1. As shown in this case study, the patient was hospitalized very often due to severe acute pain caused due to microvascular occlusion. There can be two possibilities for the symptoms of pain- increase in intra-medullary pressure or periosteum of the soft tissue of her bones. Her report shows a very high serum ferritin level which is due to mutation in hemochromatosis gene (HFE). This increased the level of iron in her body. Due to abnormal liver enzymes, the liver eventually stopped carrying out its normal function causing Alanine Aminotransferase(ALT) to increase. Her ALT level was persistently increasing which means she can be suffering from acute viral hepatitis. She is suffering from diabetes due to the formation of glycated protein. She didn’t get her periods on time because of the lack oxygen being transported throughout the body. Hypogonadotropic hypogonadism can be observed in her body due to some problem in the hypothalamus or pituitary gland. The reason behind abnormal FSH, LH and Oestradiol in her body is because of iron deposition in the endocrine gland. One more reason for the increase in iron level can be due to multiple blood transfusion in her past. It is appropriate to undergo chelation therapy since her liver iron …show more content…
This approach can be advantageous to beta-thalassemia. This approach will increase the ration of sickling haemoglobin vs non-sickling haemoglobin. When BCL11A is silenced in the mice, the stem cells cannot engraft in the bone marrow. This could deliver ineffective gene therapy, causing difficulty in blood formation. Knocking down of BCL11A provided many layers of engineering. The researchers used short hairpin RNA (shRNA) that inactivates BCL11A gene. ShRNA was inserted in microRNA where it was joined to the promoter of beta haemoglobin expression. This is how this whole bundle was inserted in
Gina is a 21-year old nursing student who saw her primary health care provider after experiencing episodic blurred vision, fatigue, poor motor coordination and urinary incontinence. Her neurological exam revealed mild ataxia and mild weakness in her left leg without severe spasticity. MRI scan of the brain reveals multiple plagues indicative of multiple sclerosis.
A review of the records reveals the member to be an adult female with a birth date of 08/15/1953. The member has a diagnosis of Multiple Sclerosis. The member’s treating provider, Juan Barrera, MD recommended the member treatment using the prescription medication H.P. Acthar Gel 80 units/ml vial for an acute exacerbation of her multiple sclerosis.
Case Study: A thirty six year old male has developed severe muscle weakness throughout the body. The condition began fifteen months ago with a left foot drop and within a year, he described difficulty with speech and swallowing, muscle twitching and cramping, and muscular atrophy throughout the upper and lower limbs. Within the last two months, his breathing has become more difficult, and there has been a noticeable difference in his voice. Prior to the fifteen months, he presented little to no symptoms. The patient, a medical doctor, has a wife and two young children.
Incurable disease? No not me. At the young age of only fourteen I had been diagnosed with an incurable disease that would change my life FOREVER. This disease called, Multiple Sclerosis, is a non-curable neurological disease that impacts the nerves in your brain and spinal cord. It can be hereditary in some ways, but doctors have yet to find a direct cause of the disease itself. Symptoms can range from tingling or pinprick feelings, to blurred vision, and even the loss of mobility in your limbs and in other areas of your body. This disease has impacted me more than physically, it has impacted me emotionally and spiritually as well. Although, this is a serious medical condition, I have overcome and learned to accept the fact that I am a little different than everyone else.
When considering this information, keep in mind that while you may not have MS, a lot of people do, and are diagnosed with it every day. Raising awareness about MS and getting more people involved is one of the best things you can do to helps others suffering with this
Multiples sclerosis, also known as MS, is a disease in which a patient’s immune system attacks his or her central nervous system. Within the central nervous system, the myelin sheaths of individual nerves are attacked and damaged causing a break in communication between the patient’s brain and his and her body. The location of this disease is within the myelin sheaths on the nerves located in the central nervous system.
