Klinefelter Syndrome Research Paper

Klinefelter syndrome (also called XXY syndrome), was found in 1942 by Dr. Harry Klinefelter and is one of the most common chromosomal disorders affecting males. An extra X chromosome is found in the cells of these affected males, meaning they have two X chromosomes instead of just one, the genotype for this disorder is XXY, a normal genotype for a male is just XY. Some affected boys will have more features of the disorder than others, some who have the syndrome could have more symptoms than others who have it. In some cases, Klinefelter syndrome is not found until a boy gets to puberty, and sometimes, men may never be diagnosed with the condition. The most common symptom of this genetic disorder is infertility. Infertility means that you are

This is possible when the XY chromosome combination does not split all the way, creating an XXY combination. This improper division is not restricted only to cats, however it can occur in humans as well, with different outcomes. Although genetically, this creates a unique and rare outcome, it doesn’t do this without any adverse effects. For example, most male calico cats are infertile, so they cannot reproduce and are not of future value to a cat breeder (Moss, 2015). However, they can be valuable on the market due to their

What happens to the body for this to happen? The body has 23 pairs of chromosome in our DNA.With XYY syndrome there is a extra y chromosome due to a split error in the sperm.Normally you have 46 chromosomes in your dna,but if the sperm cell has a error when it splits that can result with there being an extra y or x chromosome,the y chromosome either moves to a cell or leaves a cell before the cell splits in half and can cause there to be just a x chromosome or y chromosome which leads to a cell having to y chromosomes in one cell.That happens due to a cell spilt error.

What klinefelter syndrome? Klinefelter syndrome is a random mutation that happens during the sex cells reproduction. It's caused one extra copy of the X chromosome in each cell (xxy), the most common cause. An extra x chromosome in some of the cells (mosaic klinefelter syndrome), with fewer symptoms. More than one extra copy of the chromosome, which is rare and results in a severe form. Error in cell division, called nondisjunction, results in a egg or sperm cell with extra x chromosome mosaic klinefelter syndrome is caused by random mutation during fetal development.

My brother Jett Balanay was diagnosed with Klinefelter Syndrome. Klinefelter Syndrome is a genetic condition in which a male is born with an extra X chromosome. Instead of the normal forty-six X,Y chromosome of a male, Jett has forty-seven chromosomes which are X,X and Y. In my previous research I provided information about Klinefelter Syndrome, the signs and symptoms, the history of Klinefelter Syndrome, and a list of health care providers that are available to help treat males with Klinefelter Syndrome. This paper will provide detailed information about the three major facets when addressing treatment for males with Klinefelter Syndrome. The three major facets are hypogonadism “diminished hormonal or reproductive functioning in the testes or the ovaries,” gynecomastia “abnormal enlargement of the breast in a male,” and psychosocial problems “of or relating to the interaction between social and psychological factors” (Dictionary, 2015)

These treatments should be started as early as possible. The seizures are often easy to control and treat. At the initial time, antiepileptic drugs will be used to prevent seizures, but this therapy cannot be used to treat behavior or language problems. If there is no effect, doctors will take the therapy of ketogenic diet or treatment with intravenous immunoglobulin. Multiple subpar transections (MST) is a controversial treatment, which is applied for children who are unable to speak a language fluently and

Klinefelter syndrome is a genetic disorder caused by an extra X chromosome that leads to disabilities in men and has a complex cause. This syndrome is caused when a male has an additional X chromosome with the regular X and Y chromosomes. Klinefelter syndrome occurs by a process called nondisjunction. This condition occurs by a process called nondisjunction. When chromosomes are wrongly allocated into the sperm of egg, it is known as nondisjunction. Nondisjunction is when, during egg or sperm formation(meiosis), a pair of sex chromosomes does not separate. When that sperm or egg with the extra X chromosome is joined with a normal egg or sperm, the zygote made by the two will have 3 sex chromosomes instead of the usual two. This zygote is then said to have a trisomy, which is simply a zygote with 3 copies of a chromosome, as such in Klinefelter's syndrome. On the other hand, a monosomy is a zygote which is missing a chromosome. Usually, when trisomy and monosomy happens in a non-sex chromosome, (autosomal), it is lethal,

Kartagener’s syndrome is a rare hereditary genetic disorder. This disorder affects the respiratory tract, middle ear, fallopian tube, and the flagella of sperm cells. This disorder starts in the embryologic phase of development. The diagram shows you the main internal structure and anything missing or deformed in the central microtubules to the dynein arms causes the protein to not properly link together.

