Literature Review: The Hormone Theory Of Ageing

This assignment will explain what changes in the body happen visually and physically when we naturally age, the identification of the chronic condition Diabetes and how it’s related to the natural ageing progress with suggestions of treating the client with this chronic condition that is receiving medical treatment and the result for doing this outside the area of expertise. Also the differences, intrinsic and extrinsic factors between natural ageing and premature ageing.

Scientist have seen that telomerase expressing clones have no difference in karyotype but have a long lifespan by 20 doublings. With this research, cells have been seen to have a very youthful looking state for much longer. A last area of study is the hypothalamus of the brain. This part of the brain controls reproduction, growth, metabolism, and aging. This is where many of the age related diseases occur. The study of this area can lead to many advancements in age related diseases that can help people live longer. Though this area of study does not have many advancements it holds promising results. Though there have been numerous advancements, many people ask the question whether people need to live longer because of an already over populated Earth.

The elderly population is growing rapidly and now makes up greater than thirteen percent of the United States population. (APA, 1994). With such a record growth, there are different aspects to aging that are still being analyzed. Many may think of reaching late life as a rite of passage, but many face this time with a different view. Through the movie "UP', we are granted an opportunity into view the struggles of an elderly widowed man by the name of Mr. Fredrickson and the challenges in which he faces in his later life. The movie, takes one on a journey through his sorrows and his triumphs until he realizes what the true meaning of happiness is.

Humans undergo several stages during their lifetime including growth, development, reproduction and senescence. Senescence is defined as the deteriorative biological changes that organisms experience as they age eventually leading to death. These changes include low metabolism, a weak immune system, memory loss, poor vision and loss of hearing. Senescence begins in humans during their post-reproductive years. However, gerontology research has shown that individuals who reproduce late have longer life spans compared to individuals who reproduce early. Nonetheless, it does not indicate that senescence is inevitable. All organisms experience senescence,

It is a known fact that all measures of physiological function decline in human aging. While genetics certainly play a role in the declining of physiological function with age, it can be argued that a fundamental part of aging can be reflected by chemical processes resulting in the appearance of harmful side products of the normal metabolism over time. When enzymes speed up reactions it is harder to slow them down. At the same time side reactions are constantly occurring and more and more unwanted side products are continuously being formed.

In order to better understand aging-associated diseases, it is first necessary to define what aging is. Aging is a complex, multifactorial process of harmful mutations in cells and tissues that are accumulated over time and result in an increased risk of disease and, eventually, death (Tosato, Zamboni, Ferrini, & Cesari, 2007, p. 401). Contrary to the belief that aging can be cured through medical advances, it is scientifically accepted that, while human life expectancy has increased, the human life span has remained largely unchanged for the past 100,000 years (Tosato et al., p. 401). Therefore, future developments in aging research ought to focus on addressing treatment and prevention of major aging-associated diseases that will

There are thousands of genes which relevance for the pathobiology of aging, but there are few genes may control the rate of aging. Other than that, some theories of aging point to the influence of genetics redundancy in the aging process and others are concerned with insufficiency of repair system, which aging result from the accumulation of somatic damage or unrepaired DNA lesion. It is not clear whether age related based in repair mechanism which may be intrinsic to the aging process, reflect information encoded in the DNA, environmental effects or the interaction of genetic and environmental effects. This show both genetic and environmental mechanism are probably important to intrinsic aging

The purpose of this news is to notify us that scientists now understand better why aging occurs, researchers from the Institute of Molecular Biology (IMB) in Mainz, Germany found out that the genes which cause aging belong to a process called autophagy which boosts health and fitness in youth but drive the process of ageing later in life. It also demonstrates that ageing is something humans can not avoid. To do this research the researchers shut down autophagy in old worms and they saw there was a strong improvement in neuronal and subsequent whole body health. In the article of The tech museum of architecture they state that there are two theories of why we age, one is that our genes decide how long we live, and the other one says that as we live our DNA gets damaged until we can no longer function as we are supposed to do. They also talk about the experiment with the worms and how by mutating certain genes they can expand their lifespan up to 4-fold, which for humans would be the same as 300 years. There is another article were their research is about trying to prove that ageing is universal and is the same for all living things, however they found that is has many variables depending on the animal.

Telomeres shorten after each cell division, until senescence marks the point, where they cease to divide. Once cells divide at a reduced rate and then no longer divide at all, the effects of ageing become visible. It should be noted that this is not the inevitable fate of every biological organism. As we reach the heights of sentience, our evolution would be reflected in our extended lifespan. From a scientific viewpoint, the human race has the capacity to expand their lifespan from 150 to 300 years in less than a century. Therefore, we have far from lived up to our full biological

Research has also shown that accelerated AGE formation and accumulation is characteristic of chronic conditions such as diabetes and heart disease, as well as ageing, renal disease and neurologic degeneration.

this theory is an important theory that talks about the biology of humans. However, this theory also talk about how ageing is planned or programmed into our body systems. Based on this theory, there are three key systems that associated with the ageing process. These three systems are: endocrine (hormonal) system, the immune system and the genes. All, these three systems make some changes as time goes on and these changes causes the symptoms and signs of ageing.

The way God created us as humans is a life cycle where eventually late adulthood comes with the biology of aging. Santrock (2013) describes five different theories of why humans age (p. 541). The evolutionary theory explains that aging is more of a natural selection process, and diseases occur in the elderly because they “would have been eliminated” if they were in younger people (Santrock, 2013, p.541). Cellular clock theory describes how cells get tired of dividing after they have been reproducing for so long (Santrock, 2013, p.541). Free-radical theory explains when “cells metabolize energy the by-products include unstable oxygen molecules known as free radicals” (Santrock, 2013, p.541). The unstable oxygen molecules can damage DNA and other structures inside the cell (Santrock, 2013, p.541). Mitochondrial theory describes how aging occurs because of the mitochondria essentially wearing out and becoming less efficient (Santrock, 2013, p.542). Mitochondria are the cell’s “power house,” and they convert energy inside the cell (Bailey, 2008). The last theory, hormonal stress theory, illustrates the effects of stress, especially long term stress, on aging (Santrock, 2013, p.542). Stress released hormones which depress the immune system making people more susceptible to disease (Santrock, 2013, p.542). There are many theories about why human’s age, and all of them may be true, but regardless aging is inevitable and so are its effects.

Telomeres are directly correlated to the aging of a human body. Although some people might think that shorter telomere lengths are detrimental, the natural shortening of these telomeres are essential to healthy and normal aging. It is natural for cells to divide through mitosis, but each time cells are split telomeres are lost through the process. This is why the telomere maintenance system was evolved to protect the ends of chromosomes (Prescott, Kraft, & Chasman, 2011). Every time a cell is divided, its telomeres are weakened, and stress can accelerate this weakening, and biologically age the person. As a

Aging is the process of becoming older, as we age, multiple mutations occur that concern all the processes of aging well as it compromising a number of different genes. There are many theories of biological aging, such as the Cellular Aging Theory, Immunological Theory, and the Wear and Tear Theory. The Cellular Aging theory describes the process of aging in which cells slow their number of replication, thus giving each species a “biological clock that determines its maximum life span” and how quickly one 's health will deteriorate(Hooyman, 42). After a certain number of years, each cell which follows an apparent biological clock starts to replicate itself less, thus the specific individual or species slowly deteriorates. This theory gives

Causes of aging are very uncertain. Besides, there are several factors which predispose an individual to premature aging. Current theories suggest that this process occurs to due to cellular damage such as DNA oxidation by free radicals causing