The physical medical condition, Multiple Sclerosis is a disease that can develop at any time. It consists of several severe symptoms that affect the mental, physical, emotional well being, and motor functions of an individual with MS. When diagnosed with MS, there are four different typed of MS: Clinically Isolated Syndrome (CIS), Relapsing-Remitting MS (RRMS), Primary-Progressive MS (PPMS), and Secondary-Progressive MS (SPMS). These types of MS with the help of a Magnetic Resonance Imaging (MRI) can determine the status of the prognosis of an individual with MS. Even though there is no cure to MS. The information provided about MS is detrimental for any individual to experience. The onset and process of MS can take so much out of an individual.
Multiple Sclerosis is a disease that can impact many different parts of the body. It starts out by the immune system attacking the myelin that surrounds the nerve fibers in the Central Nervous System. Once the myelin tissue is damaged, it forms a type of scar tissue that essentially causes the sclerosis. It then sends nerve impulses back and forth between the brain and spinal cord that can cause many different ranges of symptoms. Scientists are still researching the cause for this disease; however, there have been great advancements since it was first discovered back in the eighteen-hundreds. From conducting research over the years, scientists have been able to collect data that gives a further insight into how MS works. There is no cure
Imagine waking up with a steady tremor of your hands, an unpredictable pain in the head and
Hemochromatosis is a genetic disease in which there is too much iron that builds up in your body, this is referred to as an iron overload. Iron is an essential nutrient found in many foods but can be toxic to our bodies if we have to much. “Normally, humans absorb about 8-10% of the iron found in foods that they eat.” People with Hemochromatosis can absorb up to four times more iron than a normal human being. Since our bodies have no natural way to get rid of the extra iron, it gets stored in your body tissue including the liver, heart, pancreas and many other areas of our body can also be infected by this iron overload.
Multiple sclerosis, also known as MS, is one of humankind’s most mysterious diseases. No one knows the exact cause and there is no exact treatment. Still multiple sclerosis has the ability to affect nearly 3 million people worldwide and at least 500,000 people in the United States (Boroch). This disease tends to be more common in individuals of northern European descent and women are more than twice as likely to develop multiple sclerosis as men. Of those 3 million people, most of them are between the ages of 20 and 50 years old (Dangond). Even though multiple sclerosis is a mystery disease, scientists are working to determine the exact cause and treatment.
Multiple Sclerosis is an autoimmune disorder where the myelin sheath within the Central Nervous System is attacked (National Multiple Sclerosis Society, 2017). The myelin sheath protects the axon of the nerve cell. When the myelin sheath is intact, the axon is able to carry impulses away from the neuron’s cell body, and the message carried is clear. With Multiple Sclerosis, the myelin sheath becomes scarred, hence the word “sclerosis”, and distorts the nerve impulses traveling over the CNS (National Multiple Sclerosis Society, 2017). This may cause the message to be changed or stopped altogether.
Multiple sclerosis, or MS, is a disease of the central nervous system. The central nervous system is made up of the brain and spinal cord. Both have nerve fibers that are wrapped in a myelin sheath. In MS, the myelin sheath becomes inflamed and gradually is destroyed. With the destruction of the myelin sheath comes an array of symptoms that may include numbness or tingling, balance problems, weakness, muscle spasms, and blurred vision.
a). Based in my family history, one of my grandfather died at age of 65 of multiple sclerosis (my mother’s dad). My other grandfather died at 101 years old (my dad’s dad), and my two grandmothers are still alive, one has almost 100 years old (my dad’s mother), the other has 89 and she is very active and she still does not need glasses to read (my mom’s mother). My mom (62 years old) has diabetes and high blood pressure and my dad (68 years old) he has no issues at all with his health. I ’am 31 years old, my only issues are migraine and scoliosis. I try to do exercise, eat clean and take care of myself. Considering my dad’s side of the family and my grandmother’s genes and if I keep a good routine of healthy habits, I’ll say that I’ll have
People from all around the world may think they are different compared to others in other countries. If they believe so, they are wrong. Countries like India, Japan, and the United States are homes to millions of people. With the large amount of people living in these countries. There must be problems within the country as well.