Lisinopril And Levofloxacin: A Case Study

The role of diuretics in heart failure is to reduce the fluid retention by diuresis (1). Patient should be monitored closely to prevent over diuresis that will subsequently lead to hypotension and renal impairment. Diuretic used is commonly associated with hypokalemia (1). Thus, additional potassium needs to be given concurrent to diuretic treatment (1). Patient’s daily weight must be recorded and aimed for reduction of body weight >4.5 kg in 5 days after treatment (7). Angiotensin converting enzyme inhibitor (ACE-I) is a first line agent in treating heart failure, especially when there is evidence of reduced in ejection fraction <40% as it improve survival rate of patient (1). Patient needs to be advised regarding side effects of the drug which are, dry cough, hypotension, renal insufficiency, hyperkalemia and angioedema. Antihypertensive agents that can be given in patient with heart failure are beta blocker, ACE-I and aldosterone antagonist. If the blood pressure is persistently high despite treatment with beta blocker, ACE-I and ARB, calcium channel blocker such as amlodipine can be added as this drugs has negative inotropic effect

Metoprolol is a common drug utilized to treat a range of cardiovascular problems including hypertension, heart failure, acute myocardial infarction, arrhythmia and tachycardia among others (Sagent, 2016). It acts as a beta blocker that specifically targets beta-1 adrenergic receptors found in the heart. Stimulation of beta-1 adrenergic receptors causes an increase in cardiac output by increasing heart rate (through action on receptors in the SA node) and contractility (by acting on the receptors in the myocardium). As a result, blocking these receptors with metoprolol would cause a decrease in heart rate, contractility, and blood pressure, ultimately alleviating some of the problems mentioned above (Brodde, 2008).

ACE inhibitors are important and useful in the medication and treatment for KH due to their effectiveness in treating hypertension. ACE inhibitors will help treat KH by slowing the angiotensin converting enzyme (ACE). Angiotensin II is produced by the body that can cause vasoconstriction of the blood vessels. Angiotensin II is made from Angiotensin I by the ACE. If the production of Angiotensin II is slowed by the ACE inhibitor, the blood vessels will be able to dilate, and blood pressure is able to be lowered (Copstead and Banasik). Thus, it is important for KH to stay on the ACE inhibitors due to his blood pressure readings. KH’s blood pressure is 135/96. His systolic blood pressure is in the pre-hypertensive range, however, his diastolic blood pressure is in the hypertensive range and therefore, his blood pressure is hypertensive. Since his blood pressure is high, it is important for KH to remain taking the

I am concerned with the drug to drug interaction with Mrs. Cynthia. She has hypertension, type II diabetes, and she is old. Her body mechanism metabolism the medication at a slower rate or it may metabolism too quickly. Cynthia labs result closely because she is also diabetic and is taking Lisinopril. I am concerned with her taking a potassium-sparing diuretic, potassium supplement, and aspirin. Patients who are taking potassium-sparing diuretics, potassium supplements, potassium-containing salt substitutes should not be placed on Lisinopril (mmm ) Lisinopril is

Mr. S is a 29-year-old male with past medical history of (PMH) hypertension (HTN) and obesity who presented to local emergency room (ER) with headache and chest and back pain. Mr. s had been seen at urgent care three days prior for a headache and near syncope and was told to hold his metoprolol due to bradycardia. Due to health insurance related problem, he has been off amlodipine and lisinopril for a month.

When being prescribed with controlled release nifedipine, Mrs Luv would be advised to take great caution because she may be more sensitive to the effects of the drug because of her age. She would be instructed to swallow the medication whole (no chewing, breaking or crushing the tablet) with a glass of water and not to abruptly stop taking the medication without consultation with her physician. She would be informed that controlled release nifedipine may

