Literature Research and Essay: Sleep Deprivation and Cardiovascular Disease

4518 WordsJan 31, 201818 Pages
What is the recent evidence that links sleep deprivation with an increased risk of cardiovascular disease? Introduction Recently, many epidemiology studies were conducted to find out the effect of sleep deprivation on the risk of cardiovascular diseases. Sleep deprivation is a concern for the working population especially the shift-workers. If sleep deprivation leads to cardiovascular diseases, they are at higher risk of suffering cardiovascular diseases such as hypertension, myocardial infarction and stroke. I chose five recent studies that provide an insight of the relationship between sleep deprivation and cardiovascular diseases. Sleep restriction increases the risk of developing cardiovascular disease by augmenting proinflammatory responses through IL-17 and CRP A cohort study was conducted by van Leeuwen et al to investigate the effect of sleep deprivation on the cardiovascular system through immunological response (van Leeuwen et al., 2009). Nineteen healthy young men with regular sleeping behaviour had physical screening. The experimental group (n=13) had sleep duration of 4 hours for 5 nights, followed by recovery sleep (8 hours) for 2 nights. Proliferation of IL-17, a proinflammatory cytokine increased significantly after sleep restriction and its concentration was not reduced to baseline level after 2 nights of recovery sleep. In addition, significant increase of C-reactive protein (CRP), an inflammation marker was also measured and its concentration

More about Literature Research and Essay: Sleep Deprivation and Cardiovascular Disease

Open Document