Kilifi Against Malaria Research Paper

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Strategies used by Kilifi against malaria
During the first decade of the 21st century, malaria-related morbidity and mortality declined dramatically in many Kilifi, but not in all, parts of sub-Saharan Africa. Insecticide-treated bednets (ITNs), rapid economic development of the continent and the introduction of artemisinin-containing combinations as first-line treatment for uncomplicated malaria played important in the controlling malaria.
von Seidlein L et al. discusses the changes in malaria incidence recorded at a single site in Africa over 25 years, along with future implications for disease prevention.
For this trial, author collected a unique dataset d from 69,104 children aged from 3 months to 13 years
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This epidemiological shift is shown by the increase in the mean age of children admitted with P. falciparum infections,
Further, the study reported highest incidence of malaria in kindergarten and school-age children than in infants and very young children.
• The study also focused that malaria control initiatives should target older children and such initiatives like seasonal malaria chemoprevention (SMC) involves a complete treatment course of amodiaquine plus sulfadoxine/pyrimethamine (AQ+SP) for children aged between 3 and 59 months at monthly intervals, beginning at the start of the transmission season, to a maximum of four doses during the malaria transmission season.
• ITNs were highly protective; children who live in communities with high bednet use were less likely to present with P. Falciparum infections than children in communities with low bednet usage.
• The study reported that more effort should be made on community engagement and education to discuss novel architecture houses being built in Africa that improves ventilation while minimising vector entry.
• The study concluded that ITNs and housing improvements will benefit all age groups and provide protection against malaria for adults and
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