Usually angiotensin has an effect on the body to increase blood pressure, increase blood volume and increase pressure in the kidney. As the ACE inhibitor lowers the amount of angiotensin, this causes the blood vessels to become wider and there is an increase in the amount of urine produced by the kidneys. The result of this is the blood pressure goes down, blood volume decreases and decreases pressure in the kidneys. The decrease of angiotensin levels by ACE inhibitors also causes a drop in noradrenalin and aldosterone levels, which helps to reduce blood pressure. Another effect ACE inhibitors have is to increase bradykinin which also causes the blood vessels to widen with a further decrease in blood pressure. Examples of ACE inhibitors include; Lisinopril (Prinivil), Captopril (Capoten) and Enalapril

ACE inhibitors such as Captopril block activity of the enzyme ACE and therefore the conversion of angiotensin I to angiotensin II (the most bio active product of the RAAS), thus inhibiting the actions of angiotensin II and leading to decreased aldosterone production, decrease blood volume and reduced hypertension. ACE inhibitors also work to decrease fibroblast activity as a protective measure against remodelling of the left ventricle (19). Side effects of ACE inhibitors include a dry cough due to the inhibition of bradykinin break down, hypotension and hyperkalemia (due to higher levels of potassium reuptake). ACE inhibitors are currently one of the drugs of choice to treat patients with HF.

How would you help Mr. Anderson understand why it is important for him to take the aspirin and the Lisinopril?

One of the most common treatments for heart failure is ACE inhibitors. ACE inhibitors have shown to slow down the course of heart failure and decrease cardiovascular mortality (1). Overall, they work by suppressing the activity of angiotensin II. ACE inhibitors prevent the conversion of angiotensin I to angiotensin II by competitively inhibiting the activity of the angiotensin converting enzyme. Since angiotensin II is a vasoconstrictor, the lack of the protein allows blood vessels to remain dilated which decreases blood pressure. In addition, the lack of angiotensin II decreases aldosterone release which further lowers the blood pressure and puts less strain on the heart. Angiotensin II has been shown to be involved in the myocardial

In the modern medical society, scientists/doctors have adopted the use of medicines known as Angiotensin-converting enzymes or ACE inhibitors which are ideal for treating kidney, blood vessel and heart problems (Updated by: Michael A. Chen, 2015).This particular medicine works by lowering blood pressure and ultimately manages any disease to prevent it from getting any worse. Often patients with heart failures will be prescribed with this medicine. This essay will give a detailed explanation and description of the benefits, side effects as well as the physiological mechanism of ACE inhibitors.

A 66-year-old man presented to the emergency room complaining of increased swelling of the back of his throat and difficulty breathing. Despite treatment with epinephrine, antihistamines, and corticosteroids, the patient's condition progressed from that of severe laryngeal edema to total laryngospasm and complete airway obstruction. Emergency measures to intubate the patient were complicated by severe swelling of his neck and oropharynx, forcing the physician to perform a grossly traumatic tracheotomy. The difficulty encountered during intubation deprived the patient of oxygen for a significant amount of time, precipitating cardiopulmonary arrest. The anoxic episode resulted in hypoxic, ischemic

You should know that Levofloxacin like all the antibiotics could have some side effects but this not means that we cannot use it at all. You cannot use levofloxacin if you have irregular heartbeat and taking some antiarrhythmics, has history for myasthenia gravis and if you are allergic from quinolones. Anyhow you can use levofloxacin to treat your bacterial infection( if you don't have above mentioned problems) associated with a lot of fluids for the full course of treatment , and during this period of treatment should be aware for any symptoms and to talk with your doctor before you stop

Atacand HCT (Candesartan celexetil-hydrochlorothiazide) was developed for patients who were unsuccessfully treated with single antihypertensive agents. The proposed benefit is elicited by the drugs action on angiotensin II receptor antagonists, the agent that causes vasoconstriction. Additionally the second ingredient hydrochlorothiazide a diuretic reduces blood pressure by improving the kidneys ability to eliminate salt and fluid from the body (www.centerwatch.com).

Captopril treats HBP and congestive heart failure “Captopril is an oral drug and a member of a class of drugs called angiotensin converting enzyme (ACE) inhibitors” (Ogbru, 2014 ). “Administration of captopril results in a reduction of peripheral arterial resistance in hypertensive patients with either no change, or an increase, in cardiac output”