Lab Report: Titration Of An Antacid

An acid is a compound that donates hydrogen ions when dissolved in water. A base is a compound that releases hydrogen ions when dissolved in water. When an acid and base are mixed together, they neutralize each other, forming a salt and water.

The purpose of experiment three was to identify the unknown component in the drug Panacetin. The use of physical properties can help identify unknown compounds and estimate the degree of their purities. In this experiment, solubility in boiling water and melting point were used to determine if the unknown was acetanilide or phenacetin. Since both compounds are soluble in boiling water and insoluble in cold water, recrystallization was used to remove any impurities from the solid.

Ever wonder about the chemical makeup of tablets that people take for pain relief? Before a tablet can be successfully made, the limiting and excess reactants must be considered. The limiting reactant will affect the amount of the product that can be made. Another reason why the starting reactants must be determined carefully is to make reduce the amount of the reactant in excess so that reactants are not wasted. This experiment uses an Alka-Seltzer tablet. Alka-Seltzer dissolves in water and is an antacid and a pain reliever1. The Alka-Seltzer tablet has many uses such as relief of headaches, ingestion, heart burns, or even upset stomachs2. The active ingredients in an Alka-Seltzer tablet is aspirin, also known as acetyl-salicylic acid (C8H12O4), citric acid (C6H8O7), and sodium bicarbonate (NaHCO3)2. The aspirin in the Alka-Seltzer tablet helps with pain relief. Because of the acid-base chemistry (Brønsted-Lowry), citric acid and sodium bicarbonate produce O2, which makes the tablet fizz when it is dropped in liquid. The Brønsted-Lowry theory shows how the Brønsted-Lowry acid donates a hydrogen ion while the Brønsted-Lowry base accepts the hydrogen ions3. The remaining NaHCO3 that is in excess post reaction with the citric acid is what is used to neutralize stomach acid which helps relief heart burn2. The problem in

The purpose of this lab is to investigate the composition of a compound suspected to be Panacetin, a type of pain-killer. Panacetin is typically made up of sucrose, aspirin, and acetaminophen, but the third component in this experiment is unknown. The unknown component is suspected to be a chemical relative of acetaminophen, either acetanilide or phenacetin. Using techniques such as extraction, evaporation, and filtration, the three components will be isolated based on their solubilities and acid-base properties. Then, the percent composition of Panacetin can be deduced based on the masses of the three dried components. The

Neutralization reactions are those that involve the reaction of an acid and a base to form water and salt. A solution with a high hydrogen ion concentration is acidic, and a solution with a high concentration of hydroxide ions is

Pre-Lab: Analgesic drugs are known for reducing pain, while antiseptic drugs reduce symptoms such as fevers and swelling. However, some of these drugs can reduce both illnesses. To obtain a pure compound in these drugs, the scientist needs to separate the desired compound by taking advantage of the different physical and chemical properties. Such as; different boiling points, melting points and their solubility properties. To do this a chemist can also asses the differences between acidic and basic substances when they are added to water soluble mixtures. Within this current experiment I will asses the

weak bases). After ranking the pH of these solutions, you will then test your predictions in the laboratory.

To start out this study the difference between acids and bases has to be identified. Acids have very low pHs and have a high concentration of hydronium ions, while bases have a high pH and have a high concentration of hydroxide ions. The difference between strong bases and acids, and weak bases and acids is the amount of dissociation. Strong bases and acids dissociate a large amount and let go of their ions in solution, while weak bases and acids may only let go of some of their ions. This is important because if the unknown solutions aren’t strong acids or bases then using their ions to calculate the pH of the solutions will give false results (Diffen 2012).

Bases are a substance with a pH higher than 7, and have a high concentration of hydroxyl ions. Bases can react with acids in order to neutralise them in order to form salt and water. Bases are normally metal oxides or metal hydroxides. Sodium hydroxide for example is a base.

a. Aqueous Sodium Hydroxide—NaOH (aq) is a very strong base, which will completely disassociate into Na+ and OH- ions, which would make it a very strong electrolyte. Chemical reaction of the disassociation of Sodium Hydroxide: NaOH (aq)Na+ (aq)+ OH-(aq)

Sodium metal is extremely reactive in comparison to hydrogen due to its ranking in the activity series, and when combined with water, it would displace one of the hydrogens in a water molecule, forming NaOH, also known as sodium hydroxide (Beran, 2014). This compound is known to be basic because it can donate a hydroxide ion, and all basic substances turn litmus paper blue (Beran, 2014).

The build up of stomach acid may cause irritation and excess pain to individuals. Luckily, antacids being a weak base can help relieve the symptoms and pain. Antacids, such as Gelusil, Medi-Firs, Alka Seltzer, and Alcalak are neutralizing agents of acids that become helpful to the human body when heartburn occurs. Heartburn, also known as acid reflux is a common medical issue that occurs when hydrochloric acid (HCl) from the stomach moves backward along the digestive track to the esophagus (located within the throat). This reverse flow of fluids causes a burning sensation due to and possible sour taste that is characteristic of acids [1].

The stomach is an expandable muscular sac that is capable of holding 2-4 liters of food and liquids and breaks them down with the use of pepsinogen, an inactive form pepsin, a protein-digesting enzyme. If the stomach was damaged or dysfunctional, then it would be harder to gradually release food into the small intestine at a rate suitable for proper digestion and absorption and to digest the food because it is not as small or digested because the stomach also assists in the mechanical and chemical breakdown of the food as well as the killing of harmful bacteria due to the high acidic environment due to the hydrochloric acid. (Audesirk, T., & Audesirk, G. (1999). Retrieved November 21, 2015 from Chapter 29: Nutrition and Digestion. In Biology:

generally act as a catalase that initially bring about a chemical reaction.” Enzymes play an

is the phosphate group, and at the other end is one of several nitrogenous bases.