found on humans and have not been reported or found other animals. It is estimated that only 1:10 women

Epidermolysis Bullosa is a genetic disorder that causes the skin to blister even with the slightest force. Epidermolysis Bullosa is found in three different types. Each are caused by different genetic mutations. The most common form of Epidermolysis Bullosa (EB) is Epidermolysis Bullosa simplex (EBS). The less common types of EB

Keloid disorder is a genetic condition of the skin. Some individuals are born with the tendency to develop keloids and this does not happen unless there is an injury to the skin. The underlying genetics of Keloids is not well understood. From all we know, and much like most other genetic conditions, there is a wide spectrum to the genetic susceptibility to develop keloids with some individuals suffering from a very mild form of this genetic condition, to those with very

When it comes to treating acne, Asheboro Dermatology & Skin Surgery in West End, NC, has successfully treated patients with Accutane (Isotretinoin), a drug taken orally to help eliminate the redness, scarring and scabbing that’s often associated with the skin condition.

The skin disorders that might results from hereditary, congenital, or acquired pathological processes are ichthyosis, bullous diseases, chronic infections of the skin, dermatitis, hiradenitis suppurativa, genetic photosensitivity disorders, and burns.

The highly regulated process of epidermal keratinization is the result of differential expression of within the epidermis. Basal keratinocytes express intermediate filament keratins 5 and 14. Suprabasal keratinocytes express keratins 1 and 10, which comprises approximately 85% of total proteins found in fully differentiated keratinocytes. Types I & II intermediate filaments (keratins) (Figure 3) are composed of three domains: (1) a central alpha-helical rod domain, (2) an amino-terminal head, and (3) a carboxyl-terminal tail domain both the head and tail globular domains contain end, variable, and homologous subdomains. The central α-helical domain is approximately 330 amino acids long and is divided into four subdomains (1A, 1B, 2A, and

Skin tags are made up of loose collagen fibres and blood vessels surrounded by the skin, collagen is found throughout the body.

One of the most prevalent tumors or skin conditions in recent times is without doubt Seborrheic Keratosis. They may occur at any part of the epidermis and will in most cases exhibit considerable degrees of proliferation. This should quickly dispel other misconceptions that they tend to exist only in areas that are exposed to the ultra violet rays of the sun. Though these are the most common areas, they are not the only places they can be found.

Epidermolysis Bullosa is a group of inherited connective tissue disease that cause blisters that affects layers of the epidermis (outer layer) and the dermis (inner layer) of the skin. Because the skin of the infected person is so thin and fragile they tend to suffer from skin tears exposing areas that can easily become infected. Epidermolysis Bullosa not only affects the skin but has adverse effect to the inner lining of the mouth, throat and gastrointestinal. Also, in severe cases EB affects the musculoskeletal system. Other areas EB may affect are the urinary tract causing painful urination and the airway resulting in breathing problems.

Epidermolysis Bullosa, also referred as “EB” is a very dangerous disease. It can be inherited from parents. It is a common disorder that can affect your skin.

I enjoyed reading your post. Actinic keratosis (AK) is a widespread skin ailment branded by cutaneous lesion of sun-exposed amid fair complex individuals and it augmented the peril of emergent squamous cell carcinoma (SCC) and added skin sarcomas which are a snowballing problem related to the immunosuppressed populace (Dodds, Chia, & Shumack, 2014). According to Cohen (2010), AK predominance in the United States and Australia has overstretched from about 11 percent to 26 percent from research analysis done, and one analysis outcome indicated that about 19 percent of Australians over the age of 40 years with no history of prior AK before the research analysis onset did acquire one or added AK between the

In 2010, Cocciolone et.al. suggested a connection between desmoplastic melanoma and BHD in a 58 year old patient as a result of mTOR up-regulation. There are 6 other cases of melanoma reported in patients with a BHD mutation; although quite possibly the event could be coincidental and a direct link cannot be confirmed (Cocciolone et al. 2010)(Leter et al. 2008).

Knox Dermatology is a dermatology clinic that is located in Dallas, Texas. Knox Dermatology specializes in cosmetic dermatology, medical dermatology, and PRP therapy. Their dermatologist George Wooming, M.D. is skilled in treating acne, cysts, diabetic ulcers, eczema, hair loss, hyperhidrosis, moles, pre-skin cancers, psoriasis, rashes such as poison ivy, and more. Their physician George Wooming, M.D. is a board certified dermatologist.

What impact does Epidermolysis Bullosa have on the lives of the people it affects? It impacts on their lives because of the effect it has on the body’s ability to function properly, mainly because of blisters forming everywhere on the surface of the skin, within the oral cavity and in more severe forms may also involve disfiguring of body parts such as fingers and toes. Many individuals are judged based on their appearance and are severely criticized by use of name calling and such name is referred to as butterfly skin. However, if people are educated about the disease and how it affects individuals it can help bring forth awareness.

Rash is a very general term for nonnative, more or less generalized (not in first place common) defects of the skin which exhibits this redness and / or spots or elevations, usually as a manifestation of an internal disease or disorder. For the description of a skin rash Morphology skin