After karyotyping through amniocentesis, our team of obstetricians and cytogeneticists have identified a non-disjunction. This was done through taking a sample of amniotic fluid containing fetal skin cells and placing it in a laboratory dish with chemicals and hormones to allow the cells to divide rapidly. After a week, we applied colcemid, a drug that stops mitosis at the metaphase stage. Various other chemicals were then applied to swell the cells at the metaphase stage of mitosis and the cell was placed in a microscope slide to dry. Gimesya dye was then applied to identify the different chromosomes in the cell and a picture of the stained chromosomes was taken. The chromosomes were arranged by size, which were then analyzed.

Klinefelter syndrome is a chromosomal condition that affects male's physical and cognitive development. Males with Klinefelter syndrome don’t know they have it, so they lead normal lives. Klinefelter syndrome occurs in about 1 to 1000 males. The cause of Klinefelter syndrome is the presence of an extra X chromosome in males often occurs when the genetic material in the egg splits unevenly, but it also can happen when the genetic material in the sperm splits unevenly. Men with Klinefelter syndrome don’t have obvious symptoms. Others may have sparse body hair, enlarged breast, and wide hips. Almost all men their testicles remain small. Their voices may not be as deep and they cannot father children.

The most common karyotype is the paternal 47,XXY which account for over three fourths of those with Klinefelter’s syndrome, but there are a small number of cases (10-20%) that have a “mosaic karyotype, 46,XY, 48,XXY or 48,XXYY.” (Maiburg, 2012). It is believed that Klinefelter’s syndrome develops after sister chromatids fail to separate correctly or separate early during meiosis I, and this is thought to be the main cause of infertility (Maiburg, 2012, pg 254). Males can inherit this from either their mother or their father, although the nondisjunction happens at different stages of meiosis, if inherited from the mother it could have happened during meiosis I or II, whereas in the father it has to happen during meiosis I (Maiburg, 2012, p 254). Just like with other genetic disorder’s age of the parents, particularly the mother, also play a sizeable role, in the development of Klinefelter’s

Klinefelter syndrome is a genetic condition when a male has an extra sex chromosome, XXY instead of XY. Males usually grow without knowing that they are diagnosed with the Klinefelter’s syndrome. However, doctors can tell a male that is diagnosed with Klinefelter syndrome by testing the chromosomes of the person through blood samples. Another way, doctors can tell a male with Klinefelter syndrome by taking

Kennedy's Disease goes by many names that are given following (many are same and just arranged or spelled by differently):

The non-disjunction is the failure of one of the pairs of homologus chromosomes to separate during meiosis I or II. The consequences of non-disjunction in meiosis I results to a gamete containing both homologues of one chromosome pair (Disomy), and non-disjunction in meiosis II leads to a gamete with two copies of one of homologues of the chromosome pair. In both situation the other gamete will have a missing chromosome. If the two chromosome gamete will be fertilized the future zygote will be trisomic, if the fertilized gamete is the one with a lack chromosome the future zygote will be monosomic.

Klinefelter syndrome, also known as “47, XXY”, is a chromosomal disorder caused by nondisjunction. Nondisjunction occurs when chromosomes do not separate fully during meiosis. This results in sex cells with the wrong number of chromosomes. A zygote with two X chromosomes and one Y chromosome forms when a normal sex cell, which is a sperm or egg cell, combines with a sex cell which has an extra X chromosome. The extra X chromosome will show up in the karyotype of an infected individual. Individuals with Klinefelter syndrome have two X chromosomes and one Y chromosome, giving them a total of 47 chromosomes, as opposed to the normal 46. Unaffected males have one X and one Y chromosome, and females have two X chromosomes. Even though individuals