Leukemi The Bone Marrow

Leukemia is a cancer of blood cells, specifically white blood cells that are responsible for fighting infection. However, the abnormal cells in leukemia do not function in the same way as normal white blood cells. Leukemia cells continue to grow and divide, eventually crowding out normal blood cells. The end result is that it becomes difficult for the body to fight infections, control bleeding and transport oxygen (Medicine Net, 2015). It is estimated that each year, approximately 30,800 individuals will be diagnosed with leukemia in the United

Types of leukemia- acute or chronic: Acute leukemia gets worse very fast and may make you feel sick right away. Chronic leukemia gets worse slowly and may not cause symptoms for years. And Lymphocytic or myelogenous: lymphocytic affects the white blood cells called lymphocytes and myelogenous affects the white blood cells called myelocytes.

According to the American Cancer Society (2013) stated, “Leukemia is a cancer that starts in early blood-forming cells” (American Cancer Society, 2013). “Most often, leukemia is a cancer of the white blood cells, but some leukemias start in other blood cell types” (American Cancer Society, 2013). “Any of the cells from the bone marrow can turn into a leukemia cell” (American Cancer Society, 2013). According to the American Cancer Society (2013) stated, “Once this change takes place, the leukemia cells don’t go through the normal process of maturing” (American Cancer Society, 2013). There are changes that leukemia cells can quickly reproduce themselves and not die when they are suppose too (American Cancer Society, 2013). “They survive and build up in the bone marrow, crowding out normal cells” (American Cancer Society, 2013). “In most cases, the leukemia cells spill into the bloodstream fairly quickly” (American Cancer Society, 2013). “Almost all childhood leukemia is acute leukemias” (American Cancer Society, 2013).

Leukemia is cancerous disease that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the blood-stream (National Cancer Institute, 2008, para. 1). It is one of many complicated cancer diseases that affect all ages and have very negative outcomes if not treated properly, and on time. Within the disease are several different types that affect according to how quickly the disease develops and attacks the body. It could be classified as chronic leukemia, which has a slow progress of getting worse or acute leukemia which usually gets worse quickly. The types of leukemia also can be grouped based on the white blood cell that is affected (National Cancer Institute , 2008, p. 1).

Leukemia broadly describes conditions that affect erythropoiesis in the bone marrow, lymphatic system, and spleen. As with all other cancers, leukemia begins from the mutation of DNA in certain cells. Classifications of leukemias are based on the age of onset and the leukocyte involved (Lewis et al. 2014, 665). The most common leukemia is chronic lymphocytic leukemia (CLL), accounting for approximately 30% of cases in the United States (Copstead and Banasik 2013, 222). The normal function of the bone marrow, spleen, and liver becomes interrupted by the invasion of malignant lymphocytes (B cells); since the B cells are functionally inactive, a patient becomes more susceptible to infections. The sluggish progression of CLL unfortunately leads to late diagnoses and poor prognosis (Lewis et al. 2014, 665). Patients that become symptomatic in later stages will experience fatigue, weight loss, anorexia, and an increased susceptibility to infection, due to abnormal antibody production. Patient specific factors such as age, disease progression, and medication side effects will determine the course of treatment (Copstead and Banasik 2013, 223). The fragile state of patients with CLL requires continuous examination of drug therapy and interventions to prevent further complications.

Leukemia is a type of cancer that sadly causes around 25,000 deaths in the U.S. each year. The area that it affects is the blood and the bone marrow and like most or all of the types of cancer in the world if not taken control of early it will most likely kill you.

Cancer is a very general term that can refer to many different diseases. The different major classifications of cancer are Carcinoma, Leukemia, Myeloma, Lymphoma, and Sarcoma. Carcinoma is a cancer of the external or internal linings of the body such as epithelial tissue. Leukemia is a cancer of the bone marrow. This is also known as blood cancer, because bone marrow is the site where blood cells are produced. Myeloma is a cancer found specifically in the plasma cells of bone marrow. Lymphoma is a cancer that develops in the lymphatic system. The cancer appears in the nodes, glands,

Multiple myeloma, also known as myeloma, hematologic cancer, or cancer of the blood is a plasma cell cancer, a type of white blood cell made in the bone marrow that is responsible for creating antibodies. A Multiple myeloma diagnosis means a group of these plasma cells has become cancerous and is multiplying. This cancerous multiplication of plasma cells raises the the level of abnormal proteins in circulating blood, and reduces the space available in the bone marrow for making healthy plasma cells . Health problems caused by multiple myeloma can affect your bones, immune system, kidneys and red blood cell count. The lifetime risk of getting multiple myeloma is 1 in 149 (0.67%).

Multiple myeloma is a form of cancer that results from the uncontrolled growth of abnormal plasma cells. Plasma cells are a type of white blood cell produced in the soft tissue inside bones (bone marrow). These are cells in your blood that normally help you fight infection. They are part of your body’s defense system (immune system). Plasma cells that become cancerous will grow out of control. As a result, they interfere with normal blood cells and many important functions that normal cells perform in the body. With multiple myeloma, the abnormal plasma cells cause multiple tumors to form.

The type of cancer I chose to write about is called acute lymphoblastic leukemia. Acute lymphoblastic leukemia is developed through damaged bone marrow and blood cells. Stem cells form blood cells, these stem cells that form white cells start out as cells then generate into blast cells, or also known as lymphoblast. Lymphoblast then produce a cell a type of white blood cell known as lymphocytes. This damaged cell then becomes a leukemic cell and multiples into billions of cells leukemic lymphoblast cells. This then causes the number of healthy blood cells to drastically lower. The origin of the word "acute" comes from the fact that the disease progresses rapidly and creates immature blood cells, rather than mature ones. It also can be called acute lymphocytic leukemia. Acute lymphoblastic leukemia is a

Myelodysplastic Syndromes, also known as MDS are a family of rare blood disorders in which the bone marrow fails to make enough healthy red blood cells, white blood cells and platelets. Instead it produces undeveloped or immature cells that die in the bone marrow or die just after entering the blood stream; they also have an abnormal shape, size and or look. Some types have no known cause. Others occur in response to cancer treatments or chemical exposure. Symptoms may include shortness of breath, fatigue, easy bruising, and paleness. Myelodysplastic syndrome may lead to leukemia; transfusions and medications help manage symptoms. Medications or bone marrow transplants may lessen transfusion needs and slow or prevent progression to leukemia; As a result, blood counts are usually low in people with MDS. As the number of healthy cells declines in a

Leukemia is a cancer that affects the bone marrow. The bon marrow is the soft spongy center of the bone that produces blood cells. Leukemia is found in white blood cells or leukocytes. The white blood cells help to fight ff infections and other diseases. Normally, cells produce in an orderly way, but people that have leukemia the cell production gets out of control. The marrow produces too many immature white blood cells called blasts. They are differently shaped and can’t carry out their usual duties.

Acute Lymphocytic Leukemia is a scary disease. The term “acute” means the disease can quickly spread and progress quickly and can prove fatal in months if left untreated. “Lymphocytic” simply means that it develops from immature forms of lymphocytes. Also known as Acute Lymphoblastic Leukemia, or ALL for short, it is a type of cancer that starts from the early form of white blood cells called lymphocytes in the bone marrow. ALL is the most common form of cancer in children, though adults can get it as well. For children, treatment results in a good chance of a cure. Adults have a significantly smaller chance of a cure with ALL. ALL generally invades the blood very quickly and has the potential to spread to other body parts such as the spleen,

Leukemia is a type of cancer. Cancer is a group of more than 100 diseases that have two or more important things in common. One is that certain cells in the body become abnormal. Another is that the body keeps producing large numbers of these abnormal cells. Leukemia is cancer of the blood ce3lls. When leukemia develops the body produces large numbers of abnormal blood cells. In most types of leukemia, the abnormal blood cells and they do not

There are two types of leukemia in children; acute and chronic. Acute is fast growing leukemia. Within acute leukemia are three categories: acute lymphocytic (lymphoblastic) leukemia (ALL), acute myelogenous leukemia (AML), and hybrid or mixed lineage leukemia. Acute lymphocytic (lymphoblastic) leukemia (ALL) is the most common type of childhood leukemia and develop from early forms of lymphocytes, also known as white blood cells. Specifically, three out of four childhood leukemias are ALL (About Childhood Leukemia). Acute myelogenous leukemia (AML) starts from the myeloid cells that create blood forming cells such as white blood cells (except for lymphocytes), red blood cells, and platelets (About Childhood Leukemia). Hybrid or mixed lineage leukemia are rare forms of childhood leukemia, but can be treated like ALL and AML. On the other end of the spectrum is chronic, or slow growing, leukemia. Chronic leukemia is difficult to treat and are more commonly found in adults than children. There are two types of chronic leukemia: chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL). Chronic myelogenous leukemia (CML) is not commonly